참고문헌 (178)

1. Genetic loci associated with circulating levels of very long - chain saturated fatty acids Lemaitre 2015 Lipid Res 

2. Mechanisms by which permeabilise mitochondria during apoptosis Dewson 122 Cell Sci 2009 

3. Visualization of ceramide channels by transmission electron microscopy Samanta 1808 Biochim Biophys Acta 2011 

4. wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment Kirin 3174 Genome Hum Mol Genet 22 2013 10.1093/hmg/ddt169 

   상세보기

5. The complexity of sphingolipid biosynthesis in the endoplasmic reticulum Tidhar 2511 Biochim Biophys Acta 2013 10.1016/j.bbamcr.2013.04.010 

   상세보기

6. The lipids ceramide form large stable channels Implications for apoptosis Siskind 275 Biol Chem 16 2000 

7. Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth Hartmann 620 Int J Biochem Cell Biol 2012 10.1016/j.biocel.2011.12.019 

   상세보기

8. Epidermal surface lipids Dermatoendocrinol Pappas 1 2009 

9. topology of ceramide synthase in yeast Kageyama 398 Biochem J 2006 

10. a Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent - resistant membranes Park 525 Hepatology 2013 10.1002/hep.26015 

    상세보기

11. Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels Ben 286 Biol Chem 2011 

12. Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma attenuation of ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis Karahatay 256 Cancer Lett 18 2007 

13. deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation 1002063 Zhao PLoS Genet 2011 

    

14. synthases and ceramide levels are increased in breast cancer tissue Schiffmann 745 Carcinogenesis 30 2009 10.1093/carcin/bgp061 

    상세보기

15. synthases reexamining longevity Park 215 Exp Pharmacol 2013 

16. a Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent - resistant membranes Park 525 Hepatology 2013 10.1002/hep.26015 

    상세보기

17. and cell death outer membrane permeabilization and beyond Tait 621 Mitochondria Nat Rev Mol Cell Biol 11 2010 10.1038/nrm2952 

    상세보기

18. der von Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis : a link to ceramide synthase - Rabionet 283 Biol Chem 2008 

19. Two mammalian longevity assurance gene LAG family members trh trh regulate dihydroceramide synthesis using different fatty acyl - CoA donors Riebeling 1 Biol Chem 2003 

20. Cholera toxin binds to lipid rafts but has a limited specificity for ganglioside Blank 1 Cell Biol 2007 

21. Stress - induced ER to Golgi translocation of ceramide synthase is dependent on proteasomal processing Sridevi 1 Cell Res 2010 

22. Gap junction inhibition prevents drug - induced liver toxicity and fulminant hepatic failure Patel 179 Nat Biotechnol 30 2012 10.1038/nbt.2089 

    상세보기

23. brittle hair impaired intelligence decreased fertility short stature syndrome Jorizzo 106 Dermatol 1982 

24. Regulation of ceramide biosynthesis by TOR complex Aronova 148 Cell Metab 2008 10.1016/j.cmet.2007.11.015 

    상세보기

25. Mutation for nonsyndromic mental retardation in the trans enoyl - CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability leading to change in sphingolipid profile Abe 288 Biol Chem 2013 

26. synthase modulates TRAIL sensitivity and nuclear translocation of active caspase - in colon cancer cells White 1132 Oncogene 28 2009 10.1038/onc.2008.468 

    상세보기

27. The crystal structure of human CD with and without alpha - galactosylceramide Koch 1 Nat Immunol 2005 

28. Sphingoid long chain bases prevent lung infection byPseudomonas aeruginosa Pewzner 1205 Mol Med 2014 

29. Cholera toxin binds to lipid rafts but has a limited specificity for ganglioside Blank 1 Cell Biol 2007 

30. synthase modulates TRAIL sensitivity and nuclear translocation of active caspase - in colon cancer cells White 1132 Oncogene 28 2009 10.1038/onc.2008.468 

    상세보기

31. Differential expression of dihydro ceramide synthases in mouse oligodendrocyte - specific expression of Becker 129 brain Cell Biol 2008 

