Lim, Young-Hyo
(Division of Cardiology, Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea)
,
Choi, Jihye
(Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Korea)
,
Kim, Kyung Rae
(Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Korea)
,
Shin, Jinho
(Division of Cardiology, Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea)
,
Hwang, Kyung Gyun
(Department of Dentistry, College of Medicine, Hanyang University, Seoul, Korea)
,
Ryu, Seungho
(Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea)
,
Cho, Seok Hyun
(Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Korea)
Objective: This study aimed to investigate the sex-specific effects of anthropometric profiles on the occurrence and severity of obstructive sleep apnea (OSA). Methods: We evaluated 151 patients with suspected OSA undergoing polysomnography and anthropometric measurements such as body mass index (BM...
Objective: This study aimed to investigate the sex-specific effects of anthropometric profiles on the occurrence and severity of obstructive sleep apnea (OSA). Methods: We evaluated 151 patients with suspected OSA undergoing polysomnography and anthropometric measurements such as body mass index (BMI), neck and waist circumference (NC and WC), and waist-hip ratio (WHR). Results: In men, NC ( P = .006), WC ( P = .035), and WHR ( P = .003) were significantly increased in OSA and all were significantly correlated with apnea hypopnea index (AHI). However, in female OSA patients, BMI ( P = .05), WC ( P = .008), and WHR ( P = .001) were elevated, but only WHR was significantly correlated with AHI. Correlation analyses showed significant correlations between NC and other anthropometric indexes in men but not in women. The receiver operating characteristic curves revealed that NC and WHR in men, and WHR in women, were significant in both model 1 (AHI ≥ 5) and model 2 (AHI ≥ 15). Conclusion: Waist-hip ratio is the most reliable correlate of OSA in both sexes. Neck circumference is an independent risk factor for male, but not for female, OSA patients. These different aspects of obesity may contribute to the pathogenesis of OSA and provide helpful guidance in the screening of OSA.
Objective: This study aimed to investigate the sex-specific effects of anthropometric profiles on the occurrence and severity of obstructive sleep apnea (OSA). Methods: We evaluated 151 patients with suspected OSA undergoing polysomnography and anthropometric measurements such as body mass index (BMI), neck and waist circumference (NC and WC), and waist-hip ratio (WHR). Results: In men, NC ( P = .006), WC ( P = .035), and WHR ( P = .003) were significantly increased in OSA and all were significantly correlated with apnea hypopnea index (AHI). However, in female OSA patients, BMI ( P = .05), WC ( P = .008), and WHR ( P = .001) were elevated, but only WHR was significantly correlated with AHI. Correlation analyses showed significant correlations between NC and other anthropometric indexes in men but not in women. The receiver operating characteristic curves revealed that NC and WHR in men, and WHR in women, were significant in both model 1 (AHI ≥ 5) and model 2 (AHI ≥ 15). Conclusion: Waist-hip ratio is the most reliable correlate of OSA in both sexes. Neck circumference is an independent risk factor for male, but not for female, OSA patients. These different aspects of obesity may contribute to the pathogenesis of OSA and provide helpful guidance in the screening of OSA.
참고문헌 (33)
Young, Terry, Palta, Mari, Dempsey, Jerome, Skatrud, James, Weber, Steven, Badr, Safwan.
The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults.
The New England journal of medicine,
vol.328,
no.17,
1230-1235.
Levy, P., Bonsignore, M. R., Eckel, J..
Sleep, sleep-disordered breathing and metabolic consequences.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology,
vol.34,
no.1,
243-260.
Coughlin, S.
Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome.
European heart journal,
vol.25,
no.9,
735-741.
Doherty, Liam S., Kiely, John L., Swan, Valerie, McNicholas, Walter T..
Long-term Effects of Nasal Continuous Positive Airway Pressure Therapy on Cardiovascular Outcomes in Sleep Apnea Syndrome.
Chest : official publication of the American College of Chest Physicians,
vol.127,
no.6,
2076-2084.
