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[해외논문] Gene therapy using plasmid DNA-encoded anti-HER2 antibody for cancers that overexpress HER2 원문보기

Cancer gene therapy, v.23 no.10, 2016년, pp.341 - 347  

Kim, H (Department of Biology, College of National Science, Kangwon National University , Chuncheon, Korea) ,  Danishmalik, S N (BK21 Plus Graduate Program and Department of Microbiology, School of Medicine, Kangwon National University , Chuncheon, Korea) ,  Hwang, H (Department of Systems Immunology, College of Biomedical Science, Kangwon National University , Chuncheon, Korea) ,  Sin, J-I (BK21 Plus Graduate Program and Department of Microbiology, School of Medicine, Kangwon National University , Chuncheon, Korea) ,  Oh, J (Research Center, GeneOne Life Science , Seoul, Korea) ,  Cho, Y (Research Center, GeneOne Life Science , Seoul, Korea) ,  Lee, H (Research Center, GeneOne Life Science , Seoul, Korea) ,  Jeong, M (Research Center, GeneOne Life Science , Seoul, Korea) ,  Kim, S-H (Department of Systems Immunology, College of Biomedical Science, Kangwon National University , Chunch) ,  Hong, H J

Abstract AI-Helper 아이콘AI-Helper

Plasmid DNA-encoded antibodies, or DNA-based monoclonal antibodies (dMAbs), are delivered by intramuscular injection and in vivo electroporation (EP) and are effective in virus neutralization, although they have not been evaluated for tumor gene therapy. Here we investigated whether a dMAb was appro...

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