32. Circulating sphingolipid biomarkers in models of type diabetes Fox 1 Lipid Res 2011 

33. Upstream of growth and differentiation factor uog a mammalian homolog of the yeast longevity assurance gene LAG regulates stearoyl - sphinganine dihydro ceramide synthesis in a fumonisin independent manner in mammalian cells Venkataraman 1 Biol Chem 18 2002 

34. critical role for ceramide synthase in liver homeostasis alterations in lipid metabolic pathways Pewzner 285 Biol Chem 2010 

35. synthases roles in cell signaling Stiban 688 physiology Adv Exp Med Biol 2010 

36. synthases confer distinct roles in radiation - induced apoptosis in HeLa cells Mesicek 1300 Cell Signal 22 2010 10.1016/j.cellsig.2010.04.006 

    상세보기

37. - like role of regulatory iNKT cells in autoimmune disease and tumour Wilson 211 immunity Nat Rev Immunol 2003 10.1038/nri1028 

    상세보기

38. Stress - induced ER to Golgi translocation of ceramide synthase is dependent on proteasomal processing Sridevi 1 Cell Res 2010 

39. Design of a potent CD binding NKT cell ligand as a vaccine adjuvant Li 1 Proc Natl Acad Sci USA 2010 

40. Expression of glucosylceramide synthase converting ceramide to glucosylceramide confers adriamycin resistance in human breast cancer cells Liu 274 Biol Chem 1999 

41. Kunos Hepatic cannabinoid receptors mediate diet - induced insulin resistance by increasing de novo synthesis of long - chain ceramides Cinar 1 Hepatology 2014 

42. Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism Mullen 52 Lipid Res 2011 

43. Upstream of growth and differentiation factor uog a mammalian homolog of the yeast longevity assurance gene LAG regulates stearoyl - sphinganine dihydro ceramide synthesis in a fumonisin independent manner in mammalian cells Venkataraman 1 Biol Chem 18 2002 

44. Mammalian ceramide synthases Levy 347 IUBMB Life 2010 10.1002/iub.319 

    상세보기

45. - like role of regulatory iNKT cells in autoimmune disease and tumour Wilson 211 immunity Nat Rev Immunol 2003 10.1038/nri1028 

    상세보기

46. longevity assurance homologue is a mainly testis - specific dihydro ceramide synthase with relatively broad substrate specificity Mizutani 398 Biochem J 2006 

47. The protein BAK is required for long - chain ceramide generation during apoptosis Siskind 285 Biol Chem 2010 

48. synthases and ceramide levels are increased in breast cancer tissue Schiffmann 745 Carcinogenesis 30 2009 10.1093/carcin/bgp061 

    상세보기

49. Characterization of ceramide synthase tissue distribution substrate specificity and inhibition by sphingosine phosphate Laviad 1 Biol Chem 2008 

50. critical role for ceramide synthase in liver homeostasis alterations in lipid metabolic pathways Pewzner 285 Biol Chem 2010 

51. synthases roles in cell signaling Stiban 688 physiology Adv Exp Med Biol 2010 

52. suppresses tumor cell invasion and is associated with decreased activities in breast cancer Fan 2015 J Cell Biochem 

53. Blumenfeld Structure - guided design of an invariant natural killer T cell agonist for optimum protection from type diabetes in non - obese diabetic mice Tohn 1 Clin Exp Immunol 2011 

54. haploinsufficiency inhibits b - oxidation and confers susceptibility to diet - induced steatohepatitis and insulin resistance Raichur 687 Cell Metab 20 2014 10.1016/j.cmet.2014.09.015 

    상세보기

55. suppresses tumor cell invasion and is associated with decreased activities in breast cancer Fan 2015 J Cell Biochem 

56. longevity assurance homologue is a mainly testis - specific dihydro ceramide synthase with relatively broad substrate specificity Mizutani 398 Biochem J 2006 

57. Ceramide synthases expression and role of ceramide synthase in the lung : insight from human lung cells and mouse models One 862968 Petrache 2013 

    

58. - specific ceramide galactosyltransferase expression phenotypically rescues CGT - deficient mice and demonstrates that CGT activity does not limit brain galactosylceramide level Zoller 190 Glia 2005 10.1002/glia.20230 

