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Archiv für dermatologische Forschung, v.249 no.2, 1974년, pp.99 - 104
Blumenkrantz, N. , Asboe-Hansen, G.
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SummaryThe biosynthess of collagen and elastin by chick embryo skin of 11–16 days of development was studied. An increased uptake of (14C) proline and (14C) lysine on day 12 was observed in collagen peptides and in elastin extracted from the skin samples.(14C)hydroxyproline followed the same p...
ZusammenfassungDie Kollagen- und Elastinbiosynthese in 11–16 Tage alter Hühnchenhaut wurde untersucht. Am 12. Tag zeigte sich eine erhöhte Aufnahme von14C-Prolin und C14-Lysin in Kollagenpeptide und Elastin, die aus den Hautpräparaten isoliert wurden. C14-Hydroxyprolin zeigte ein gleiches Muster des Einbaues in die kollagenase-verdauliche Peptidfraktion. Die Konversion von14C-Lysin in14C-Hydroxylysin war gering. Der Übergang von C14-Glutaminsäure und C14-Glutamin in14C-Prolin und14C-Hydroxyprolin in der Hühnchenhaut ist möglicherweise eine wichtige Route. Elastin zeigte hinsichtlich C14-Prolin und C14-Lysin während des Reifungsprozesses ein ähnliches Einbauverhalten.
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