$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Monoclonal Antibodies against Vibrio vulnificus RtxA1 Elicit Protective Immunity through Distinct Mechanisms 원문보기

Infection and immunity, v.82 no.11, 2014년, pp.4813 - 4823  

Lee, Tae Hee (Department of Microbiology and Immunology, Chonbuk National University Medical School, Jeonju, Jeonbuk, South Korea) ,  Cha, Sun-Shin (Marine Biotechnology Research Division, Korea Institute of Ocean Science and Technology, Ansan, South Korea) ,  Lee, Chang-Seop (Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Jeonbuk, South Korea) ,  Rhee, Joon Haeng (Department of Microbiology and Clinical Vaccine R&D Center, Chonnam National University Medical School, Gwangju, South Korea) ,  Chung, Kyung Min (Department of Microbiology and Immunology, Chonbuk National University Medical School, Jeonju, Jeonbuk, South Korea)

Abstract AI-Helper 아이콘AI-Helper

Vibrio vulnificus causes rapidly progressing septicemia with an extremely high mortality rate (≥50%), even with aggressive antibiotic treatment. The bacteria secrete multifunctional autoprocessing repeats-in-toxin (MARTX) toxins, which are involved in the pathogenesis of Gram-negative Vibrio ...

참고문헌 (61)

  1. Baffone, Wally, Tarsi, Renato, Pane, Luigi, Campana, Raffaella, Repetto, Barbara, Mariottini, Gian Luigi, Pruzzo, Carla. Detection of free‐living and plankton‐bound vibrios in coastal waters of the Adriatic Sea (Italy) and study of their pathogenicity‐associated properties. Environmental microbiology, vol.8, no.7, 1299-1305.

  2. Feldhusen, Frerk. The role of seafood in bacterialfoodborne diseases. Microbes and infection, vol.2, no.13, 1651-1660.

  3. Oliver, J D, Warner, R A, Cleland, D R. Distribution and ecology of Vibrio vulnificus and other lactose-fermenting marine vibrios in coastal waters of the southeastern United States. Applied and environmental microbiology, vol.44, no.6, 1404-1414.

  4. Israel Vibrio Study Group. Lancet Bisharat N 1421 354 1999 Clinical, epidemiological, and microbiological features of Vibrio vulnificus biogroup 3 causing outbreaks of wound infection and bacteraemia in Israel BisharatNAgmonVFinkelsteinRRazRBen-DrorGLernerLSobohSColodnerRCameronDNWykstraDLSwerdlowDLFarmerJJIII. 1999. Clinical, epidemiological, and microbiological features of Vibrio vulnificus biogroup 3 causing outbreaks of wound infection and bacteraemia in Israel. Israel Vibrio Study Group. Lancet 354:1421-1424. 

  5. Strom, Mark S., Paranjpye, Rohinee N.. Epidemiology and pathogenesis of Vibrio vulnificus. Microbes and infection, vol.2, no.2, 177-188.

  6. Blake, Paul A., Merson, Michael H., Weaver, Robert E., Hollis, Dannie G., Heublein, Peter C.. Disease Caused by a Marine Vibrio : Clinical Characteristics and Epidemiology. The New England journal of medicine, vol.300, no.1, 1-5.

  7. Hlady, W G, Klontz, K C. The epidemiology of Vibrio infections in Florida, 1981-1993.. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.173, no.5, 1176-1183.

  8. Jones, Melissa K., Oliver, James D.. Vibrio vulnificus: Disease and Pathogenesis. Infection and immunity, vol.77, no.5, 1723-1733.

  9. Böer, Simone I., Heinemeyer, Ernst-August, Luden, Katrin, Erler, René, Gerdts, Gunnar, Janssen, Frank, Brennholt, Nicole. Temporal and Spatial Distribution Patterns of Potentially Pathogenic Vibrio spp. at Recreational Beaches of the German North Sea. Microbial ecology, vol.65, no.4, 1052-1067.

