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Materials science & engineering. C, Materials for biological applications, v.32 no.7, 2012년, pp.2037 - 2041
Silvestri, Brigida (Department of Materials and Production Engineering, University of Naples Federico II, 80125, Naples, Italy) , Pezzella, Alessandro (Department of Organic Chemistry and Biochemistry, University of Naples Federico II, 80126, Naples, Italy) , Luciani, Giuseppina (Department of Materials and Production Engineering, University of Naples Federico II, 80125, Naples, Italy) , Costantini, Aniello (Department of Materials and Production Engineering, University of Naples Federico II, 80125, Naples, Italy) , Tescione, Fabiana (Department of Materials and Production Engineering, University of Naples Federico II, 80125, Naples, Italy) , Branda, Francesco (Department of Materials and Production Engineering, University of Naples Federico II, 80125, Naples, Italy)
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Abstract We report on a facile method towards a synthesis of novel hybrid heparin silica nanoparticles involving a modification of the Stober method. Tetrapropyl orthosilicate (TPOS) was used instead of the traditional TEOS or TMOS; by this way we could overcome the solubility problems of heparin i...
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