참고문헌 (49)

1. Alzheimer’s Association. 2015 Alzheimer’s disease facts and figures . Alzheimers Dement. J. Alzheimers Assoc. 11 , 332 – 384 ( 2015 ). 

2. Ortman J. M. , Velkoff V. A. & Hogan H. An Aging Nation: The Older Population in the United States . U.S. Department of Commerce. Economics and Statistics Administration. U.S. Census Bureau (2014) (Date of access: 11/25/2015). https://www.census.gov/prod/2014pubs/p25-1140.pdf . 

3. Hayes T. L. . Unobtrusive assessment of activity patterns associated with mild cognitive impairment . Alzheimers Dement. J. Alzheimers Assoc. 4 , 395 – 405 ( 2008 ). 

4. Aybek S. . Fractal temporal organisation of motricity is altered in major depression . Psychiatry Res. 200 , 288 – 293 ( 2012 ). 22542087 

   상세보기

5. Indic P. . Multi-scale motility amplitude associated with suicidal thoughts in major depression . PloS One 7 , e38761 ( 2012 ). 22701706 

   상세보기

6. Hu K. . Non-random fluctuations and multi-scale dynamics regulation of human activity . Phys. -Stat. Mech. Its Appl. 337 , 307 – 318 ( 2004 ). 

7. Amaral L. a. N. . Power law temporal auto-correlations in day-long records of human physical activity and their alteration with disease . Europhys. Lett. 66 , 448 – 454 ( 2004 ). 

   상세보기

8. Ohashi K. . Decreased fractal correlation in diurnal physical activity in chronic fatigue syndrome . Methods Inf. Med. 43 , 26 – 29 ( 2004 ). 15026831 

   상세보기

9. Hu K. , Van Someren E. J. W. , Shea S. A. & Scheer F. A. J. L. Reduction of scale invariance of activity fluctuations with aging and Alzheimer’s disease: Involvement of the circadian pacemaker . Proc. Natl. Acad. Sci. USA 106 , 2490 – 2494 ( 2009 ). 19202078 

   상세보기

10. Hu K. , Harper D. G. , Shea S. A. , Stopa E. G. & Scheer F. A. J. L. Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia . Sci. Rep. 3 , 2229 ( 2013 ). 23863985 

11. Indic P. . Scaling behavior of human locomotor activity amplitude: association with bipolar disorder . PloS One 6 , e20650 ( 2011 ). 21655197 

    상세보기

12. Krane-Gartiser K. , Henriksen T. E. G. , Morken G. , Vaaler A. & Fasmer O. B. Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder . PloS One 9 , e89574 ( 2014 ). 24586883 

    상세보기

13. Sano W. . Enhanced persistency of resting and active periods of locomotor activity in schizophrenia . PloS One 7 , e43539 ( 2012 ). 22952701 

14. Nakamura T. . Of mice and men–universality and breakdown of behavioral organization . PloS One 3 , e2050 ( 2008 ). 18446212 

    상세보기

15. Pittman-Polletta B. R. , Scheer F. A. J. L. , Butler M. P. , Shea S. A. & Hu K. The role of the circadian system in fractal neurophysiological control . Biol. Rev. 88 , 873 – 894 ( 2013 ). 23573942 

    상세보기

16. Lim A. S. P. & Saper C. B. Sleep, circadian rhythms, and dementia . Ann. Neurol. 70 , 677 – 679 ( 2011 ). 22162052 

    상세보기

17. Monteleone P. & Maj M. The circadian basis of mood disorders: recent developments and treatment implications . Eur. Neuropsychopharmacol. J. Eur. Coll. Neuropsychopharmacol. 18 , 701 – 711 ( 2008 ). 

18. Albrecht U. Circadian clocks and mood-related behaviors . Handb. Exp. Pharmacol. 227 – 239 , 10.1007/978-3-642-25950-0_9 ( 2013 ). 23604481 

    상세보기

19. Salvatore P. , Indic P. , Murray G. & Baldessarini R. J. Biological rhythms and mood disorders . Dialogues Clin. Neurosci. 14 , 369 – 379 ( 2012 ). 23393414 

20. Tranah G. J. . Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women . Ann. Neurol. 70 , 722 – 732 ( 2011 ). 22162057 

    상세보기

21. Ju Y.-E. S. . Sleep quality and preclinical Alzheimer disease . JAMA Neurol. 70 , 587 – 593 ( 2013 ). 23479184 

    상세보기

22. Lim A. S. P. , Kowgier M. , Yu L. , Buchman A. S. & Bennett D. A. Sleep Fragmentation and the Risk of Incident Alzheimer’s Disease and Cognitive Decline in Older Persons . Sleep 36 , 1027 – 1032 ( 2013 ). 23814339 

    상세보기

23. Van Cauter E. & Turek F. W. Depression: a disorder of timekeeping? Perspect. Biol. Med. 29 , 510 – 519 ( 1986 ). 3092181 

    상세보기

24. Souêtre E. . Circadian rhythms in depression and recovery: evidence for blunted amplitude as the main chronobiological abnormality . Psychiatry Res. 28 , 263 – 278 ( 1989 ). 2762432 

    상세보기

25. Li J. Z. . Circadian patterns of gene expression in the human brain and disruption in major depressive disorder . Proc. Natl. Acad. Sci. USA 110 , 9950 – 9955 ( 2013 ). 23671070 

    상세보기

26. Forbes D. , Blake C. M. , Thiessen E. J. , Peacock S. & Hawranik P. Light therapy for improving cognition, activities of daily living, sleep, challenging behaviour, and psychiatric disturbances in dementia . Cochrane Database Syst. Rev. 2 , CD003946 ( 2014 ). 

