다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Experimental biology and medicine, v.240 no.7, 2015년, pp.946 - 954
Kim, Sung Hwan (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Lee, Tae Hoon (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Lee, Sang Min (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Park, Ji Hae (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Park, Keun Hyung (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Jung, Mira (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Jung, Hana (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Mohamed, Mohamed Antar Aziz (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Baek, Nam-In (Graduate School of Biotechnology and College of Life Science, Kyung Hee University, Yongin 446-701, Korea) , Chung, In Sik (Graduate School of Biotechno) , Kim, Jiyoung
AI-Helper
Cynanchum wilfordii has been traditionally used in eastern Asia for the treatment of various diseases such as gastrointestinal diseases and arteriosclerosis. Cynandione A (CA), an acetophenone, is one of major constituents from roots of C. wilfordii. In the present study, the anti-inflammatory acti...
Medzhitov, Ruslan. Origin and physiological roles of inflammation. Nature, vol.454, no.7203, 428-435.
Tabas, Ira, Glass, Christopher K.. Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities. Science, vol.339, no.6116, 166-172.
10.2174/1568010054022024
Cohen, Jonathan. The immunopathogenesis of sepsis. Nature, vol.420, no.6917, 885-891.
Lu, Yong-Chen, Yeh, Wen-Chen, Ohashi, Pamela S.. LPS/TLR4 signal transduction pathway. Cytokine, vol.42, no.2, 145-151.
Yang, Hua, Young, Donna W., Gusovsky, Fabian, Chow, Jesse C.. Cellular Events Mediated by Lipopolysaccharide-stimulated Toll-like Receptor 4. The Journal of biological chemistry, vol.275, no.27, 20861-20866.
Weinstein, S.L., Sanghera, J.S., Lemke, K, DeFranco, A.L., Pelech, S.L.. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages.. The Journal of biological chemistry, vol.267, no.21, 14955-14962.
Lawrence, Toby. The nuclear factor NF-kappaB pathway in inflammation.. Cold Spring Harbor perspectives in biology, vol.1, no.6, a001651-.
Cell Mol Immunol Liang Y 343 1 2004
Shan, Lei, Liu, Run-Hui, Shen, Yun-Heng, Zhang, Wei-Dong, Zhang, Chuan, Wu, Da-zheng, Min, Li, Su, Juan, Xu, Xi-Ke. Gastroprotective effect of a traditional Chinese herbal drug “Baishouwu” on experimental gastric lesions in rats. Journal of ethnopharmacology, vol.107, no.3, 389-394.
Choi, Deok Ho, Lee, Yun Jung, Kim, Jin Sook, Kang, Dae Gill, Lee, Ho Sub. Cynanchum wilfordii ameliorates hypertension and endothelial dysfunction in rats fed with high fat/cholesterol diets. Immunopharmacology and immunotoxicology, vol.34, no.1, 4-11.
Lee, Mi Kyeong, Yeo, Hosup, Kim, Jinwoong, Kim, YOUNG CHOONG. Protection of Rat Hepatocytes Exposed to CCl4 In-vitro by Cynandione A, a Biacetophenone from Cynanchum wilfordii. Journal of pharmacy and pharmacology, vol.52, no.3, 341-345.
10.1002/(SICI)1097-4547(20000115)59:2<259::AID-JNR12>3.0.CO;2-3
Jiang, Yanfu, Choi, Hyun-Gyu, Li, Ying, Park, Yu-Mi, Lee, Jong-Hwa, Kim, Do-Hoon, Lee, Je-Hyun, Son, Jong-Keun, Na, Min-Kyun, Lee, Seung-Ho. Chemical Constituents of Cynanchum wilfordii and the Chemotaxonomy of Two Species of the Family Asclepiadacease, C. wilfordii and C. auriculatum. Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, vol.34, no.12, 2021-2027.
Lee, Tae Hoon, Jung, Mira, Bang, Myun-Ho, Chung, Dae Kyun, Kim, Jiyoung. Inhibitory effects of a spinasterol glycoside on lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines via down-regulating MAP kinase pathways and NF-κB activation in RAW264.7 macrophage cells. International immunopharmacology, vol.13, no.3, 264-270.
Livak, Kenneth J., Schmittgen, Thomas D.. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔC T Method. Methods, vol.25, no.4, 402-408.