    상세보기

59. new functional motif in Hox domain - containing ceramide synthases : identification of a novel region flanking the Hox and TLC domains essential for activity Mesika 282 Biol Chem 2007 

60. Myelination in the absence of galactocerebroside and sulfatide : normal structure with abnormal function and regional instability Coetzee 209 Cell 1996 10.1016/S0092-8674(00)80093-8 

    상세보기

61. synthases reexamining longevity Park 215 Exp Pharmacol 2013 

62. Design of a potent CD binding NKT cell ligand as a vaccine adjuvant Li 1 Proc Natl Acad Sci USA 2010 

63. Interferon decreases ceramides with long - chain fatty acids : possible involvement in atopic dermatitis and psoriasis Tawada 134 Invest Dermatol 2014 

64. a Ceramide synthases as potential targets for therapeutic intervention in human diseases Park 671 Biochim Biophys Acta 2014 10.1016/j.bbalip.2013.08.019 

    상세보기

65. Reduced ceramide synthase activity causes progressive myoclonic epilepsy Mosbech 1 Ann Clin 2014 

66. Vom synthase deficiency in mice causes lipid alterations in sebum and results in alopecia Ebel 461 Biochem J 2014 

67. Increased ceramide synthase mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression Erez 391 Biochem Biophys Res Commun 2010 

68. Myelination in the absence of galactocerebroside and sulfatide : normal structure with abnormal function and regional instability Coetzee 209 Cell 1996 10.1016/S0092-8674(00)80093-8 

    상세보기

69. phosphate an enigmatic signalling lipid Spiegel 1 Nat Rev Mol Cell Biol 2003 

70. Decreased level of ceramides in stratum corneum of atopic dermatitis : an etiologic factor in atopic dry skin Imokawa 523 Invest Dermatol 1991 10.1111/1523-1747.ep12470233 

    상세보기

71. Regulation of ceramide synthase in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent Eberle 326 Biochem Pharmacol 2014 10.1016/j.bcp.2014.08.016 

    상세보기

72. enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of ATPase proton pump Fan 1682 Oncogene 2013 10.1038/onc.2012.183 

    상세보기

73. Protection of a ceramide synthase null mouse from drug - induced liver injury : role of gap junction dysfunction and connexin mislocalization Park 288 Biol Chem 2013 

74. - specific ceramide galactosyltransferase expression phenotypically rescues CGT - deficient mice and demonstrates that CGT activity does not limit brain galactosylceramide level Zoller 190 Glia 2005 10.1002/glia.20230 

    상세보기

75. vom Ablation of neuronal ceramide synthase in mice decreases ganglioside levels and expression of myelin - associated glycoprotein in oligodendrocytes Ginkel 1 Biol Chem 2012 

76. Protection of a ceramide synthase null mouse from drug - induced liver injury : role of gap junction dysfunction and connexin mislocalization Park 288 Biol Chem 2013 

77. Regulation of ceramide synthase in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent Eberle 326 Biochem Pharmacol 2014 10.1016/j.bcp.2014.08.016 

    상세보기

78. Testing the NKT cell hypothesis of human IDDM pathogenesis Lee 110 Clin Invest 2002 

79. Role of human longevity assurance gene ceramide in chemotherapy - induced cell death in human head and neck squamous cell carcinomas Senkal 1 Mol Cancer Ther 18 2007 

80. shift in sphingolipid composition from to increases susceptibility to apoptosis in HeLa cells Sassa 1031 Biochim Biophys Acta 24 2012 10.1016/j.bbalip.2012.04.008 

    상세보기

81. der Loss of ceramide synthase causes lethal skin barrier disruption Jennemann 586 Hum Mol Genet 21 2012 10.1093/hmg/ddr494 

    상세보기

82. Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous ceramide without requiring down - regulation of cellular FLICE inhibitory protein Voelkel 1320 Mol Cancer Ther 2005 10.1158/1535-7163.MCT-05-0086 

    상세보기

83. Altering the sphingolipid acyl chain composition prevents LPS mediated hepatic failure in mice by disrupting internalization Death Ali 1 Cell Dis 2013 

84. new functional motif in Hox domain - containing ceramide synthases : identification of a novel region flanking the Hox and TLC domains essential for activity Mesika 282 Biol Chem 2007 

