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Quassinoids isolated from Brucea javanica inhibit pepper mottle virus in pepper

Virus research : an international journal of molecular and cellular virology, v.227, 2017년, pp.49 - 56  

Ryu, Seung Mok (Department of Biosystems and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea) ,  Kwon, Jaeyoung (Natural Constituents Research Center, Korea Institute of Science and Technology (KIST), Gangneung, 25451, Republic of Korea) ,  Seo, Young Hye (Department of Biosystems and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea) ,  Song, Eun Gyeong (Plant Virus GenBank, Department of Horticulture, Biotechnology and Landscape Architecture, Seoul Women’s University, Seoul, 01797, Republic of Korea) ,  Hong, Seong Su (Bio-Center, Gyeonggi Institute of Science & Technology Promotion, Suwon, 16229, Republic of Korea) ,  Kim, Beom Seok (Department of Biosystems and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 02841, Republic of Korea) ,  Hong, Jin Sung (Department of Applied Biology, College of Agriculture and Life Sciences, Kangwon National University, Chunchon, 24341, Republic of Korea) ,  Ryu, Ki Hyun (Plant Virus GenBank, Department of Horticulture, Biotechnology) ,  Lee, Dongho

Abstract AI-Helper 아이콘AI-Helper

A green fluorescent protein (GFP)-tagged pepper mottle virus (PepMoV) based leaf-disc method and systemic host method were developed to identify antiviral agents. Preliminary experiments using a PepMoV-GFP based leaf-disc method led to the isolation of five quassinoids, including brusatol (1), bruce...

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참고문헌 (23)

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  21. Chem. Pharm. Bull. Tamura 48 876 2000 10.1248/cpb.48.876 Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation Introduction of lipophilic side chain and esterification of diosphenol 

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