[논문]Stem Cell Research in Pakistan; Past, Present and Future

Zahra, Sayeda Anum; Muzavir, Sayed Raheel; Ashraf, Sadia; Ahmad, Aftab

doi:10.15283/ijsc.2015.8.1.1

Stem Cell Research in Pakistan; Past, Present and Future 원문보기

International journal of stem cells, v.8 no.1, 2015년, pp.1 - 8

Zahra, Sayeda Anum (National Academy of Young Scientists (NAYS), University of the Punjab, Quaid-i-Azam Campus, Lahore, Pakistan) , Muzavir, Sayed Raheel (National Academy of Young Scientists (NAYS), University of the Punjab, Quaid-i-Azam Campus, Lahore, Pakistan) , Ashraf, Sadia (National Academy of Young Scientists (NAYS), University of the Punjab, Quaid-i-Azam Campus, Lahore, Pakistan) , Ahmad, Aftab (National Academy of Young Scientists (NAYS), University of the Punjab, Quaid-i-Azam Campus, Lahore, Pakistan)

Abstract ▼ AI-Helper

Background and ObjectivesStem cells have proved to have great therapeutic potential as stem cell treatment is replacing traditional ways of treatment in different disorders like cancer, aplastic anemia, stroke, heart disorders. The developed and developing countries are investing differently in this area of research so research output and clinical translation of research greatly vary among developed and developing countries. Present study was done to investigate the current status of stem cells research in Pakistan and ways to improve it.ResultsMany advanced countries (USA, UK and Canada etc.) are investing heavily in stem cell research and treatment. Different developing countries like Iran, Turkey and India are also following the developed countries and investing a lot in stem cells research. Pakistan is also making efforts in establishing this field to get desired benefits but unfortunately the progress is at very low pace. If Government plays an active role along with private sector, stem cell research in Pakistan can be boosted up. The numbers of publications from Pakistan are very less compared to developed and neighboring countries and Pakistan also has very less number of institutes working in this area of research.ConclusionsStem cells research is at its initial stages in Pakistan and there is great need to bring Government, academia and industry together so they could make serious efforts to promote research in this very important field. This will help millions of patients suffering from incurable disorders and will also reduce economic loss.

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참고문헌 (36)

1 Luo J Flynn JM Solnick RE Ecklund EH Matthews KR International stem cell collaboration: how disparate policies between the United States and the United Kingdom impact research PLoS One 2011 6 e17684 10.1371/journal.pone.0017684 3050923 --> 21408134

상세보기
2 Luo J Matthews KR Globalization of stem cell science: an examination of current and past collaborative research networks PLoS One 2013 8 e73598 10.1371/journal.pone.0073598 3772010 --> 24069210

상세보기
3 Weissman IL Anderson DJ Gage F Stem and progenitor cells: origins, phenotypes, lineage commitments, and trans-differentiations Annu Rev Cell Dev Biol 2001 17 387 403 11687494

상세보기
4 Smith AG Embryo-derived stem cells: of mice and men Annu Rev Cell Dev Biol 2001 17 435 462 11687496

상세보기
5 Schöler HR The Potential of Stem Cells: An Inventory Knoepffler N Schipanski D Sorgner SL Human biotechnology as Social Challenge 2007 28
6 Ulloa-Montoya F Verfaillie CM Hu WS Culture systems for pluripotent stem cells J Biosci Bioeng 2005 100 12 27 16233846
7 Thomson JA Itskovitz-Eldor J Shapiro SS Waknitz MA Swiergiel JJ Marshall VS Jones JM Embryonic stem cell lines derived from human blastocysts Science 1998 282 1145 1147 10.1126/science.282.5391.1145 9804556

상세보기
8 Larijani B Zahedi F Malek-Afzali H Medical ethics in the Islamic Republic of Iran East Mediterr Health J 2005 11 1061 1072 16761678
9 Baharvand H Ashtiani SK Valojerdi MR Shahverdi A Taee A Sabour D Establishment and in vitro differentiation of a new embryonic stem cell line from human blastocyst Differentiation 2004 72 224 229 10.1111/j.1432-0436.2004.07205005.x 15270778

상세보기
10 Jaenisch R An American scientist in Tehran Nat Reports Stem Cells 2007 10.1038/stemcells.2007.105
11 Mirzadeh H Mohagheghi MA Ahmadi H Mirkhani H Amanpour S Salehian P Cartilage tissue engineering for ear as in rabbit model with perforated polyurethane pros-thesis: in vivo assay Iranian Polymer Journal 2000 9 73 80

상세보기
12 Ghavamzadeh A Alimoghaddam K Jahani M Mousavi SA Iravani M Bahar B Khodabandeh A Khatami F Ghaffari F Jalali A Stem cell transplantation; Iranian experience Arch Iran Med 2009 12 69 72 19111033

