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Ultrasensitive, label-free detection of T4 ligase and T4 polynucleotide kinase based on target-triggered hyper-branched rolling circle amplification

Sensors and actuators. B, Chemical, v.260, 2018년, pp.70 - 77  

Jiang, Hongxin (Agro-Environmental Protection Institute, Ministry of Agriculture) ,  Xu, Yaping (Agro-Environmental Protection Institute, Ministry of Agriculture) ,  Dai, Lihong (Agro-Environmental Protection Institute, Ministry of Agriculture) ,  Liu, Xiaowei (Agro-Environmental Protection Institute, Ministry of Agriculture) ,  Kong, Deming (State Key Laboratory of Medicinal Chemical Biology, Nankai University)

Abstract AI-Helper 아이콘AI-Helper

Abstract Ligase and polynucleotide kinase (PNK) play important roles in DNA repair process. In this work, a simple, convenient and ultrasensitive fluorescence biosensor for label-free detection of ligase and PNK was proposed on the basis of target-triggered hyper-branched rolling circle amplificati...

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