  10. Jones, Erin H., Feldman, Katherine A., Palmer, Amanda, Butlera, Erin, Blythe, David, Mitchell, Clifford S.. Vibrio Infections and Surveillance in Maryland, 2002-2008. Public health reports : PHR, vol.128, no.6, 537-545.

  11. J. Microbiol. Gulig PA 118 43 2005 Molecular pathogenesis of Vibrio vulnificus GuligPABourdageKLStarksAM. 2005. Molecular pathogenesis of Vibrio vulnificus. J. Microbiol. 43(Suppl 1):118-131. 

  12. Satchell, Karla J. Fullner. MARTX, Multifunctional Autoprocessing Repeats-in-Toxin Toxins. Infection and immunity, vol.75, no.11, 5079-5084.

  13. Shen, Aimee. Autoproteolytic Activation of Bacterial Toxins. Toxins, vol.2, no.5, 963-977.

  14. Satchell, Karla J.F.. Structure and Function of MARTX Toxins and Other Large Repetitive RTX Proteins. Annual review of microbiology, vol.65, 71-90.

  15. Roig, Francisco J., González-Candelas, Fernando, Amaro, Carmen. Domain Organization and Evolution of Multifunctional Autoprocessing Repeats-in-Toxin (MARTX) Toxin in Vibrio vulnificus. Applied and environmental microbiology, vol.77, no.2, 657-668.

  16. Chung, K.-J., Cho, E.-J., Kim, M.K., Kim, Y.R., Kim, S.-H., Yang, H.-Y., Chung, K.-C., Lee, S.E., Rhee, J.H., Choy, H.E.. RtxA1-Induced Expression of the Small GTPase Rac2 Plays a Key Role in the Pathogenicity of Vibrio vulnificus. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.201, no.1, 97-105.

  17. Jeong, Hee-Gon, Satchell, Karla J. F.. Additive Function of Vibrio vulnificus MARTX Vv and VvhA Cytolysins Promotes Rapid Growth and Epithelial Tissue Necrosis During Intestinal Infection. PLoS pathogens, vol.8, no.3, e1002581-.

  18. Kim, Young Ran, Lee, Shee Eun, Kook, Hyun, Yeom, Jung A., Na, Hee Sam, Kim, Soo Young, Chung, Sun Sik, Choy, Hyon E., Rhee, Joon Haeng. Vibrio vulnificus RTX toxin kills host cells only after contact of the bacteria with host cells. Cellular microbiology, vol.10, no.4, 848-862.

  19. Lee, B.C., Choi, S.H., Kim, T.S.. Vibrio vulnificus RTX toxin plays an important role in the apoptotic death of human intestinal epithelial cells exposed to Vibrio vulnificus. Microbes and infection, vol.10, no.14, 1504-1513.

  20. J. Microbiol. Lee JH 146 45 2007 Identification and characterization of the Vibrio vulnificus rtxA essential for cytotoxicity in vitro and virulence in mice LeeJHKimMWKimBSKimSMLeeBCKimTSChoiSH. 2007. Identification and characterization of the Vibrio vulnificus rtxA essential for cytotoxicity in vitro and virulence in mice. J. Microbiol. 45:146-152. 

  21. Lo, Horng-Ren, Lin, Jen-Hsing, Chen, Yi-Hsuan, Chen, Chun-Liang, Shao, Chung-Ping, Lai, Yi-Chi, Hor, Lien-I. RTX Toxin Enhances the Survival of Vibrio vulnificus During Infection by Protecting the Organism From Phagocytosis. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.203, no.12, 1866-1874.

  22. Lee, Chung‐Te, Pajuelo, David, Llorens, Amparo, Chen, Yi‐Hsuan, Leiro, José M., Padrós, Francesc, Hor, Lien‐I, Amaro, Carmen. MARTX of Vibrio vulnificus biotype 2 is a virulence and survival factor. Environmental microbiology, vol.15, no.2, 419-432.