상세보기
13 Sharma A Stem Cell Research in India: Emerging Scenario and Policy Concerns Asian Biotechnology and Development Review 2006 8 43 53
14 Savneet K Karthac C Stem cells: Concepts and prospects Current trends in Science 2009
15 Jotwani G ICMR-DBT Guidelines for Stem Cell Research New Delhi Indian Council of Medical Research 2012
16 Jose S Increasing Investment in Stem Cell Technology and Promising Research Outcomes Drives the Stem Cell Research Market According to New Report by Global Industry Analysts 2012
17 Kirstin RW Matthews Maude LR World stem cell report Regen Med 2012 7 126 129 23210825
18 Willemse L Ogbogu U Johnson S Rudnicki M World stem cell report: Canada Regen Med 2012 7 132 135 10.2217/rme.12.66 23210826

상세보기
19 Emily J Seymour C World Stem cell report Regen Med 2012 7 136 138 23210827
20 Qadir Z UK launches a new centre of excellence for stem cell research Lancet 2012 380 549 10.1016/S0140-6736(12)61312-9 22891371

상세보기
21 Park SB South Korea steps up stem-cell work: Regenerative medicine gets cash boost but stricter regulations are needed to ensure safety Nature 2012 10.1038/nature.2012.10565
22 Rodin S Domogatskaya A Ström S Hansson EM Chien KR Inzunza J Hovatta O Tryggvason K Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511 Nat Biotechnol 2010 28 611 615 10.1038/nbt.1620 20512123

상세보기
23 Rosalia MO de Carvalho Antonio Carlos Campos World Stem cell report, Brazil Regen Med 2012 7 144 147 23210829
24 Chaudry A 2004 Stem cell bioengineering Retrieved February 19, 2008 from http://www.scq.ubc.ca/stem-cell-bioengineering
25 Levicar N Dimarakis I Flores C Tracey J Gordon MY Habib NA Stem cells as a treatment for chronic liver disease and diabetes Handb Exp Pharmacol 2007 180 243 262 17554512
26 Weissman IL Stem cells: units of development, units of regeneration, and units in evolution Cell 2000 100 157 168 10.1016/S0092-8674(00)81692-X 10647940

상세보기
27 http://www.hec.gov.pk/InsideHEC/Divisions/RND/ResearchGrants/NRPU/Pages/Forms/AllItems.aspx
28 Jackson KA Majka SM Wang H Pocius J Hartley CJ Majesky MW Entman ML Michael LH Hirschi KK Goodell MA Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells J Clin Invest 2001 107 1395 1402 10.1172/JCI12150 209322 --> 11390421

상세보기
29 Robertson JA Human embryonic stem cell research: ethical and legal issues Nat Rev Genet 2001 2 74 78 10.1038/35047594 11253076

상세보기
30 Spencer DD Robbins RJ Naftolin F Marek KL Vollmer T Leranth C Roth RH Price LH Gjedde A Bunney BS Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson’s disease N Engl J Med 1992 327 1541 1548 10.1056/NEJM199211263272201 1435880

상세보기
31 Ahmad A Ziauddin A Shakoori AR Isolation and culture of human amniotic fluid stem cells (AFSCS) Pak J Health Res 2013 1 32 35
32 Khan M Ali F Mohsin S Akhtar S Mehmood A Choudhery MS Khan SN Riazuddin S Preconditioning diabetic mesenchymal stem cells with myogenic medium increases their ability to repair diabetic heart Stem Cell Res Ther 2013 4 58 10.1186/scrt207 3707006 --> 23706645

상세보기
33 Shakoori A Ahmad A Cytotoxic and Genotoxic effects of Arsenic and Lead on Human Adipose Derived Mesenchymal Stem Cells (AMSCs) J Stem Cells Regen Med 2013 9 29 36 3908312 --> 24693207

상세보기
34 Farzana T Shamsi TS Irfan M Ansari SH Baig MI Shakoor N Allogeneic peripheral blood stem cell transplantation for aplastic anaemia: a single centre experience J Pak Med Assoc 2003 53 381 384 14620309
35 Ullah K Raza S Ahmed P Chaudhry QU Satti TM Ahmed S Mirza SH Akhtar F Kamal K Akhtar FM Post-transplant infections: single center experience from the developing world Int J Infect Dis 2008 12 203 214 10.1016/j.ijid.2007.06.012 17920999

상세보기
36 Shamsi TS Hashmi K Adil S Ahmad P Irfan M Raza S Masood N Shaikh U Satti T Farzana T Ansari S The stem cell transplant program in Pakistan--the first decade Bone Marrow Transplant 2008 42 Suppl 1 S114 S117 10.1038/bmt.2008.137 18724282

상세보기

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Stem Cell Research in Pakistan; Past, Present and Future 원문보기

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