27. Alzoubi K. H. . Chronic Melatonin Treatment Prevents Memory Impairment Induced by Chronic Sleep Deprivation . Mol. Neurobiol. , 10.1007/s12035-015-9286-z ( 2015 ). 

    상세보기

28. Swaab D. F. , Van Someren E. J. , Zhou J. N. & Hofman M. A. Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic nucleus . Prog. Brain Res. 111 , 349 – 368 ( 1996 ). 8990925 

    상세보기

29. Wang J. L. . Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans . Ann. Neurol. 78 , 317 – 322 ( 2015 ). 25921596 

    상세보기

30. Hu K. , Scheer F. A. J. L. , Ivanov P. C. , Buijs R. M. & Shea S. A. The suprachiasmatic nucleus functions beyond circadian rhythm generation . Neuroscience 149 , 508 – 517 ( 2007 ). 17920204 

    상세보기

31. Riemersma-van der Lek R. F. . Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial . JAMA 299 , 2642 – 2655 ( 2008 ). 18544724 

    상세보기

32. Robinson L. , Tang E. & Taylor J.-P. Dementia: timely diagnosis and early intervention . BMJ 350 , h3029 ( 2015 ). 26079686 

33. Goldberger A. L. . Fractal dynamics in physiology: alterations with disease and aging . Proc. Natl. Acad. Sci. USA 99 Suppl 1, 2466 – 2472 ( 2002 ). 11875196 

    상세보기

34. Hsieh W.-H. . Simulated shift work in rats perturbs multiscale regulation of locomotor activity . J. R. Soc. Interface 11 , 20140318 ( 2014 ). 24829282 

    상세보기

35. Bennett S. & Thomas A. J. Depression and dementia: cause, consequence or coincidence? Maturitas 79 , 184 – 190 ( 2014 ). 24931304 

    상세보기

36. Borsje P. , Wetzels R. B. , Lucassen P. L. , Pot A. M. & Koopmans R. T. The course of neuropsychiatric symptoms in community-dwelling patients with dementia: a systematic review . Int. Psychogeriatr. IPA 27 , 385 – 405 ( 2015 ). 

37. Association A. P. Diagnostic and Statistical Manual of Mental Disorders , 4th Edition, Text Revision. (American Psychiatric Association, 2000 ). 

38. Zhdanova I. V. , Lynch H. J. & Wurtman R. J. Melatonin: a sleep-promoting hormone . Sleep 20 , 899 – 907 ( 1997 ). 9415953 

39. Singer C. . A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer’s disease . Sleep 26 , 893 – 901 ( 2003 ). 14655926 

40. Middleton B. , Stone B. M. & Arendt J. Human circadian phase in 12:12 h, 200: <8 lux and 1000: <8 lux light-dark cycles, without scheduled sleep or activity . Neurosci. Lett. 329 , 41 – 44 ( 2002 ). 12161258 

    상세보기

41. Van Someren E. J. , Kessler A. , Mirmiran M. & Swaab D. F. Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients . Biol. Psychiatry 41 , 955 – 963 ( 1997 ). 9110101 

    상세보기

42. Folstein M. F. , Folstein S. E. & McHugh P. R. ‘Mini-mental state’. A practical method for grading the cognitive state of patients for the clinician . J. Psychiatr. Res. 12 , 189 – 198 ( 1975 ). 1202204 

    상세보기

43. Alexopoulos G. S. , Abrams R. C. , Young R. C. & Shamoian C. A. Cornell Scale for Depression in Dementia . Biol. Psychiatry 23 , 271 – 284 ( 1988 ). 3337862 

    상세보기

44. Harwood D. G. , Ownby R. L. , Barker W. W. & Duara R. The factor structure of the Cornell Scale for Depression in Dementia among probable Alzheimer’s disease patients . Am. J. Geriatr. Psychiatry Off. J. Am. Assoc. Geriatr. Psychiatry 6 , 212 – 220 ( 1998 ). 

45. Lawton M. P. , Van Haitsma K. & Klapper J. Observed affect in nursing home residents with Alzheimer’s disease . J. Gerontol. B. Psychol. Sci. Soc. Sci. 51 , P3 – 14 ( 1996 ). 8548515 

46. Helmes E. , Csapo K. G. & Short J. A. Standardization and validation of the Multidimensional Observation Scale for Elderly Subjects (MOSES) . J. Gerontol. 42 , 395 – 405 ( 1987 ). 3598087 

    상세보기

47. Peng C. K. . Fractal mechanisms and heart rate dynamics. Long-range correlations and their breakdown with disease . J. Electrocardiol. 28 Suppl, 59 – 65 ( 1995 ). 8656130 

48. Hu K. , Ivanov P. C. , Chen Z. , Carpena P. & Stanley H. E. Effect of trends on detrended fluctuation analysis . Phys. Rev. E 64 , 11114 ( 2001 ). 

49. Lo M. T. . Interactive Effects of Dorsomedial Hypothalamic Nucleus and Time-Restricted Feeding on Fractal Motor Activity Regulation . Front. Physiol. 7 , 174 ( 2016 ). 27242548