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Whole cell bioconversion of vitamin D3 to calcitriol using Pseudonocardia sp. KCTC 1029BP

Bioprocess and biosystems engineering, v.38 no.7, 2015년, pp.1281 - 1290  

Kang, Dae-Jung ,  Im, Jong-Hyuk ,  Kang, Jae-Hoon ,  Kim, Kyoung Heon

Abstract AI-Helper 아이콘AI-Helper

Calcitriol is an important drug used for treating osteoporosis, which can be produced from vitamin D-3. The current method of producing calcitriol from vitamin D-3 during cultivation of microbial cells results in low yields of calcitriol and high purification costs. Therefore, in this study, the ste...

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