Kobayashi, Yoshiro. The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation. Journal of leukocyte biology, vol.88, no.6, 1157-1162.
Hickey, Michael J., Sihota, Elaine, Amrani, Abdelaziz, Santamaria, Pere, Zbytnuik, Lori D., Ng, Ella S.M., Ho, Winnie, Sharkey, Keith A., Kubes, Paul. Inducible nitric oxide synthase (iNOS) in endotoxemia: chimeric mice reveal different cellular sources in various tissues. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol.16, no.9, 1141-1143.
Libby, Peter, Ridker, Paul M., Maseri, Attilio. Inflammation and Atherosclerosis. Circulation, vol.105, no.9, 1135-1143.
Glass, Christopher K., Saijo, Kaoru, Winner, Beate, Marchetto, Maria Carolina, Gage, Fred H.. Mechanisms Underlying Inflammation in Neurodegeneration. Cell, vol.140, no.6, 918-934.
Yi, Peng-fei, Wu, Yi-chun, Dong, Hai-bing, Guo, Yang, Wei, Qian, Zhang, Cui, Song, Zhou, Qin, Qian-qian, Lv, Shuang, Wu, Shuai-cheng, Fu, Ben-dong. Peimine impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK in LPS-induced RAW264.7 macrophages. Immunopharmacology and immunotoxicology, vol.35, no.5, 567-572.
Guha, Mausumee, Mackman, Nigel. LPS induction of gene expression in human monocytes. Cellular signalling, vol.13, no.2, 85-94.
Surh, Young-Joon, Chun, Kyung-Soo, Cha, Hyun-Ho, Han, Seong Su, Keum, Young-Sam, Park, Kwang-Kyun, Lee, Sang Sup. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-κB activation. Mutation research. Fundamental and molecular mechanisms of mutagenesis, vol.480, 243-268.
Kundu, Joydeb Kumar, Shin, Young Kee, Surh, Young-Joon. Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-κB and AP-1 as prime targets. Biochemical pharmacology, vol.72, no.11, 1506-1515.
May, Michael J, Ghosh, Sankar. Signal transduction through NF-κB. Immunology today, vol.19, no.2, 80-88.
Murakami, Akira, Ohigashi, Hajime. Targeting NOX, INOS and COX-2 in inflammatory cells: Chemoprevention using food phytochemicals. International journal of cancer: Journal international du cancer, vol.121, no.11, 2357-2363.
Lin, Yu-Li, Lin, Jen-Kun. (−)-Epigallocatechin-3-gallate Blocks the Induction of Nitric Oxide Synthase by Down-Regulating Lipopolysaccharide-Induced Activity of Transcription Factor Nuclear Factor-κB. Molecular pharmacology, vol.52, no.3, 465-472.
Brouet, I., Ohshima, H.. Curcumin, an Anti-tumor Promoter and Anti-inflammatory Agent, Inhibits Induction of Nitric Oxide Synthase in Activated Macrophages. Biochemical and biophysical research communications, vol.206, no.2, 533-540.
Yue, Rongcai, Yuan, Xing, Liu, Xiaojun, Zhang, Jigang, Jiang, Peng, He, Cheng, Shan, Lei, Yu, Yizhi, Zhang, Weidong. Cynandione A mitigates ischemic injuries in rats with cerebral ischemia. Journal of neurochemistry, vol.121, no.3, 451-464.
Nie, Zhongzhen, Mei, Yun, Ford, Mary, Rybak, Leonard, Marcuzzi, Adrianna, Ren, Hongzu, Stiles, Gary L., Ramkumar, Vickram. Oxidative Stress Increases A1Adenosine Receptor Expression by Activating Nuclear Factor κB. Molecular pharmacology, vol.53, no.4, 663-669.
Gupta, Subash C., Sundaram, Chitra, Reuter, Simone, Aggarwal, Bharat B.. Inhibiting NF-κB activation by small molecules as a therapeutic strategy. Biochimica et biophysica acta. Gene regulatory mechanisms, vol.1799, no.10, 775-787.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
저자가 공개 리포지터리에 출판본, post-print, 또는 pre-print를 셀프 아카이빙 하여 자유로운 이용이 가능한 논문
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.