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[해외논문] Protective Effect of the Fruit Hull of Gleditsia sinensis on LPS-Induced Acute Lung Injury Is Associated with Nrf2 Activation 원문보기

Evidence-based Complementary and Alternative Medicine : eCAM, v.2012, 2012년, pp.974713 -   

Choi, Jun-Young (Department of Korean Medical Science, Korean Medicine Hospital, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) ,  Kwun, Min Jung (Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) ,  Kim, Kyun Ha (Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) ,  Lyu, Ji Hyo (Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) ,  Han, Chang Woo (Department of Internal Medicine, Korean Medicine Hospital, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) ,  Jeong, Han-Sol (Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) ,  Ha, Ki-Tae (Division of Applied Medicine, School of Korean Medicine, Pusan National University, Yangsan 626-870, Republic of Korea) ,  Jung, Hee-Jae (Division of Allergy, Immune and Respiratory System, Department of Internal Medicine, Colle) ,  Lee, Beom-Joon ,  Sadikot, Ruxana T. ,  Christman, John W. ,  Jung, Sung-Ki ,  Joo, Myungsoo

Abstract ▼ AI-Helper 아이콘AI-Helper

The fruit hull of Gleditsia sinensis (FGS) has been prescribed as a traditional eastern Asian medicinal remedy for the treatment of various respiratory diseases, but the efficacy and underlying mechanisms remain poorly characterized. Here, we explored a potential usage of FGS for the treatment of ac...

참고문헌 (37)

  1. 1 Luh SP Chiang CH Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies Journal of Zhejiang University 2007 8 1 60 69 17173364 

  2. 2 Notter RH Finkelstein JN Holm BA Lung Injury: Mechanisms, Pathophysiology, and Therapy 2005 Boca Raton, Fla, USA Taylor & Francis 

  3. 3 Matuschak GM Lechner AJ Acute lung injury and the acute respiratory distress syndrome: pathophysiology and treatment Missouri medicine 2010 107 4 252 258 20806836 

    상세보기

  4. 4 Knaus WA Sun X Hakim RB Wagner DP Evaluation of definitions for adult respiratory distress syndrome American Journal of Respiratory and Critical Care Medicine 1994 150 2 311 317 8049808 

    상세보기

  5. 5 Martich GD Danner RL Ceska M Suffredini AF Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents Journal of Experimental Medicine 1991 173 4 1021 1024 2007851 

    상세보기

  6. 6 Miller EJ Cohen AB Nagao S Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality American Review of Respiratory Disease 1992 146 2 427 432 1489135 

    상세보기

  7. 7 Beutler B Rietschel ET Innate immune sensing and its roots: the story of endotoxin Nature Reviews Immunology 2003 3 2 169 176 

  8. 8 Rossaint R Gerlach H Schmidt-Ruhnke H Efficacy of inhaled nitric oxide in patients with severe ARDS Chest 1995 107 4 1107 1115 7705124 

    상세보기

  9. 9 Meduri GU Belenchia JM Estes RJ Wunderink RG El Torky M Leeper KV Fibroproliferative phase of ARDS; Clinical findings and effects of corticosteroids Chest 1991 100 4 943 952 1914609 

    상세보기

  10. 10 de Lange DW Meulenbelt J Do corticosteroids have a role in preventing or reducing acute toxic lung injury caused by inhalation of chemical agents? Clinical Toxicology 2011 49 2 61 71 21370942 

    상세보기

  11. 11 Petrucci N Iacovelli W Lung protective ventilation strategy for the acute respiratory distress syndrome Cochrane Database of Systematic Reviews 2007 3 Article ID CD003844. 

  12. 12 Kuang L Zhang K Chinese Pharmacopoeial Commission Pharmacopoeia of the People's Republic of China 2005 1 Beijing, China People's Medical Publishing House 96 97 

  13. 13 Chan K Kan YW Nrf2 is essential for protection against acute pulmonary injury in mice Proceedings of the National Academy of Sciences of the United States of America 1999 96 22 12731 12736 10535991 

    상세보기

  14. 14 Joo M Kwon M Sadikot RT Induction and function of lipocalin prostaglandin D synthase in host immunity Journal of Immunology 2007 179 4 2565 2575 

    상세보기

  15. 15 Schwartz MD Moore EE Moore FA Nuclear factor- κ B is activated in alveolar macrophages from patients with acute respiratory distress syndrome Critical Care Medicine 1996 24 8 1285 1292 8706481 

  16. 16 Xie QW Kashiwabara Y Nathan C Role of transcription factor NF- κ B/Rel in induction of nitric oxide synthase The Journal of Biological Chemistry 1994 269 7 4705 4708 7508926 