85. is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl - CoA as acyl donor Lahiri 280 Biol Chem 2005 

86. Mammalian ceramide synthases Levy 347 IUBMB Life 2010 10.1002/iub.319 

    상세보기

87. Mitochondrial ceramide - rich macrodomains functionalize Bax upon irradiation One Lee 19783 2011 

88. Genetic loci associated with circulating levels of very long - chain saturated fatty acids Lemaitre 2015 Lipid Res 

89. and Adult ceramide synthase deficient mice exhibit myelin sheath defects cerebellar degeneration hepatocarcinomas Imgrund 284 Biol Chem 2009 

90. Necessary role for the Lag motif in dihydro ceramide synthase activity Spassieva 1 Biol Chem 2006 

91. Blumenfeld Structure - guided design of an invariant natural killer T cell agonist for optimum protection from type diabetes in non - obese diabetic mice Tohn 1 Clin Exp Immunol 2011 

92. a Ceramide synthases as potential targets for therapeutic intervention in human diseases Park 671 Biochim Biophys Acta 2014 10.1016/j.bbalip.2013.08.019 

    상세보기

93. The protein BAK is required for long - chain ceramide generation during apoptosis Siskind 285 Biol Chem 2010 

94. Expression of glucosylceramide synthase converting ceramide to glucosylceramide confers adriamycin resistance in human breast cancer cells Liu 274 Biol Chem 1999 

95. gene variant in is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND One 106631 Shiffman 2014 

    

96. Interferon decreases ceramides with long - chain fatty acids : possible involvement in atopic dermatitis and psoriasis Tawada 134 Invest Dermatol 2014 

97. Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels Ben 286 Biol Chem 2011 

98. Recognition of lyso - phospholipids by human natural killer T lymphocytes 1000228 Fox PLoS Biol 2009 

    

99. Regulation of ceramide biosynthesis by TOR complex Aronova 148 Cell Metab 2008 10.1016/j.cmet.2007.11.015 

    상세보기

100. Mammalian its related family members regulate synthesis of specific ceramides Mizutani 390 Biochem J 2005 

101. der Loss of ceramide synthase causes lethal skin barrier disruption Jennemann 586 Hum Mol Genet 21 2012 10.1093/hmg/ddr494 

     상세보기

102. Buren siRNA - mediated down - regulation of ceramide synthase leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy Separovic 2479 Anticancer Res 2012 

103. Mutations in cause autosomal recessive congenital ichthyosis in humans 1003536 Radner PLoS Genet 2013 

     

104. and cell death outer membrane permeabilization and beyond Tait 621 Mitochondria Nat Rev Mol Cell Biol 11 2010 10.1038/nrm2952 

     상세보기

105. Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth Hartmann 620 Int J Biochem Cell Biol 2012 10.1016/j.biocel.2011.12.019 

     상세보기

106. de and de Death receptor ligands in particular to overcome drug resistance Jong 20 Cancer Rev 2001 

107. der von Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis : a link to ceramide synthase - Rabionet 283 Biol Chem 2008 

108. Reduced ceramide synthase activity causes progressive myoclonic epilepsy Mosbech 1 Ann Clin 2014 

109. Gap junction inhibition prevents drug - induced liver toxicity and fulminant hepatic failure Patel 179 Nat Biotechnol 30 2012 10.1038/nbt.2089 

     상세보기

110. vom Ablation of neuronal ceramide synthase in mice decreases ganglioside levels and expression of myelin - associated glycoprotein in oligodendrocytes Ginkel 1 Biol Chem 2012 

111. Extreme Th bias of invariant cells in type diabetes Wilson 1 Nature 24 1998 

112. is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl - CoA as acyl donor Lahiri 280 Biol Chem 2005 

113. Regulation of ceramide synthase by casein kinase dependent phosphorylation inS cerevisiae Nov pii jbc ahead of print 621086 Fresques 114 Biol Chem 26 2014 

     

114. Differential expression of dihydro ceramide synthases in mouse oligodendrocyte - specific expression of Becker 129 brain Cell Biol 2008 

115. gene variant in is associated with rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND One 106631 Shiffman 2014 

