[논문]Glucosylation of the flavonoid, astragalin by Leuconostoc mesenteroides B-512FMCM dextransucrase acceptor reactions and characterization of the products

Kim, Go-Eun; Kang, Hee-Kyoung; Seo, Eun-Seong; Jung, Sun-Hwa; Park, Jun-Seong; Kim, Duck-Hee; Kim, Do-Won; Ahn, Sul-Ah; Sunwoo, Changshin; Kim, Doman

doi:10.1016/j.enzmictec.2011.09.007

[해외논문] Glucosylation of the flavonoid, astragalin by Leuconostoc mesenteroides B-512FMCM dextransucrase acceptor reactions and characterization of the products

Enzyme and microbial technology, v.50 no.1, 2012년, pp.50 - 56

Kim, Go-Eun (Interdisciplinary Program of Graduate School for Bioenergy and Biomaterials, Chonnam National University, Gwangju, 500-757 Republic of Korea) , Kang, Hee-Kyoung (School of Biological Sciences and Technology and the Research Institute for Catalysis, Chonnam National University, Gwangju, 500-757 Republic of Korea) , Seo, Eun-Seong (School of Biological Sciences and Technology and the Research Institute for Catalysis, Chonnam National University, Gwangju, 500-757 Republic of Korea) , Jung, Sun-Hwa (Interdisciplinary Program of Graduate School for Bioenergy and Biomaterials, Chonnam National University, Gwangju, 500-757 Republic of Korea) , Park, Jun-Seong (Skin Research Institute, AmorePacific R&D Center, 314-1, Bora-dong, Giheung-gu, Yongin, Gyeonggido, 449-729, Republic of Korea) , Kim, Duck-Hee (Skin Research Institute, AmorePacific R&D Center, 314-1, Bora-dong, Giheung-gu, Yongin, Gyeonggido, 449-729, Republic of Korea) , Kim, Do-Won (Department of Physics, Gangneung-Wonju National University, Gangneung, 210-702, Republic of Korea) , Ahn, Sul-Ah (Global Science Experimental Data Hub Center, Korea) , Sunwoo, Changshin , Kim, Doman

Abstract ▼ AI-Helper

Graphical abstract AbstractAstragalin (kaempferol-3-O-β-D-glucopyranoside, Ast) glucosides were synthesized by the acceptor reaction of a dextransucrase produced by Leuconostoc mesenteroides B-512FMCM with astragalin and sucrose. Each glucoside was purified and their structures were assigned as kaempferol-3-O-β-D-glucopyranosyl-(1→3)-O-α-D-glucopyranoside (or kaempferol-3-O-β-D-nigeroside, Ast-G1′) and kaempferol-3-O-β-D-glucopyranosyl-(1→6)-O-α-D-glucopyranoside (or kaempferol-3-O-β-D-isomaltoside, Ast-G1) for one glucose transferred, and kaempferol-3-O-β-D-isomaltooligosacharide (Ast-IMO or Ast-Gn; n=2–8). The astragalin glucosides exhibited 8.3–60.6% higher inhibitory effects on matrix metalloproteinase-1 expression, 18.8–20.3% increased antioxidant effects, and 3.8–18.8% increased inhibition activity of melanin synthesis compared to control (without the addition of compound), depending on the number of glucosyl residues linked to astragalin. These novel compounds could be used to further expand the industrial applications of astragalin glucosides, in particular in the cosmetics industry.

Keyword

참고문헌 (32)

Donald RB, Miranda C. Antioxidant activities of flavonoids. Available from: http://lpioregonstateedu/f-w00/flavonoidhtml 2000.
Free Radic Biol Med Rice-Evans 20 933 1996 10.1016/0891-5849(95)02227-9 Structure-antioxydant activity relationship of flavonoids and phenolics acids

상세보기
Carbohydr Res Robyt 343 3039 2008 10.1016/j.carres.2008.09.012 Dextransucrase and the mechanism for dextran biosynthesis

상세보기
Adv Carbohydr Chem Biochem Robyt 51 133 1995 10.1016/S0065-2318(08)60193-6 Mechanisms in the glucansucrase synthesis of polysaccharides and oligosaccharides from sucrose

상세보기
J Biol Chem Koepesell 200 793 1953 10.1016/S0021-9258(18)71427-0 Enzymatic synthesis of dextran; acceptor specificity and chain initiation

상세보기
J Biotechnol Seo 117 31 2005 10.1016/j.jbiotec.2004.10.013 Enzymatic synthesis and anti-coagulant effect of salicin analogous by using the Leuconostoc mesenteroides glucansucrase acceptor reaction

상세보기
Appl Microbiol Biotechnol Kang 83 1009 2009 10.1007/s00253-009-1936-5 Synthesis and characterization of hydroquinone fructoside using Leuconostoc mesenteroides levansucrase

상세보기
Enzyme Microb Technol Seo 45 355 2009 10.1016/j.enzmictec.2009.07.011 Synthesis and characterization of hydroquinone glucoside using Leuconostoc mesenteroides dextransucrase

상세보기
J Agric Food Chem Kim 58 9492 2010 10.1021/jf101748j Enzymatic synthesis and characterization of hydroquinone galactoside using Kluyveromyces lactis lactase

