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An ethanol root extract of Cynanchum wilfordii containing acetophenones suppresses the expression of VCAM-1 and ICAM-1 in TNF-α-stimulated human aortic smooth muscle cells through the NF-κB pathway 원문보기

International journal of molecular medicine, v.35 no.4, 2015년, pp.915 - 924  

KOO, HYUN JUNG (Department of Medicinal and Industrial Crops, Korea National College of Agriculture and Fisheries, Jeonju 560-500, Republic of Korea) ,  SOHN, EUN-HWA (Department of Herbal Medicine Resources, Kangwon National University, Samcheok, Gangwon-do 245-710, Republic of Korea) ,  PYO, SUHKNEUNG (Division of Immunopharmacology, School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 440-746, Republic of Korea) ,  WOO, HAN GOO (Department of Life Science, Gachon University, Seongnam, Gyeonggi-Do 461-701, Republic of Korea) ,  PARK, DAE WON (Department of Life Science, Gachon University, Seongnam, Gyeonggi-Do 461-701, Republic of Korea) ,  HAM, YOUNG-MIN (Jeju Biodiversity Research Institute, Jeju Technopark, Jeju 699-943, Republic of Korea) ,  JANG, SEON-A (Department of Life Science, Gachon University, Seongnam, Gyeonggi-Do 461-701, Republic of Korea) ,  PARK, SOO-YEONG (Jeju Biodiversity Research Institute, Jeju Technopark, Jeju 699-943, Republic of Korea) ,  KANG, SE CHAN (Department of Life Science, Gachon University, Seongnam, Gyeonggi-Do 461-701, Republic of Korea)

Abstract AI-Helper 아이콘AI-Helper

The root of Cynanchum wilfordii (C. wilfordii) contains several biologically active compounds which have been used as traditional medicines in Asia. In the present study, we evaluated the anti-inflammatory effects of an ethanol root extract of C. wilfordii (CWE) on tumor necrosis factor (TNF)-&alpha...

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