  23. Lee, T.H., Kim, M.H., Lee, C.S., Lee, J.H., Rhee, J.H., Chung, K.M.. Protection against Vibrio vulnificus infection by active and passive immunization with the C-terminal region of the RtxA1/MARTXVv protein. Vaccine, vol.32, no.2, 271-276.

  24. Lee, Tae Hee, Kim, Young Ran, Rhee, Joon Haeng, Kim, Jin-Hong, Woo, Hye Ryun, Chung, Kyung Min. Characterization of monoclonal antibodies targeting the RtxA1 toxin of Vibrio vulnificus. Process biochemistry, vol.46, no.7, 1500-1508.

  25. Lee, Shee Eun, Kim, Soo Young, Kim, Choon Mee, Kim, Mi-Kwang, Kim, Young Ran, Jeong, Kwangjoon, Ryu, Hwa-Ja, Lee, Youn Suhk, Chung, Sun Sik, Choy, Hyon E., Rhee, Joon Haeng. The pyrH Gene of Vibrio vulnificus Is an Essential In Vivo Survival Factor. Infection and immunity, vol.75, no.6, 2795-2801.

  26. Secher, Thomas, Fas, Stefanie, Fauconnier, Louis, Mathieu, Marieke, Rutschi, Oliver, Ryffel, Bernhard, Rudolf, Michael. The Anti- Pseudomonas aeruginosa Antibody Panobacumab Is Efficacious on Acute Pneumonia in Neutropenic Mice and Has Additive Effects with Meropenem. PloS one, vol.8, no.9, e73396-.

  27. DiRita, V. J., Starks, Angela M., Schoeb, Trenton R., Tamplin, Mark L., Parveen, Salina, Doyle, Thomas J., Bomeisl, Philip E., Escudero, Gloria M., Gulig, Paul A.. Pathogenesis of Infection by Clinical and Environmental Strains of Vibrio vulnificus in Iron-Dextran-Treated Mice. Infection and immunity, vol.68, no.10, 5785-5793.

  28. Poole, M D, Oliver, J D. Experimental pathogenicity and mortality in ligated ileal loop studies of the newly reported halophilic lactose-positive Vibrio sp. Infection and immunity, vol.20, no.1, 126-129.

  29. Brennt, C E, Wright, A C, Dutta, S K, Morris, J G. Growth of Vibrio vulnificus in serum from alcoholics: association with high transferrin iron saturation.. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.164, no.5, 1030-1032.

  30. Bullen, J J, Spalding, P B, Ward, C G, Gutteridge, J M. Hemochromatosis, iron and septicemia caused by Vibrio vulnificus.. Archives of internal medicine, vol.151, no.8, 1606-1609.

  31. Kraffert, Craig A., Hogan, Daniel J.. Vibrio vulnificus infection and iron overload. Journal of the American Academy of Dermatology, vol.26, no.1, 140-.

  32. Vollberg, C M, Herrera, J L. Vibrio vulnificus infection: an important cause of septicemia in patients with cirrhosis.. Southern medical journal, vol.90, no.10, 1040-1042.

  33. Hor, Lien‐I, Chang, Yir‐kun, Chang, Chien‐chung, Lei, Huan‐yao, Ou, Jonathan T.. Mechanism of High Susceptibility of Iron‐Overloaded Mouse to Vibrio vulnificus Infection. Microbiology and immunology, vol.44, no.11, 871-878.

  34. J. Fla. Med. Assoc. Hlady WG 536 80 1993 Vibrio vulnificus from raw oysters. Leading cause of reported deaths from foodborne illness in Florida HladyWGMullenRCHopkinRS. 1993. Vibrio vulnificus from raw oysters. Leading cause of reported deaths from foodborne illness in Florida. J. Fla. Med. Assoc. 80:536-538. 