상세보기
J Agric Food Chem Moon 54 1230 2006 10.1021/jf052359i Synthesis, structure analyses, and characterization of novel epigallocatechin gallate (EGCG) glycosides using the glucansucrase from Leuconostoc mesenteroides B-1299CB

상세보기
Enzyme Microb Technol Moon 40 1124 2007 10.1016/j.enzmictec.2006.08.019 Synthesis and characterization of novel quercetin-alpha-d-glucopyranosides using glucansucrase from Leuconostoc mesenteroides

상세보기
Biosci Biotechnol Biochem Shimizu 70 940 2006 10.1271/bbb.70.940 Enzymatic production of highly soluble myricitrin glycosides using beta-galactosidase

상세보기
Yamamoto 399 2000 Hydrocolloids (Part II) Hypercholesterolemic effects of levan in rat
Am J Clin Nutr de Roos 71 405 2000 10.1093/ajcn/71.2.405 Effects of probiotic bacteria on diarrhea, lipid metabolism, and carcinogenesis: a review of papers published between 1988 and 1998

상세보기
Arch Biochem Biophys Murota 501 91 2010 10.1016/j.abb.2010.06.036 alpha-Oligoglucosylation of a sugar moiety enhances the bioavailability of quercetin glucosides in humans

상세보기
Phytochemistry Nielsen 49 2171 1998 10.1016/S0031-9422(98)00422-1 Kaempferol tetraglucosides from cabbage leaves

상세보기
J Agric Food Chem Parejo 52 1890 2004 10.1021/jf030717g Bioguided isolation and identification of a nonvolatile antioxidant compounds from fennel (Foeniculum vulgare Mill.) waste

상세보기
Biomed Chromatogr Correia 20 88 2006 10.1002/bmc.533 Polyphenolic profile characterization of Agrimonia eupatoria L. by HPLC with different detection devices

상세보기
J Nat Prod Schinazi 60 884 1997 10.1021/np9700275 In vitro anti-HIV activity of biflavonoids isolated from Rhus succedanea and Garcinia multiflora

상세보기
Br J Dermatol Matsumoto 146 221 2002 10.1046/j.1365-2133.2002.04557.x Oral administration of persimmon leaf extract ameliorates skin symptoms and transepidermal water loss in atopic dermatitis model mice, NC/Nga

상세보기
J Agric Food Chem Beninger 47 4079 1999 10.1021/jf990440d Flavonol glycosides from Montcalm dark red kidney bean: implications for the genetics of seed coat color in Phaseolus vulgaris L.

상세보기
Biotechnol Tech Kim 11 319 1997 10.1023/A:1018471429067 Development of constitutive dextransucrase hyper-producing mutant of Leuconstoc mesenteroides using the synchrotron radiation in the 70-1000eV region

상세보기
J Microbiol Biotechnol Kim 9 219 1999 Facile purification and characterization of dextransucrase from Leuconostoc mesenteroides B-512 FMCM

원문보기 상세보기
Curr Opin Cell Biol McCawley 13 534 2001 10.1016/S0955-0674(00)00248-9 Matrix metalloproteinases: they are not just for matrix anymore

상세보기
Semin Cancer Biol Stetler-Stevenson 11 143 2001 10.1006/scbi.2000.0365 Proteases in invasion: matrix metalloproteinases

상세보기
Eur J Haematol Amer 70 84 2003 10.1034/j.1600-0609.2003.00011.x Flow cytometric measurement of reactive oxygen species production by normal and thalassaemic red blood cells

상세보기
J Biochem Biophys Methods Aroca 19 327 1989 10.1016/0165-022X(89)90064-X A reexamination of the melanin formation assay of tyrosinase and an extension to estimate phaeomelanin formation

상세보기
Anal Biochem Kalb 82 362 1977 10.1016/0003-2697(77)90173-7 A new spectrophotometric assay for protein in cell extracts

상세보기
Agrawal 1989 Carbon-13 NMR of Flavonoids Flavonoid glycosides
Biosci Biotechnol Biochem Chiku 73 1123 2009 10.1271/bbb.80885 Enzymatic synthesis of 4-hydroxyphenyl beta-d-oligoxylosides and their notable tyrosinase inhibitory activity

상세보기
Int J Biochem Cell Biol Valko 39 44 2007 10.1016/j.biocel.2006.07.001 Free radicals and antioxidants in normal physiological functions and human disease

상세보기
Exp Gerontol Passos 40 466 2005 10.1016/j.exger.2005.04.006 Mitochondria, telomeres and cell senescence

상세보기

LOADING...

활용도 분석정보

상세보기

다운로드

내보내기

활용도 Top5 논문

해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

[해외논문] Glucosylation of the flavonoid, astragalin by Leuconostoc mesenteroides B-512FMCM dextransucrase acceptor reactions and characterization of the products

Abstract ▼ AI-Helper

Keyword

참고문헌 (32)

이 논문을 인용한 문헌

연구과제 타임라인

활용도 분석정보

활용도 Top5 논문

관련 콘텐츠

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

[해외논문] Glucosylation of the flavonoid, astragalin by Leuconostoc mesenteroides B-512FMCM dextransucrase acceptor reactions and characterization of the products

Abstract ▼ AI-Helper

Keyword

참고문헌 (32)

이 논문을 인용한 문헌

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

활용도 분석정보

활용도 Top5 논문 더보기

관련 콘텐츠

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

활용도 Top5 논문