     

116. Modulation of ceramide synthase activity via dimerization Laviad 287 Biol Chem 2012 

117. The lipids ceramide form large stable channels Implications for apoptosis Siskind 275 Biol Chem 16 2000 

118. Regulation of ceramide synthase by casein kinase dependent phosphorylation inS cerevisiae Nov pii jbc ahead of print 621086 Fresques 114 Biol Chem 26 2014 

     

119. Mitochondrial ceramide - rich macrodomains functionalize Bax upon irradiation One Lee 19783 2011 

120. haploinsufficiency inhibits b - oxidation and confers susceptibility to diet - induced steatohepatitis and insulin resistance Raichur 687 Cell Metab 20 2014 10.1016/j.cmet.2014.09.015 

     상세보기

121. Two mammalian longevity assurance gene LAG family members trh trh regulate dihydroceramide synthesis using different fatty acyl - CoA donors Riebeling 1 Biol Chem 2003 

122. synthase is regulated by proteasomal mediated turnover Sridevi 1 Biochim Biophys Acta 2009 

123. Mammalian its related family members regulate synthesis of specific ceramides Mizutani 390 Biochem J 2005 

124. deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation 1002063 Zhao PLoS Genet 2011 

     

125. Ablation of ceramide synthase causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain Zigdon 288 Biol Chem 2013 

126. Kunos Hepatic cannabinoid receptors mediate diet - induced insulin resistance by increasing de novo synthesis of long - chain ceramides Cinar 1 Hepatology 2014 

127. Recognition of lyso - phospholipids by human natural killer T lymphocytes 1000228 Fox PLoS Biol 2009 

     

128. Mutations in cause autosomal recessive congenital ichthyosis in humans 1003536 Radner PLoS Genet 2013 

     

129. type - specific expression pattern of ceramide synthase protein in mouse tissues Kremser 140 Cell Histochem Cell Biol 2013 

130. The crystal structure of human CD with and without alpha - galactosylceramide Koch 1 Nat Immunol 2005 

131. Visualization of ceramide channels by transmission electron microscopy Samanta 1808 Biochim Biophys Acta 2011 

132. topology of ceramide synthase in yeast Kageyama 398 Biochem J 2006 

133. Testing the NKT cell hypothesis of human IDDM pathogenesis Lee 110 Clin Invest 2002 

134. synthase mediates lipid - induced autophagy and hypertrophy in cardiomyocytes Russo 122 Clin Invest 2012 

135. shift in sphingolipid composition from to increases susceptibility to apoptosis in HeLa cells Sassa 1031 Biochim Biophys Acta 24 2012 10.1016/j.bbalip.2012.04.008 

     상세보기

136. Vom Inactivation of ceramide synthase in mice results in an altered sphingolipid metabolism and behavioral abnormalities Ebel 288 Biol Chem 2013 

137. type - specific expression pattern of ceramide synthase protein in mouse tissues Kremser 140 Cell Histochem Cell Biol 2013 

138. phosphate an enigmatic signalling lipid Spiegel 1 Nat Rev Mol Cell Biol 2003 

139. synthases confer distinct roles in radiation - induced apoptosis in HeLa cells Mesicek 1300 Cell Signal 22 2010 10.1016/j.cellsig.2010.04.006 

     상세보기

140. Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous ceramide without requiring down - regulation of cellular FLICE inhibitory protein Voelkel 1320 Mol Cancer Ther 2005 10.1158/1535-7163.MCT-05-0086 

     상세보기

141. brittle hair impaired intelligence decreased fertility short stature syndrome Jorizzo 106 Dermatol 1982 

142. - dependent protein kinase phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids 10.7554/eLife.03779 Muir 1 2014 

     상세보기

143. Epidermal surface lipids Dermatoendocrinol Pappas 1 2009 

144. a critical role for ceramide synthase in liver homeostasis II Insights into molecular changes leading to hepatopathy Pewzner 285 Biol Chem 2010 

145. is a ceramide synthase inhibitor in glioblastoma Jensen 111 Proc Natl Acad Sci USA 2014 