Villaneuva, Anna Tessa C., Buchanan, Peter R., Yee, Brendon J., Grunstein, Ronald R..
Ethnicity and obstructive sleep apnoea.
Sleep medicine reviews,
vol.9,
no.6,
419-436.
Onat, Altan, Hergenç, Gülay, Yüksel, Hüsniye, Can, Günay, Ayhan, Erkan, Kaya, Zekeriya, Dursunoğlu, Dursun.
Neck circumference as a measure of central obesity: Associations with metabolic syndrome and obstructive sleep apnea syndrome beyond waist circumference.
Clinical nutrition : official journal of the European Society of Parenteral and Enteral Nutrition,
vol.28,
no.1,
46-51.
Vgontzas, Alexandros N..
Does obesity play a major role in the pathogenesis of sleep apnoea and its associated manifestations via inflammation, visceral adiposity, and insulin resistance?.
Archives of physiology and biochemistry,
vol.114,
no.4,
211-223.
Young, Terry, Shahar, Eyal, Nieto, F Javier, Redline, Susan, Newman, Anne B, Gottlieb, Daniel J, Walsleben, Joyce A, Finn, Laurel, Enright, Paul, Samet, Jonathan M.
Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study..
Archives of internal medicine,
vol.162,
no.8,
893-900.
Berry, Richard B., Budhiraja, Rohit, Gottlieb, Daniel J., Gozal, David, Iber, Conrad, Kapur, Vishesh K., Marcus, Carole L., Mehra, Reena, Parthasarathy, Sairam, Quan, Stuart F., Redline, Susan, Strohl, Kingman P., Ward, Sally L. Davidson, Tangredi, Michelle M..
Rules for Scoring Respiratory Events in Sleep: Update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events : Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine,
vol.8,
no.5,
597-619.
Deegan, PC, McNicholas, WT.
Predictive value of clinical features for the obstructive sleep apnoea syndrome.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology,
vol.9,
no.1,
117-124.
SHINOHARA, E., KIHARA, S., YAMASHITA, S., YAMANE, M., NISHIDA, M., ARAI, T., KOTANI, K., NAKAMURA, T., TAKEMURA, K., MATSUZAWA, Y..
Visceral fat accumulation as an important risk factor for obstructive sleep apnoea syndrome in obese subjects.
Journal of internal medicine,
vol.241,
no.1,
11-18.
Chung, Seockhoon, Yoon, In-Young, Shin, Yoon-Kyung, Lee, Chul Hee, Kim, Jeong-Whun, Lee, Taeseung, Choi, Dong-Ju, Jeong Ahn, Hee.
Endothelial Dysfunction and C-Reactive Protein in Relation with the Severity of Obstructive Sleep Apnea Syndrome.
Sleep : Journal of sleep and sleep disorders research,
vol.30,
no.8,
997-1001.
Martinez‐Rivera, Carlos, Abad, Jorge, Fiz, Jose A., Rios, Jose, Morera, Josep.
Usefulness of Truncal Obesity Indices as Predictive Factors for Obstructive Sleep Apnea Syndrome.
Obesity,
vol.16,
no.1,
113-118.
Whittle, A. T, Marshall, I., Mortimore, I. L, Wraith, P. K, Sellar, R. J, Douglas, N. J.
Neck soft tissue and fat distribution: comparison between normal men and women by magnetic resonance imaging.
Thorax,
vol.54,
no.4,
323-328.
Simpson, Laila, Mukherjee, Sutapa, Cooper, Matthew N., Ward, Kim L., Lee, Jessica D., Fedson, Annette C., Potter, Jane, Hillman, David R., Eastwood, Peter, Palmer, Lyle J., Kirkness, Jason.
Sex Differences in the Association of Regional Fat Distribution with the Severity of Obstructive Sleep Apnea.
Sleep : Journal of sleep and sleep disorders research,
vol.33,
no.4,
467-474.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.