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Toxicology in vitro : an international journal published in association with BIBRA, v.45 pt.1, 2017년, pp.172 - 180
Liu, Xuemei (Corresponding author at: Preclinical Safety, Alcon Research, Ltd., 6201 South Freeway, Fort Worth, TX 76134, United States.) , Zhang, Fan , Rodeheaver, Denise , Wright, Ann , Tolliver, Charlon , Walker, Jamie , Rose, Robert
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Abstract We describe a new, quantitative, cytotoxicity method using mouse lymphoma L5178Y thymidine kinase+/− (TK) suspension cells for medical device safety assessment that has equivalent sensitivity, and greater efficiency compared to the colony formation assay (CFA) using adherent V79-4 ce...
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