  17. 17 Rangasamy T Guo J Mitzner WA Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice Journal of Experimental Medicine 2005 202 1 47 59 15998787 

    상세보기

  18. 18 Thimmulappa RK Lee H Rangasamy T Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis Journal of Clinical Investigation 2006 116 4 984 995 16585964 

    상세보기

  19. 19 Johnson JA Johnson DA Kraft AD The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration Annals of the New York Academy of Sciences 2008 1147 61 69 19076431 

    상세보기

  20. 20 Bensky D Clavey S Stöger E Chinese Herbal Medicine: Materia Medica 2004 Seattle, Wash, USA Eastland Press 

  21. 21 Zhang Z Synopsis of Prescriptions of the Golden Chamber (Jinkui Yaolue Fanglun) 1987 Beijing, China New World Press 

  22. 22 Fu LJ Dai Y Wang ZT Zhang M Inhibition of experimental allergic rhinitis by the n-butanol fraction from the anomalous fruits of Gleditsia sinensis Biological and Pharmaceutical Bulletin 2003 26 7 974 977 12843621 

    상세보기

  23. 23 Okada Y Takahashi K Okuyama T Shibata S Gleditsia saponins. II. Locations of monoterpenyl moieties in the molecule of Gleditsia saponin C (GS-C) Planta Medica 1982 46 2 74 77 17396946 

  24. 24 Zhang Z Koike K Jia Z Nikaido T Guo D Zheng J Triterpenoidal saponins from Gleditsia sinensis Phytochemistry 1999 52 4 715 722 10570830 

    상세보기

  25. 25 Zhang Z Koike K Jia Z Nikaido T Guo D Zheng J Triterpenoidal saponins acylated with two monoterpenic acids from Gleditsia sinensis Chemical and Pharmaceutical Bulletin 1999 47 3 388 393 10212388 

    상세보기

  26. 26 Li D Xu Z-M Meng J-F Tong S-J Guo W-F Antisepsis of Natural Compositions in Gleditsia sinensis Journal of Nanjing University of Traditional Chinese Medicine 2011 27 89 91 

  27. 27 Peng Q Xu R Yin N Jiang J-X Zhu L-W Study on antibacterial activity of Saponins from Gleditsia sinensis and Camellia Chemistry and Industty of Forest Products 2009 29 203 206 

  28. 28 Chen F Castranova V Shi X Demers LM New insights into the role of nuclear factor- κ B, a ubiquitous transcription factor in the initiation of diseases Clinical Chemistry 1999 45 1 7 17 9895331 

  29. 29 Imanifooladi AA Yazdani S Nourani MR The role of nuclear factor- κ B in inflammatory lung disease Inflammation and Allergy—Drug Targets 2010 9 3 197 205 20687892 

  30. 30 Wright JG Christman JW The role of nuclear factor Kappa B in the pathogenesis of pulmonary diseases: implications for therapy American Journal of Respiratory Medicine 2003 2 3 211 219 14720003 

    상세보기

  31. 31 Mochizuki M Ishii Y Itoh K Role of 15-deoxyΔ prostaglandin J2 and Nrf2 pathways in protection against acute lung injury American Journal of Respiratory and Critical Care Medicine 2005 171 11 1260 1266 15750045 

  32. 32 Rangasamy T Cho CY Thimmulappa RK Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice Journal of Clinical Investigation 2004 114 9 1248 1259 15520857 

    상세보기

  33. 33 Cho HY Reddy SP Kleeberger SR Nrf2 defends the lung from oxidative stress Antioxidants and Redox Signaling 2006 8 1-2 76 87 16487040 

  34. 34 Itoh K Chiba T Takahashi S An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements Biochemical and Biophysical Research Communications 1997 236 2 313 322 9240432 

    상세보기

  35. 35 Lyu JH Lee GS Kim KH Ent-kaur-16-en-19-oic acid, isolated from the roots of Aralia continentalis, induces activation of Nrf2 Journal of Ethnopharmacology 2011 137 3 1442 1449 21884778 

    상세보기

  36. 36 Reuter S Gupta SC Chaturvedi MM Aggarwal BB Oxidative stress, inflammation, and cancer: how are they linked? Free Radical Biology and Medicine 2010 49 11 1603 1616 20840865 

    상세보기

  37. 37 Kaspar JW Niture SK Jaiswal AK Nrf2:INrf2 (Keap1) signaling in oxidative stress Free Radical Biology and Medicine 2009 47 9 1304 1309 19666107 

    상세보기
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