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Generation and characterization of anti-Adeno-associated virus serotype 8 (AAV8) and anti-AAV9 monoclonal antibodies 원문보기

Journal of virological methods, v.236, 2016년, pp.105 - 110  

Tseng, Y.S. ,  Vliet, K.V. ,  Rao, L. ,  McKenna, R. ,  Byrne, B.J. ,  Asokan, A. ,  Agbandje-McKenna, M.

Abstract AI-Helper 아이콘AI-Helper

Adeno-associated viruses (AAVs) are promising viral vectors for therapeutic gene delivery, and the approval of an AAV1 vector for the treatment of lipoprotein lipase deficiency has heralded a new and exciting era for this system. However, preclinical and clinical studies show that neutralization fro...

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