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Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription 원문보기

International journal of molecular medicine, v.37 no.3, 2016년, pp.613 - 622  

PARK, WOO-JAE (Department of Biochemistry, School of Medicine, Gachon University, Incheon 406-799, Republic of Korea) ,  KIM, SO-YEON (Department of Biochemistry, School of Medicine, Ewha Womans University, Yang Cheon-Gu, Seoul 158-710, Republic of Korea) ,  KIM, YE-RYUNG (Department of Biochemistry, School of Medicine, Ewha Womans University, Yang Cheon-Gu, Seoul 158-710, Republic of Korea) ,  PARK, JOO-WON (Department of Biochemistry, School of Medicine, Ewha Womans University, Yang Cheon-Gu, Seoul 158-710, Republic of Korea)

Abstract AI-Helper 아이콘AI-Helper

Acute liver failure, i.e., the fatal deterioration of liver function, is the most common indication that emergency liver transplantation is necessary. Moreover, in the USA, drug-induced liver injury (DILI), including acetaminophen (APAP)-induced hepatotoxicity, is the main cause of acute liver failu...

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참고문헌 (51)

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