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Hovenia Dulcis Extract Reduces Lipid Accumulation in Oleic Acid‐Induced Steatosis of Hep G2 Cells via Activation of AMPK and PPARα/CPT‐1 Pathway and in Acute Hyperlipidemia Mouse Model

Phytotherapy research : PTR, v.31 no.1, 2017년, pp.132 - 139  

Kim, Bonglee (College of Korean Medicine, Kyung Hee University, Seoul, 130‐) ,  Woo, Moon‐Jea (701, Korea) ,  Park, Chul‐Soo (Kwang dong Pharmaceutical Co., Ltd., Seoul, 137‐) ,  Lee, Sang‐Hun (875, Korea) ,  Kim, Jin‐Soo (Kwang dong Pharmaceutical Co., Ltd., Seoul, 137‐) ,  Kim, Boim (875, Korea) ,  An, Seho (Kwang dong Pharmaceutical Co., Ltd., Seoul, 137‐) ,  Kim, Sung‐Hoon (875, Korea)

Abstract AI-Helper 아이콘AI-Helper

Hovenia dulcis Thunb. (HDT) was known to have anti‐fatigue, anti‐diabetes, neuroprotective, and hepatoprotective effects. In the present study, the anti‐fatty liver mechanism of HDT was elucidated in oleic acid (OA)‐treated Hep G2 cells and acute hyperlipidemia mouse model us...

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