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[해외논문] Analysis of gene profiles involved in the enhancement of all-trans retinoic acid-induced HL-60 cell differentiation by sesquiterpene lactones identifies asparagine synthetase as a novel target for differentiation-inducing therapy 원문보기

International journal of oncology, v.44 no.3, 2014년, pp.970 - 976  

SONG, JU HAN ,  KIM, SEUNG HYUN ,  CHO, KYUNG-MIN ,  HWANG, SEUNG YONG ,  KIM, HYEOUNG-JOON ,  KIM, TAE SUNG

Abstract AI-Helper 아이콘AI-Helper

All-trans retinoic acid (ATRA) is one of the most useful drugs in the treatment for acute promyelocytic leukemia (APL), but its adverse effects, which include drug resistance and hypercalcemia are obstacles to achieving complete remission. Our previous study showed that some sesquiterpene lactones (...

참고문헌 (36)

  1. Proc Natl Acad Sci USA Breitman 77 2936 1980 10.1073/pnas.77.5.2936 Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid 

  2. Blood Breitman 57 1000 1981 10.1182/blood.V57.6.1000.1000 Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid 

  3. Blood Flynn 62 1211 1983 10.1182/blood.V62.6.1211.1211 Retinoic acid treatment of acute promyelocytic leukemia: in vitro and in vivo observations 

  4. Blood Huang 72 567 1988 10.1182/blood.V72.2.567.567 Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia 

  5. Mol Cell Biol Collins 10 2154 1990 10.1128/MCB.10.5.2154 Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha) 

  6. EMBO J Duprez 22 5806 2003 10.1093/emboj/cdg556 C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells 

  7. Blood Matikainen 88 114 1996 10.1182/blood.V88.1.114.114 Retinoic acid activates interferon regulatory factor-1 gene expression in myeloid cells 

  8. Leuk Lymphoma Bennett 46 1829 2005 10.1080/10428190500235298 Hypercalcemia due to all trans retinoic acid in the treatment of acute promyelocytic leukemia potentiated by voriconazole 

  9. Blood Imaizumi 92 374 1998 10.1182/blood.V92.2.374 Mutations in the E-domain of RAR portion of the PML/RAR chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia 

  10. Blood Montesinos 113 775 2009 10.1182/blood-2008-07-168617 Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: characteristics, outcome, and prognostic factors 

  11. Blood Shao 89 4282 1997 10.1182/blood.V89.12.4282 A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation 

  12. Crit Rev Oncol Hematol Lengfelder 56 261 2005 10.1016/j.critrevonc.2004.08.009 Treatment concepts of acute promyelocytic leukemia 

  13. J Immunol Hehner 163 5617 1999 10.4049/jimmunol.163.10.5617 The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex 

  14. Biochem Biophys Res Commun Sobota 267 329 2000 10.1006/bbrc.1999.1948 Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family 

  15. Int J Cancer Oka 120 2576 2007 10.1002/ijc.22570 Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappaB 

  16. Cancer Genomics Proteomics Sohma 8 39 2011 Parthenolide, an NF-κB inhibitor, suppresses tumor growth and enhances response to chemotherapy in gastric cancer 

  17. Biochem Pharmacol Hoffmann 82 453 2011 10.1016/j.bcp.2011.05.029 Helenalin bypasses Bcl-2-mediated cell death resistance by inhibiting NF-κB and promoting reactive oxygen species generation 

  18. J Ethnopharmacol Kassuya 124 369 2009 10.1016/j.jep.2009.06.003 Antipyretic and anti-inflammatory properties of the ethanolic extract, dichloromethane fraction and costunolide from Magnolia ovata (Magnoliaceae) 

  19. J Biol Chem Lyss 273 33508 1998 10.1074/jbc.273.50.33508 The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65 

  20. Molecules Rasul 18 1418 2013 10.3390/molecules18021418 Induction of apoptosis by costunolide in bladder cancer cells is mediated through ROS generation and mitochondrial dysfunction 

  21. Phytother Res Ferrari 27 384 2013 10.1002/ptr.4736 Anti-inflammatory sesquiterpene lactones from Lychnophora trichocarpha Spreng. (Brazilian Arnica) 

  22. Planta Med Kretschmer 78 1749 2012 10.1055/s-0032-1315385 Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells 

  23. J Ethnopharmacol Piornedo Rdos 133 1077 2011 10.1016/j.jep.2010.11.040 Anti-inflammatory activity of extracts and 11,13-dihydrozaluzanin C from Gochnatia polymorpha ssp floccosa trunk bark in mice 

  24. Proc Natl Acad Sci USA Collins 75 2458 1978 10.1073/pnas.75.5.2458 Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds 

  25. Biochem Biophys Res Commun Tanaka 117 86 1983 10.1016/0006-291X(83)91544-9 1 alpha,25-dihydroxyvitamin D3 induces differentiation of human promyelocytic leukemia cells (HL-60) into monocytemacrophages, but not into granulocytes 

  26. Br J Pharmacol Kim 155 814 2008 10.1038/bjp.2008.319 Differential enhancement of leukaemia cell differentiation without elevation of intracellular calcium by plant-derived sesquiterpene lactone compounds 

  27. Int J Oncol Song 29 57 2006 Identification of gene expression signatures for molecular classification in human leukemia cells 

  28. J Biol Chem Pan 278 38402 2003 10.1074/jbc.M304574200 Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple activating transcription factor-3 mRNA species that, when over-expressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter 

  29. Blood Rousseau 118 5883 2011 10.1182/blood-2011-05-355560 ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia 

  30. Br J Pharmacol Kang 135 1235 2002 10.1038/sj.bjp.0704573 Enhancement of 1 alpha,25-dihydroxyvitamin D(3)-induced differentiation of human leukaemia HL-60 cells into monocytes by parthenolide via inhibition of NF-kappa B activity 

  31. Chem Biol Gutierrez 13 1339 2006 10.1016/j.chembiol.2006.10.010 An inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line 

  32. Mol Cancer Ther Lorenzi 5 2613 2006 10.1158/1535-7163.MCT-06-0447 Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells 

  33. N Engl J Med Clavell 315 657 1986 10.1056/NEJM198609113151101 Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia 

  34. Cancer Res Ortega 37 535 1977 L-Asparaginase, vincristine, and prednisone for induction of first remission in acute lymphocytic leukemia 

  35. Leukemia Hongo 4 708 1990 Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines 

  36. Anticancer Res Hashimoto 29 1303 2009 Declined asparagine synthetase mRNA expression and enhanced sensitivity to asparaginase in HL-60 cells committed to monocytic differentiation 

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