$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Hendra and Nipah Virus Infection in Cultured Human Olfactory Epithelial Cells 원문보기

MSphere, v.2 no.3, 2017년, pp.e00252-17 -   

Borisevich, Viktoriya (Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA) ,  Ozdener, Mehmet Hakan (Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA) ,  Malik, Bilal (Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA) ,  Rockx, Barry (Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA)

Abstract AI-Helper 아이콘AI-Helper

ABSTRACTHenipaviruses are emerging zoonotic viruses and causative agents of encephalitis in humans. However, the mechanisms of entry into the central nervous system (CNS) in humans are not known. Here, we evaluated the possible role of olfactory epithelium in virus entry into the CNS. We characteriz...

주제어

참고문헌 (22)

  1. 1. Rockx B , Winegar R , Freiberg AN 2012 Recent progress in henipavirus research: molecular biology, genetic diversity, animal models . Antiviral Res 95 : 135 – 149 . doi: 10.1016/j.antiviral.2012.05.008 . 22643730 

  2. 2. Goh KJ , Tan CT , Chew NK , Tan PS , Kamarulzaman A , Sarji SA , Wong KT , Abdullah BJ , Chua KB , Lam SK 2000 Clinical features of Nipah virus encephalitis among pig farmers in Malaysia . N Engl J Med 342 : 1229 – 1235 . doi: 10.1056/NEJM200004273421701 . 10781618 

  3. 3. Hossain MJ , Gurley ES , Montgomery JM , Bell M , Carroll DS , Hsu VP , Formenty P , Croisier A , Bertherat E , Faiz MA , Azad AK , Islam R , Molla MA , Ksiazek TG , Rota PA , Comer JA , Rollin PE , Luby SP , Breiman RF 2008 Clinical presentation of Nipah virus infection in Bangladesh . Clin Infect Dis 46 : 977 – 984 . doi: 10.1086/529147 . 18444812 

  4. 4. Playford EG , McCall B , Smith G , Slinko V , Allen G , Smith I , Moore F , Taylor C , Kung YH , Field H 2010 Human Hendra virus encephalitis associated with equine outbreak, Australia, 2008 . Emerg Infect Dis 16 : 219 – 223 . doi: 10.3201/eid1602.090552 . 20113550 

  5. 5. Gurley ES , Montgomery JM , Hossain MJ , Bell M , Azad AK , Islam MR , Molla MA , Carroll DS , Ksiazek TG , Rota PA , Lowe L , Comer JA , Rollin P , Czub M , Grolla A , Feldmann H , Luby SP , Woodward JL , Breiman RF 2007 Person-to-person transmission of Nipah virus in a Bangladeshi community . Emerg Infect Dis 13 : 1031 – 1037 . doi: 10.3201/eid1307.061128 . 18214175 

  6. 6. Rahman MA , Hossain MJ , Sultana S , Homaira N , Khan SU , Rahman M , Gurley ES , Rollin PE , Lo MK , Comer JA , Lowe L , Rota PA , Ksiazek TG , Kenah E , Sharker Y , Luby SP 2012 Date palm sap linked to Nipah virus outbreak in Bangladesh, 2008 . Vector Borne Zoonotic Dis 12 : 65 – 72 . doi: 10.1089/vbz.2011.0656 . 21923274 

  7. 7. Selvey LA , Wells RM , McCormack JG , Ansford AJ , Murray K , Rogers RJ , Lavercombe PS , Selleck P , Sheridan JW 1995 Infection of humans and horses by a newly described morbillivirus . Med J Aust 162 : 642 – 645 . 7603375 

  8. 8. Parashar UD , Sunn LM , Ong F , Mounts AW , Arif MT , Ksiazek TG , Kamaluddin MA , Mustafa AN , Kaur H , Ding LM , Othman G , Radzi HM , Kitsutani PT , Stockton PC , Arokiasamy J , Gary HE Jr , Anderson LJ 2000 Case-control study of risk factors for human infection with a new zoonotic paramyxovirus, Nipah virus, during a 1998–1999 outbreak of severe encephalitis in Malaysia . J Infect Dis 181 : 1755 – 1759 . doi: 10.1086/315457 . 10823779 

  9. 9. Rockx B , Brining D , Kramer J , Callison J , Ebihara H , Mansfield K , Feldmann H 2011 Clinical outcome of Henipavirus infection in hamsters is determined by the route and dose of infection . J Virol 85 : 7658 – 7671 . doi: 10.1128/JVI.00473-11 . 21593160 

