$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Topical drug delivery to retinal pigment epithelium with microfluidizer produced small liposomes

European journal of pharmaceutical sciences, v.62, 2014년, pp.23 - 32  

Lajunen, T. ,  Hisazumi, K. ,  Kanazawa, T. ,  Okada, H. ,  Seta, Y. ,  Yliperttula, M. ,  Urtti, A. ,  Takashima, Y.

Abstract AI-Helper 아이콘AI-Helper

Drug delivery from topically instilled eye drops to the posterior segment of the eye has long been one of the greatest challenges of ocular drug development. We developed methods of liposome preparation utilizing a microfluidizer to achieve adjustable nanoparticle size (even less than 80nm) and high...

주제어

참고문헌 (55)

  1. Biochim. Biophys. Acta (BBA)-Biomembr. Allen 1066 29 1991 10.1016/0005-2736(91)90246-5 Liposomes containing synthetic lipid derivatives of poly (ethylene glycol) show prolonged circulation half-lives in vivo 

  2. Biochim. Biophys. Acta (BBA)-Biomembr. Bailey 1468 239 2000 10.1016/S0005-2736(00)00264-9 Efficient encapsulation of DNA plasmids in small neutral liposomes induced by ethanol and calcium 

  3. Ophthalmology Bakri 114 855 2007 10.1016/j.ophtha.2007.01.017 Pharmacokinetics of intravitreal bevacizumab (Avastin) 

  4. J. Mol. Biol. Bangham 13 238 1965 10.1016/S0022-2836(65)80093-6 Diffusion of univalent ions across the lamellae of swollen phospholipids 

  5. J. Colloid Interface Sci. Bergstrom 293 181 2006 10.1016/j.jcis.2005.06.050 Model calculations of the spontaneous curvature, mean and Gaussian bending constants for a thermodynamically open surfactant film 

  6. Microsc. Res. Tech. Beuerman 33 320 1996 10.1002/(SICI)1097-0029(19960301)33:4<320::AID-JEMT3>3.0.CO;2-T Ultrastructure of the human cornea 

  7. J. Controlled Release Bodmeier 12 223 1990 10.1016/0168-3659(90)90103-Z Indomethacin polymeric nanosuspensions prepared by microfujidization 

  8. J. Anat. Cavallotti 206 243 2005 10.1111/j.1469-7580.2005.00389.x The human choriocapillaris: evidence for an intrinsic regulation of the endothelium? 

  9. Invest. Ophthalmol. Vis. Sci. Chowers 47 2135 2006 10.1167/iovs.05-1135 The iron carrier transferrin is upregulated in retinas from patients with age-related macular degeneration 

  10. Small Davis 10 1575 2014 10.1002/smll.201303433 Topical delivery of avastin to the posterior segment of the eye in vivo using annexin A5-associated liposomes 

  11. Drug Discov. Today Del Amo 13 135 2008 10.1016/j.drudis.2007.11.002 Current and future ophthalmic drug delivery systems: a shift to the posterior segment 

  12. Invest. Ophthalmol. Vis. Sci. Enriquez de Salamanca 47 1416 2006 10.1167/iovs.05-0495 Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance 

  13. Biochim. Biophys. Acta (BBA)-Biomembr. Even-Chen 1509 176 2000 10.1016/S0005-2736(00)00292-3 DOTAP cationic liposomes prefer relaxed over supercoiled plasmids 

  14. Forrester 2008 The Eye: Basic Sciences in Practice 

  15. Invest. Ophthalmol. Vis. Sci. Guymer 45 1660 2004 10.1167/iovs.03-0913 Cytoarchitecture of choroidal capillary endothelial cells 

  16. Int. J. Pharm. Hatakeyama 281 25 2004 10.1016/j.ijpharm.2004.05.025 Factors governing the in vivo tissue uptake of transferrin-coupled polyethylene glycol liposomes in vivo 

  17. Pharm. Res. Horibe 14 1246 1997 10.1023/A:1012123411343 Polar solute transport across the pigmented rabbit conjunctiva: size dependence and the influence of 8-bromo cyclic adenosine monophosphate 

  18. J. Pharm. Sci. Huang 72 1272 1983 10.1002/jps.2600721109 Corneal penetration behavior of beta-blocking agents II: assessment of barrier contributions 

  19. Adv. Drug Deliv. Rev. Hughes 57 2010 2005 10.1016/j.addr.2005.09.004 Topical and systemic drug delivery to the posterior segments 

  20. Invest. Ophthalmol. Vis. Sci. Hamalainen 38 627 1997 Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera 

  21. J. Pharm. Pharmacol. Kawakami 53 1157 2001 10.1211/0022357011776423 Sustained ocular delivery of tilisolol to rabbits after topical administration or intravitreal injection of lipophilic prodrug incorporated in liposomes 

  22. Pharm. Res. Kidron 29 3302 2012 10.1007/s11095-012-0822-5 Prediction of the vitreal half-life of small molecular drug-like compounds 

  23. Exp. Eye Res. Kim 82 760 2006 10.1016/j.exer.2005.09.018 The pharmacokinetics of rituximab following an intravitreal injection 

  24. Pharm. Pharmacol. Commun. Kompella 4 339 1998 Effect of liposomal charge on stavudine transport across rabbit cornea and conjunctiva 

  25. Krachmer 2011 Cornea 

  26. J. Controlled Release Law 63 135 2000 10.1016/S0168-3659(99)00192-3 Acyclovir-containing liposomes for potential ocular delivery: corneal penetration and absorption 

