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International immunopharmacology, v.30, 2016년, pp.50 - 56
Zhao, H. , Liu, Z. , Liu, W. , Han, X. , Zhao, M.
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Sepsis is a complex condition with unacceptable mortality. Betulin is a natural extract with multiple bioactivities. This study aims to evaluate the potential effects of betulin on lung and liver injury in sepsis. Cecal ligation and puncture was used to establish the rat model of sepsis. A single do...
Crit. Care Med. Damas 17 975 1989 10.1097/00003246-198910000-00001 Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans
Crit. Care Med. Marty 22 673 1994 10.1097/00003246-199404000-00025 Circulating interleukin-8 concentrations in patients with multiple organ failure of septic and nonseptic origin
Ann. Intern. Med. Casey 119 771 1993 10.7326/0003-4819-119-8-199310150-00001 Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome
J. Clin. Invest. Wakabayashi 87 1925 1991 10.1172/JCI115218 Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli
Crit. Care Gu 15 R153 2011 10.1186/cc10283 Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice
Crit. Care Clin. Nduka 25 677 2009 10.1016/j.ccc.2009.08.002 The pathophysiology of septic shock
Crit. Care Med. Cinel 37 291 2009 10.1097/CCM.0b013e31819267fb Molecular biology of inflammation and sepsis: a primer
N. Engl. J. Med. Pro 370 1683 2014 10.1056/NEJMoa1401602 A randomized trial of protocol-based care for early septic shock
PLoS ONE Zhou 9 2014 Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China
Crit. Care Nurs. Clin. North Am. Krau 19 87 2007 10.1016/j.ccell.2006.11.002 Making sense of multiple organ dysfunction syndrome
Intensive Care Med. Vincent 22 707 1996 10.1007/BF01709751 The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine
Eur. J. Pharm. Sci. Alakurtti 29 1 2006 10.1016/j.ejps.2006.04.006 Pharmacological properties of the ubiquitous natural product betulin
Microb. Pathog. Wu 75 21 2014 10.1016/j.micpath.2014.08.005 Betulin protects mice from bacterial pneumonia and acute lung injury
Toxicology Szuster-Ciesielska 280 152 2011 10.1016/j.tox.2010.12.006 Betulin and betulinic acid attenuate ethanol-induced liver stellate cell activation by inhibiting reactive oxygen species (ROS), cytokine (TNF-alpha, TGF-beta) production and by influencing intracellular signaling
Dev. Comp. Immunol. Zong 52 123 2015 10.1016/j.dci.2015.05.006 LFP-20, a porcine lactoferrin peptide, ameliorates LPS-induced inflammation via the MyD88/NF-kappaB and MyD88/MAPK signaling pathways
Drug Des. Devel. Ther. Zhao 9 1663 2015 10.2147/DDDT.S75862 Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model
J. Surg. Res. Hu 194 528 2015 10.1016/j.jss.2014.10.027 Ursolic acid improves survival and attenuates lung injury in septic rats induced by cecal ligation and puncture
J. Surg. Res. Zhou 195 559 2015 10.1016/j.jss.2015.02.026 Protective effect of astaxanthin against multiple organ injury in a rat model of sepsis
Int. J. Clin. Exp. Yorulmaz 8 3640 2015 Effect of simvastatin on mitochondrial enzyme activities, ghrelin, hypoxia-inducible factor 1alpha in hepatic tissue during early phase of sepsis
Shock Lomas-Neira 37 611 2012 10.1097/SHK.0b013e318254fa6a The role and source of tumor necrosis factor-alpha in hemorrhage-induced priming for septic lung injury
Am. J. Respir. Crit. Care Med. Vanden Berghe 189 282 2014 10.1164/rccm.201308-1535OC Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock
J. Infect. Chemother. Aikawa 19 931 2013 10.1007/s10156-013-0612-y A phase II study of polyclonal anti-TNF-alpha (AZD9773) in Japanese patients with severe sepsis and/or septic shock
Int. Immunopharmacol. Huh 9 230 2009 10.1016/j.intimp.2008.11.016 Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis
Eur. Rev. Med. Pharmacol. Sci. Zhang 19 455 2015 Betulin inhibits pro-inflammatory cytokines expression through activation STAT3 signaling pathway in human cardiac cells
Exp. Cell Res. Einck 156 295 1985 10.1016/0014-4827(85)90539-7 The intracellular distribution and function of the high mobility group chromosomal proteins
Science Bianchi 243 1056 1989 10.1126/science.2922595 Specific recognition of cruciform DNA by nuclear protein HMG1
Curr. Opin. Genet. Dev. Agresti 13 170 2003 10.1016/S0959-437X(03)00023-6 HMGB proteins and gene expression
Annu. Rev. Immunol. Andersson 29 139 2011 10.1146/annurev-immunol-030409-101323 HMGB1 is a therapeutic target for sterile inflammation and infection
Science Wang 285 248 1999 10.1126/science.285.5425.248 HMG-1 as a late mediator of endotoxin lethality in mice
Nature Scaffidi 418 191 2002 10.1038/nature00858 Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
Crit. Care Med. Sunden-Cullberg 33 564 2005 10.1097/01.CCM.0000155991.88802.4D Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock
Intensive Care Med. Karlsson 34 1046 2008 10.1007/s00134-008-1032-9 HMGB1 as a predictor of organ dysfunction and outcome in patients with severe sepsis
Crit. Care Med. Susa 37 2619 2009 10.1097/CCM.0b013e3181a930f7 Neutralization of receptor for advanced glycation end-products and high mobility group box-1 attenuates septic diaphragm dysfunction in rats with peritonitis
Clin. Chem. Chen 45 7 1999 10.1093/clinchem/45.1.7 New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases
Am. J. Physiol. Lung Cell. Mol. Physiol. Liu 290 L622 2006 10.1152/ajplung.00477.2005 NF-kappa B activation as a pathological mechanism of septic shock and inflammation
J. Trauma Browder 46 590 1999 10.1097/00005373-199904000-00006 Early activation of pulmonary nuclear factor kappaB and nuclear factor interleukin-6 in polymicrobial sepsis
Ann. Surg. Williams 230 95 1999 10.1097/00000658-199907000-00014 Early activation of hepatic NFkappaB and NF-IL6 in polymicrobial sepsis correlates with bacteremia, cytokine expression, and mortality
Surgery Williams 126 54 1999 10.1067/msy.1999.99058 Inhibiting early activation of tissue nuclear factor-kappa B and nuclear factor interleukin 6 with (1->3)-beta-d-glucan increases long-term survival in polymicrobial sepsis
Mol. Med. Rep. Jin 10 631 2014 10.3892/mmr.2014.2299 Effect of siRNA against NF-kappaB on sepsisinduced acute lung injury in a mouse model
Eur. J. Pharmacol. Kim 649 369 2010 10.1016/j.ejphar.2010.09.032 Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-kappaB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages
J. Surg. Res. O'Sullivan 152 46 2009 10.1016/j.jss.2008.04.030 NF-kappaB and p38 MAPK inhibition improve survival in endotoxin shock and in a cecal ligation and puncture model of sepsis in combination with antibiotic therapy
Br. J. Pharmacol. Wang 2015 10.1111/bph.13221 MD-2 as the target of a novel small molecule, L6H21, in the attenuation of LPS-induced inflammatory response and sepsis
J. Cell Biol. Palumbo 179 33 2007 10.1083/jcb.200704015 Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation
J. Surg. Res. Cain 83 7 1999 10.1006/jsre.1998.5548 p38 MAPK inhibition decreases TNF-alpha production and enhances postischemic human myocardial function
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