  10. 10. Weingartl H , Czub S , Copps J , Berhane Y , Middleton D , Marszal P , Gren J , Smith G , Ganske S , Manning L , Czub M 2005 Invasion of the central nervous system in a porcine host by Nipah virus . J Virol 79 : 7528 – 7534 . doi: 10.1128/JVI.79.12.7528-7534.2005 . 15919907 

  11. 11. Munster VJ , Prescott JB , Bushmaker T , Long D , Rosenke R , Thomas T , Scott D , Fischer ER , Feldmann H , de Wit E 2012 Rapid Nipah virus entry into the central nervous system of hamsters via the olfactory route . Sci Rep 2 : 736 . doi: 10.1038/srep00736 . 23071900 

  12. 12. Dups J , Middleton D , Yamada M , Monaghan P , Long F , Robinson R , Marsh GA , Wang LF 2012 A new model for Hendra virus encephalitis in the mouse . PLoS One 7 : e40308 . doi: 10.1371/journal.pone.0040308 . 22808132 

  13. 13. Sarji SA , Abdullah BJ , Goh KJ , Tan CT , Wong KT 2000 MR imaging features of Nipah encephalitis . AJR Am J Roentgenol 175 : 437 – 442 . doi: 10.2214/ajr.175.2.1750437 . 10915690 

  14. 14. Rawson NE , Ozdener MH 2013 Primary culture of the human olfactory neuroepithelium . Methods Mol Biol 945 : 81 – 93 . doi: 10.1007/978-1-62703-125-7_6 . 23097102 

  15. 15. Borgmann-Winter KE , Rawson NE , Wang HY , Wang H , Macdonald ML , Ozdener MH , Yee KK , Gomez G , Xu J , Bryant B , Adamek G , Mirza N , Pribitkin E , Hahn CG 2009 Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics . Neuroscience 158 : 642 – 653 . doi: 10.1016/j.neuroscience.2008.09.059 . 18996445 

  16. 16. Hahn CG , Han LY , Rawson NE , Mirza N , Borgmann-Winter K , Lenox RH , Arnold SE 2005 In vivo and in vitro neurogenesis in human olfactory epithelium . J Comp Neurol 483 : 154 – 163 . doi: 10.1002/cne.20424 . 15678478 

  17. 17. Gomez G , Rawson NE , Hahn CG , Michaels R , Restrepo D 2000 Characteristics of odorant elicited calcium changes in cultured human olfactory neurons . J Neurosci Res 62 : 737 – 749 . doi: 10.1002/1097-4547(20001201)62:5 3.0.CO;2-A . 11104513 

  18. 18. Escaffre O , Borisevich V , Carmical JR , Prusak D , Prescott J , Feldmann H , Rockx B 2013 Henipavirus pathogenesis in human respiratory epithelial cells . J Virol 87 : 3284 – 3294 . doi: 10.1128/JVI.02576-12 . 23302882 

  19. 19. Dalton PH , Opiekun RE , Gould M , McDermott R , Wilson T , Maute C , Ozdener MH , Zhao K , Emmett E , Lees PS , Herbert R , Moline J 2010 Chemosensory loss: functional consequences of the world trade center disaster . Environ Health Perspect 118 : 1251 – 1256 . doi: 10.1289/ehp.1001924 . 20478761 

  20. 20. Turner JH , Liang KL , May L , Lane AP 2010 Tumor necrosis factor alpha inhibits olfactory regeneration in a transgenic model of chronic rhinosinusitis-associated olfactory loss . Am J Rhinol Allergy 24 : 336 – 340 . doi: 10.2500/ajra.2010.24.3498 . 21243089 

  21. 21. Vawter MP , Basaric-Keys J , Li Y , Lester DS , Lebovics RS , Lesch KP , Kulaga H , Freed WJ , Sunderland T , Wolozin B 1996 Human olfactory neuroepithelial cells: tyrosine phosphorylation and process extension are increased by the combination of IL-1beta, IL-6, NGF, and bFGF . Exp Neurol 142 : 179 – 194 . doi: 10.1006/exnr.1996.0189 . 8912909 

  22. 22. van Riel D , Verdijk R , Kuiken T 2015 The olfactory nerve: a shortcut for influenza and other viral diseases into the central nervous system . J Pathol 235 : 277 – 287 . doi: 10.1002/path.4461 . 25294743 

관련 콘텐츠

오픈액세스(OA) 유형

GOLD

오픈액세스 학술지에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로