  35. Jackson, J K, Murphree, R L, Tamplin, M L. Evidence that mortality from Vibrio vulnificus infection results from single strains among heterogeneous populations in shellfish. Journal of clinical microbiology, vol.35, no.8, 2098-2101.

  36. Medzhitov, Ruslan, Janeway Jr., Charles. Innate Immunity. The New England journal of medicine, vol.343, no.5, 338-344.

  37. Queen, Jessica, Satchell, Karla J. Fullner. Neutrophils Are Essential for Containment of Vibrio cholerae to the Intestine during the Proinflammatory Phase of Infection. Infection and immunity, vol.80, no.8, 2905-2913.

  38. Tsuchiya, Takahiro, Mitsuo, Eriko, Hayashi, Nahoko, Hikita, Yuuko, Nakao, Hiroshi, Yamamoto, Shigeo, Miyamoto, Katsushiro, Tsujibo, Hiroshi. Vibrio vulnificus Damages Macrophages during the Early Phase of Infection. Infection and immunity, vol.75, no.9, 4592-4596.

  39. Bishop, Anne L., Patimalla, Bharathi, Camilli, Andrew. Vibrio cholerae-Induced Inflammation in the Neonatal Mouse Cholera Model. Infection and immunity, vol.82, no.6, 2434-2447.

  40. Kim, Young Ran, Lee, Shee Eun, Kang, In-Chol, Nam, Kwang Il, Choy, Hyon E., Rhee, Joon Haeng. A Bacterial RTX Toxin Causes Programmed Necrotic Cell Death Through Calcium-Mediated Mitochondrial Dysfunction. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.207, no.9, 1406-1415.

  41. Kwak, Jayme S., Jeong, Hee-Gon, Satchell, Karla J. F.. Vibrio vulnificus rtxA1 gene recombination generates toxin variants with altered potency during intestinal infection. Proceedings of the National Academy of Sciences of the United States of America, vol.108, no.4, 1645-1650.

  42. Klontz, Karl C.. Syndromes ofVibrio vulnificusInfections : Clinical and Epidemiologic Features in Florida Cases, 1981-1987. Annals of internal medicine, vol.109, no.4, 318-.

  43. Chen, Y.-C., Chang, C.-C., Chang, S.-Y., Su, J.-H.. A recombinant metalloprotease antigen of Vibrio vulnificus elicits protective antibodies in a murine model. Letters in applied microbiology, vol.50, no.2, 168-172.

  44. Devi, S J, Hayat, U, Frasch, C E, Kreger, A S, Morris Jr, J G. Capsular polysaccharide-protein conjugate vaccines of carbotype 1 Vibrio vulnificus: construction, immunogenicity, and protective efficacy in a murine model. Infection and immunity, vol.63, no.8, 2906-2911.

  45. Devi, S J, Hayat, U, Powell, J L, Morris Jr, J G. Preclinical immunoprophylactic and immunotherapeutic efficacy of antisera to capsular polysaccharide-tetanus toxoid conjugate vaccines of Vibrio vulnificus. Infection and immunity, vol.64, no.6, 2220-2224.

  46. Kreger, A S, Gray, L D, Testa, J. Protection of mice against Vibrio vulnificus disease by vaccination with surface antigen preparations and anti-surface antigen antisera. Infection and immunity, vol.45, no.3, 537-543.

  47. Hor, L I, Chang, T T, Wang, S T. Survival of Vibrio vulnificus in whole blood from patients with chronic liver diseases: association with phagocytosis by neutrophils and serum ferritin levels.. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.179, no.1, 275-278.

  48. Weingart, Christine L., Mobberley-Schuman, Paula S., Hewlett, Erik L., Gray, Mary C., Weiss, Alison A.. Neutralizing Antibodies to Adenylate Cyclase Toxin Promote Phagocytosis ofBordetella pertussisby Human Neutrophils. Infection and immunity, vol.68, no.12, 7152-7155.