  27. Int. J. Food Prop. Mahdi Jafari 9 475 2006 10.1080/10942910600596464 Nano-emulsion production by sonication and microfluidization-a comparison 

  28. J. Ocul. Pharmacol. Ther. Mains 29 143 2013 10.1089/jop.2012.0138 The vitreous humor as a barrier to nanoparticle distribution 

  29. Invest. Ophthalmol. Vis. Sci. Masuda 37 1914 1996 Gene transfer with liposomes to the intraocular tissues by different routes of administration 

  30. Surv. Ophthalmol. Maurice 47 41 2002 10.1016/S0039-6257(02)00326-0 Drug delivery to the posterior segment from drops 

  31. Maurice 19 1984 Anonymous Pharmacology of the Eye Ocular pharmacokinetics 

  32. Biochim. Biophys. Acta (BBA)-Biomembr. Mayhew 775 169 1984 10.1016/0005-2736(84)90167-6 Characterization of liposomes prepared using a microemulsifier 

  33. Toxicol. Sci. Mordenti 52 101 1999 10.1093/toxsci/52.1.101 Intraocular pharmacokinetics and safety of a humanized monoclonal antibody in rabbits after intravitreal administration of a solution or a PLGA microsphere formulation 

  34. Acta Biomater. Nagai 10 680 2014 10.1016/j.actbio.2013.11.004 A polymeric device for controlled transscleral multi-drug delivery to the posterior segment of the eye 

  35. Langmuir Pautot 19 2870 2003 10.1021/la026100v Production of unilamellar vesicles using an inverted emulsion 

  36. Br. J. Ophthalmol. Prager 93 452 2009 10.1136/bjo.2008.141085 Intravitreal bevacizumab (Avastin) for macular oedema secondary to retinal vein occlusion: 12-month results of a prospective clinical trial 

  37. J. Controlled Release Ranta 148 42 2010 10.1016/j.jconrel.2010.08.028 Barrier analysis of periocular drug delivery to the posterior segment 

  38. Int. J. Pharm. Saheki 422 489 2012 10.1016/j.ijpharm.2011.10.060 Effect of back pressure on emulsification of lipid nanodispersions in a high-pressure homogenizer 

  39. J. Microencapsul. Sani 26 556 2009 10.1080/02652040802500655 Effect of microfluidization parameters on the physical properties of PEG-PLGA nanoparticles prepared using high pressure microfluidization 

  40. Langmuir Siqueira 26 402 2009 10.1021/la9028595 New process of chemical grafting of cellulose nanoparticles with a long chain isocyanate 

  41. Int. J. Pharm. Sorgi 144 131 1996 10.1016/S0378-5173(96)04733-3 Large scale production of DC-Chol cationic liposomes by microfluidization 

  42. Cell Struct. Funct. Sugasawa 19 21 1994 10.1247/csf.19.21 Immunocytochemical analyses of distributions of Na, K-ATPase and GLUT1, insulin and transferrin receptors in the developing retinal pigment epithelial cells 

  43. Jpn. J. Ophthalmol. Sugita 26 47 1982 Regional difference in fenestration of choroidal capillaries in Japanese monkey eye 

  44. J. Oleo Sci. Takahashi 58 643 2009 10.5650/jos.58.643 Liposomes encapsulating Aloe vera leaf gel extract significantly enhance proliferation and collagen synthesis in human skin cell lines 

  45. Int. J. Pharm. Takashima 343 262 2007 10.1016/j.ijpharm.2007.05.042 Spray-drying preparation of microparticles containing cationic PLGA nanospheres as gene carriers for avoiding aggregation of nanospheres 

  46. J. Dairy Sci. Thompson 89 410 2006 10.3168/jds.S0022-0302(06)72105-1 Preparation of liposomes from milk fat globule membrane phospholipids using a microfluidizer 

  47. Adv. Drug Deliv. Rev. Urtti 58 1131 2006 10.1016/j.addr.2006.07.027 Challenges and obstacles of ocular pharmacokinetics and drug delivery 

  48. Int. J. Pharm. Urtti 61 241 1990 10.1016/0378-5173(90)90215-P Controlled drug delivery devices for experimental ocular studies with timolol 2. Ocular and systemic absorption in rabbits 

  49. Vascul. Pharmacol. Voinea 39 13 2002 10.1016/S1537-1891(02)00165-9 Binding and uptake of transferrin-bound liposomes targeted to transferrin receptors of endothelial cells 

  50. Invest. Ophthalmol. Vis. Sci. Wang 53 7348 2012 10.1167/iovs.12-9955 EphA2 targeted doxorubicin stealth liposomes as a therapy system for choroidal neovascularization in rats 

  51. Int. J. Pharm. Washington 44 169 1988 10.1016/0378-5173(88)90113-5 The production of parenteral feeding emulsions by microfluidizer 

  52. Langmuir Whittenton 24 8533 2008 10.1021/la801133j Evaluation of asymmetric liposomal nanoparticles for encapsulation of polynucleotides 

  53. Invest. Ophthalmol. Vis. Sci. Yefimova 41 2343 2000 Iron, ferritin, transferrin, and transferrin receptor in the adult rat retina 

  54. Int. J. Pharm. Ying 453 329 2013 10.1016/j.ijpharm.2013.06.024 Drug delivery to the ocular posterior segment using lipid emulsion via eye drop administration: effect of emulsion formulations and surface modification 

  55. Soft Matter Zook 6 1352 2010 10.1039/b923299k Effects of temperature, acyl chain length, and flow-rate ratio on liposome formation and size in a microfluidic hydrodynamic focusing device 

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로