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Lactobacillus plantarum NCU116 Attenuates Cyclophosphamide-Induced Immunosuppression and Regulates Th17/Treg Cell Immune Responses in Mice

Journal of agricultural and food chemistry, v.64 no.6, 2016년, pp.1291 - 1297  

Xie, Junhua (State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047,) ,  Nie, Shaoping (State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047,) ,  Yu, Qiang (State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047,) ,  Yin, Junyi (State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047,) ,  Xiong, Tao (State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047,) ,  Gong, Deming (State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047,) ,  Xie, Mingyong (State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047,)

Abstract AI-Helper 아이콘AI-Helper

The balance of T helper cells 17 (Th17)/regulatory T cells (Treg) plays a key role in maintaining a normal immune response. It is well-known that cyclophosphamide (CTX) applied at high dose often damages the immune system by inhibiting immune cell proliferation. In this study, the immunomodulating e...

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