146. a critical role for ceramide synthase in liver homeostasis II Insights into molecular changes leading to hepatopathy Pewzner 285 Biol Chem 2010 

147. Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length Park 1754 Biochim Biophys Acta 2014 10.1016/j.bbalip.2014.09.009 

     상세보기

148. de and de Death receptor ligands in particular to overcome drug resistance Jong 20 Cancer Rev 2001 

149. Vom synthase deficiency in mice causes lipid alterations in sebum and results in alopecia Ebel 461 Biochem J 2014 

150. Modulation of ceramide synthase activity via dimerization Laviad 287 Biol Chem 2012 

151. synthase is regulated by proteasomal mediated turnover Sridevi 1 Biochim Biophys Acta 2009 

152. Circulating sphingolipid biomarkers in models of type diabetes Fox 1 Lipid Res 2011 

153. Role of human longevity assurance gene ceramide in chemotherapy - induced cell death in human head and neck squamous cell carcinomas Senkal 1 Mol Cancer Ther 18 2007 

154. Mutation for nonsyndromic mental retardation in the trans enoyl - CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability leading to change in sphingolipid profile Abe 288 Biol Chem 2013 

155. Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length Park 1754 Biochim Biophys Acta 2014 10.1016/j.bbalip.2014.09.009 

     상세보기

156. Ceramide synthases expression and role of ceramide synthase in the lung : insight from human lung cells and mouse models One 862968 Petrache 2013 

     

157. Vom Inactivation of ceramide synthase in mice results in an altered sphingolipid metabolism and behavioral abnormalities Ebel 288 Biol Chem 2013 

158. Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma attenuation of ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis Karahatay 256 Cancer Lett 18 2007 

159. Extreme Th bias of invariant cells in type diabetes Wilson 1 Nature 24 1998 

160. Mechanisms by which permeabilise mitochondria during apoptosis Dewson 122 Cell Sci 2009 

161. Necessary role for the Lag motif in dihydro ceramide synthase activity Spassieva 1 Biol Chem 2006 

162. Characterization of ceramide synthase tissue distribution substrate specificity and inhibition by sphingosine phosphate Laviad 1 Biol Chem 2008 

163. wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment Kirin 3174 Genome Hum Mol Genet 22 2013 10.1093/hmg/ddt169 

     상세보기

164. enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of ATPase proton pump Fan 1682 Oncogene 2013 10.1038/onc.2012.183 

     상세보기

165. - dependent protein kinase phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids 10.7554/eLife.03779 Muir 1 2014 

     상세보기

166. The complexity of sphingolipid biosynthesis in the endoplasmic reticulum Tidhar 2511 Biochim Biophys Acta 2013 10.1016/j.bbamcr.2013.04.010 

     상세보기

167. is a ceramide synthase inhibitor in glioblastoma Jensen 111 Proc Natl Acad Sci USA 2014 

168. The length of lipids bound to human CD molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation McCarthy 1 Exp Med 2007 

169. Altering the sphingolipid acyl chain composition prevents LPS mediated hepatic failure in mice by disrupting internalization Death Ali 1 Cell Dis 2013 

170. and Adult ceramide synthase deficient mice exhibit myelin sheath defects cerebellar degeneration hepatocarcinomas Imgrund 284 Biol Chem 2009 

171. Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism Mullen 52 Lipid Res 2011 

172. Ablation of ceramide synthase causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain Zigdon 288 Biol Chem 2013 

173. synthase mediates lipid - induced autophagy and hypertrophy in cardiomyocytes Russo 122 Clin Invest 2012 

174. Increased ceramide synthase mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression Erez 391 Biochem Biophys Res Commun 2010 

175. The length of lipids bound to human CD molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation McCarthy 1 Exp Med 2007 

176. Sphingoid long chain bases prevent lung infection byPseudomonas aeruginosa Pewzner 1205 Mol Med 2014 

177. Decreased level of ceramides in stratum corneum of atopic dermatitis : an etiologic factor in atopic dry skin Imokawa 523 Invest Dermatol 1991 10.1111/1523-1747.ep12470233 

     상세보기

178. Buren siRNA - mediated down - regulation of ceramide synthase leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy Separovic 2479 Anticancer Res 2012