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Drug metabolism and disposition: the biological fate of chemicals, v.43 no.7, 2015년, pp.1100 - 1107
Lo, Sheng-Nan , Shen, Chien-Chang , Chang, Chia-Yu , Tsai, Keng-Chang , Huang, Chiung-Chiao , Wu, Tian-Shung , Ueng, Yune-Fang
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The protoberberine alkaloid berberine carries methylenedioxy moiety and exerts a variety of pharmacological effects, such as anti-inflammation and lipid-lowering effects. Berberine causes potent CYP1B1 inhibition, whereas CYP1A2 shows resistance to the inhibition. To reveal the influence of oxidativ...
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