  49. Abboud, Nareen, Chow, Siu-Kei, Saylor, Carolyn, Janda, Alena, Ravetch, Jeffery V., Scharff, Matthew D., Casadevall, Arturo. A requirement for FcγR in antibody-mediated bacterial toxin neutralization. The Journal of experimental medicine, vol.207, no.11, 2395-2405.

  50. Kashimoto, Takashige, Ueno, Shunji, Hanajima, Miyuki, Hayashi, Hisae, Akeda, Yukihiro, Miyoshi, Shinichi, Hongo, Toshiharu, Honda, Takeshi, Susa, Nobuyuki. Vibrio vulnificus Induces Macrophage Apoptosis In Vitro and In Vivo. Infection and immunity, vol.71, no.1, 533-535.

  51. Frey, J.. The role of RTX toxins in host specificity of animal pathogenic Pasteurellaceae. Veterinary microbiology, vol.153, no.1, 51-58.

  52. Martín, César, Uribe, Kepa B., Gómez-Bilbao, Geraxane, Ostolaza, Helena. Adenylate Cyclase Toxin Promotes Internalisation of Integrins and Raft Components and Decreases Macrophage Adhesion Capacity. PloS one, vol.6, no.2, e17383-.

  53. Sun, Yude, Clinkenbeard, Kenneth D, Clarke, Cyril, Cudd, Laura, Highlander, Sarah K, Dabo, S.Mady. Pasteurella haemolytica leukotoxin induced apoptosis of bovine lymphocytes involves DNA fragmentation. Veterinary microbiology, vol.65, no.2, 153-166.

  54. Thumbikat, Praveen, Dileepan, Thamotharampillai, Kannan, Mathur S., Maheswaran, Samuel K.. Mechanisms underlying Mannheimia haemolytica leukotoxin-induced oncosis and apoptosis of bovine alveolar macrophages. Microbial pathogenesis, vol.38, no.4, 161-172.

  55. Dileepan, T., Kachlany, S. C., Balashova, N. V., Patel, J., Maheswaran, S. K.. Human CD18 Is the Functional Receptor forAggregatibacter actinomycetemcomitansLeukotoxin. Infection and immunity, vol.75, no.10, 4851-4856.

  56. Lally, Edward T., Hill, R.Blake, Kieba, Irene R., Korostoff, Jon. The interaction between RTX toxins and target cells. Trends in microbiology, vol.7, no.9, 356-361.

  57. Lally, Edward T., Kieba, Irene R., Sato, Atsushi, Green, Cecelia L., Rosenbloom, Joel, Korostoff, Jon, Wang, Jian Fei, Shenker, Bruce J., Ortlepp, Susan, Robinson, Martyn K., Billings, Paul C.. RTX Toxins Recognize a β2 Integrin on the Surface of Human Target Cells. The Journal of biological chemistry, vol.272, no.48, 30463-30469.

  58. Morova, Jana, Osicka, Radim, Masin, Jiri, Sebo, Peter. RTX cytotoxins recognize β 2 integrin receptors through N-linked oligosaccharides. Proceedings of the National Academy of Sciences of the United States of America, vol.105, no.14, 5355-5360.

  59. 10.1093/infdis/168.3.758 

  60. Moore, R. N., Wright, Anita C., Powell, Jan L., Tanner, Mike K., Ensor, Lynne A., Karpas, Arthur B., Morris Jr., J. Glenn, Sztein, Marcelo B.. Differential Expression of Vibrio vulnificus Capsular Polysaccharide. Infection and immunity, vol.67, no.5, 2250-2257.

  61. Chung, Kyung Min, Nybakken, Grant E., Thompson, Bruce S., Engle, Michael J., Marri, Anantha, Fremont, Daved H., Diamond, Michael S.. Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc γ Receptor-Dependent and -Independent Mechanisms. Journal of virology, vol.80, no.3, 1340-1351.

LOADING...

관련 콘텐츠

오픈액세스(OA) 유형

BRONZE

출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문

이 논문과 함께 이용한 콘텐츠

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로