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Scientific reports, v.7, 2017년, pp.9723 -
Capitanio, Daniele (Department of Biomedical Sciences for Health, University of Milan, Segrate, (MI) Italy) , Fania, Chiara (UO Proteomica Clinica, IRCCS Policlinico San Donato, San Donato Milanese, (MI) Italy) , Torretta, Enrica (Department of Biomedical Sciences for Health, University of Milan, Segrate, (MI) Italy) , Viganò, Agnese (Department of Biomedical Sciences for Health, University of Milan, Segrate, (MI) Italy) , Moriggi, Manuela (CNR-Institute of Bioimaging and Molecular Physiology, Cefalù) , Bravatà, Valentina (, (PA) and Segrate, (MI), Italy) , Caretti, Anna (CNR-Institute of Bioimaging and Molecular Physiology, Cefalù) , Levett, Denny Z. H. (, (PA) and Segrate, (MI), Italy) , Grocott, Michael P. W. (Department of Health Sciences, University of Milan, Milan, Italy) , Samaja, Michele (Centre for Altitude, Space, and Extreme Environment Medicine, University College London (UCL), Institute of Child Health, University College London, London, UK) , Cerretelli, Paolo (Centre for Altitude, Space, and Extreme Environment Medicine, University College London (UCL), Institute of Child Health, University College London, London, UK) , Gelfi, Cecilia (Department of Health Sciences, University of Milan, M)
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In mammals, hypoxic stress management is under the control of the Hypoxia Inducible Factors, whose activity depends on the stabilization of their labile α subunit. In particular, the skeletal muscle appears to be able to react to changes in substrates and O2 delivery by tuning its metabolism. ...
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