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High throughput identification and quantification of 16 antipsychotics and 8 major metabolites in serum using ultra-high performance liquid chromatography-tandem mass spectrometry

Clinica chimica acta, v.429, 2014년, pp.51 - 58  

Patteet, L. ,  Maudens, K.E. ,  Sabbe, B. ,  Morrens, M. ,  De Doncker, M. ,  Neels, H.

Abstract AI-Helper 아이콘AI-Helper

Background: Therapeutic drug monitoring of antipsychotics is important for optimizing therapy, explaining adverse effects, non-response or poor compliance. We developed a UHPLC-MS/MS method for quantification of 16 commonly used and recently marketed antipsychotics and 8 metabolites in serum. Method...

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