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International journal of biological sciences, v.11 no.4, 2015년, pp.472 - 481
Li, Ming (1. Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka, Japan.) , Guo, Kequan (2. Department of Cardiac Surgery, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China.) , Vanella, Luca (3. Department of Drug Science, Section of Biochemistry, University of Catania, Catania, Italy.) , Taketani, Shigeru (4. Department of Biotechnology, Kyoto Institute of Technology, Kyoto, Japan.) , Adachi, Yasushi (5. Division of Surgical Pathology, Toyooka Hospital, Hyogo, Japan.) , Ikehara, Susumu (1. Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka, Japan.)
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Nonalcoholic fatty liver disease (NAFLD) is associated with insulin resistance, oxidative stress, and obesity. The db/db mouse model displays increased levels of insulin resistance, obesity, and an over-accumulation of hepatic triglycerides, making it an excellent model for studying NAFLD. In db/db ...
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