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Nutraceuticals and skin appearance: Is there any evidence to support this growing trend?

Nutrition bulletin, v.43 no.1, 2018년, pp.10 - 45  

Spiro, A. (British Nutrition Foundation, London, UK) ,  Lockyer, S. (British Nutrition Foundation, London, UK)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe rise of the nutraceutical market, specifically oral nutrition supplements claiming to improve skin appearance, is striking. This paper aims to examine the published scientific evidence for beneficial effects of nutraceuticals on skin appearance. An overview of skin physiology and intrins...

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참고문헌 (221)

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  53. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1226 7 2009 Scientific opinion on the substantiation of health claims related to vitamin C and protection of DNA, proteins and lipids from oxidative damage (ID 129, 138, 143, 148), antioxidant function of lutein (ID 146), maintenance of vision (ID 141, 142), collagen formation (ID 130, 131, 136, 137, 149), function of the nervous system (ID 133), function of the immune system (ID 134), function of the immune system during and after extreme physical exercise (ID 144), non‐haem iron absorption (ID 132, 147), energy‐yielding metabolism (ID 135), and relief in case of irritation in the upper respiratory tract (ID 1714, 1715) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  54. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1221 7 2009 10.2903/j.efsa.2009.1221 Scientific opinion on the substantiation of health claims related to vitamin A and cell differentiation (ID 14), function of the immune system (ID 14), maintenance of skin and mucous membranes (ID 15, 17), maintenance of vision (ID 16), maintenance of bone (ID 13, 17), maintenance of teeth (ID 13, 17), maintenance of hair (ID 17), maintenance of nails (ID 17), metabolism of iron (ID 206), and protection of DNA, proteins and lipids from oxidative damage (ID 209) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  55. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1231 7 2009 10.2903/j.efsa.2009.1231 Scientific opinion on the substantiation of health claims related to beta carotene and physiological immune responses of the skin in relation to UV radiation (sun exposure) (ID 198, 1463) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  56. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1461 8 2010 Scientific opinion on dietary reference values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol 

  57. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1814 8 2010 Scientific opinion on the substantiation of health claims related to riboflavin (vitamin B2) and contribution to normal energy‐yielding metabolism (ID 29, 35, 36, 42), contribution to normal metabolism of iron (ID 30, 37), maintenance of normal skin and mucous membranes (ID 31, 33), contribution to normal psychological functions (ID 32), maintenance of normal bone (ID 33), maintenance of normal teeth (ID 33), maintenance of normal hair (ID 33), maintenance of normal nails (ID 33), maintenance of normal vision (ID 39), maintenance of normal red blood cells (ID 40), reduction of tiredness and fatigue (ID 41), protection of DNA, proteins and lipids from oxidative damage (ID 207), and maintenance of the normal function of the nervous system (ID 213) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  58. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1754 8 2010 10.2903/j.efsa.2010.1754 Scientific opinion on the substantiation of health claims related to vitamin A (including β‐carotene) and maintenance of normal vision (ID 4239, 4701), maintenance of normal skin and mucous membranes (ID 4660, 4702), and maintenance of normal hair (ID 4660) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  59. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1819 8 2010 Scientific opinion on the substantiation of health claims related to wheat germ oil and maintenance of normal blood pressure (ID 1386), maintenance of normal blood cholesterol concentrations (ID 599, 2618), maintenance of normal (fasting) blood concentrations of triglycerides (ID 2618), protection of the skin from photo‐oxidative (UV‐induced) damage (ID 600), maintenance of normal skin hydration (ID 600, 1390), maintenance of normal bone (ID 1389), contribution to normal neurological function (ID 1387), contribution to normal cognitive function (ID 1394), contribution to normal fertility (ID 1392), relief of menstrual pain (ID 1395), “digestive system” (ID 1388) and protection of cells from premature aging (ID 1393, 2616) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  60. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 1819 8 2010 10.2903/j.efsa.2010.1819 Scientific opinion on the substantiation of health claims related to zinc and maintenance of normal skin (ID 293), DNA synthesis and cell division (ID 293), contribution to normal protein synthesis (ID 293, 4293), maintenance of normal serum testosterone concentrations (ID 301), “normal growth” (ID 303), reduction of tiredness and fatigue (ID 304), contribution to normal carbohydrate metabolism (ID 382), maintenance of normal hair (ID 412), maintenance of normal nails (ID 412) and contribution to normal macronutrient metabolism (ID 2890) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  61. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 175 8 2010 Scientific opinion on the substantiation of health claims related to various food(s)/food constituent(s) and protection of cells from premature ageing (ID 1668, 1917, 2515, 2527, 2530, 2575, 2580, 2591, 2620, 3178, 3179, 3180, 3181, 4329, 4415), antioxidant activity, antioxidant content and antioxidant properties (ID 857, 1306, 2515, 2527, 2530, 2575, 2580, 2591, 2629, 2728, 4327, 4365, 4380, 4390, 4394, 4455, 4464, 4507, 4694, 4705), protection of DNA, proteins and lipids from oxidative damage (ID 1196, 1211, 1216, 1306, 1312, 1440, 1441, 1666, 1668, 1692, 1900, 1914, 1948, 2023, 2158, 2517, 2522, 2527, 2575, 2591, 2620, 2637, 2639, 2663, 2860, 3079, 3276, 3564, 3818, 4324, 4329, 4351, 4397, 4416, 4424, 4507, 4527, 4528, 4542, 4611, 4629, 4659) and bioavailability of anthocyanins in black currants (ID 4220) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  62. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2474 9 2011 10.2903/j.efsa.2011.2474 Guidance on the scientific requirements for health claims related to antioxidants, oxidative damage and cardiovascular health 

  63. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2206 9 2011 Scientific opinion on the substantiation of health claims related to astaxanthin and protection of the skin from UV‐induced damage (ID 1687, 1979), defence against Helicobacter pylori (ID 1686), contribution to normal spermatogenesis (ID 1688), contribution to normal muscle function (ID 1685), and “immune system” (ID 1689, 1919, 1980) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  64. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2021 9 2011 Scientific opinion on the substantiation of health claims related to beta carotene and protection of DNA, proteins and lipids from oxidative damage (ID 19, 197, 1262, 1460), protection of the skin from UV‐induced (including photo‐oxidative) damage (ID 178, 197, 1263, 1461, 1968, 2320) and maintenance of the normal function of the immune system (ID 200, 1462) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  65. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2021 9 2011 Scientific opinion on the substantiation of health claims related to beta carotene and protection of DNA, proteins and lipids from oxidative damage (ID 19, 197, 1262, 1460), protection of the skin from UV‐induced (including photo‐oxidative) damage (ID 178, 197, 1263, 1461, 1968, 2320) and maintenance of the normal function of the immune system (ID 200, 1462) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  66. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2059 9 2011 Scientific opinion on the substantiation of health claims related to gamma linolenic acid (GLA) and maintenance of normal blood LDL cholesterol concentrations (ID 2661, 4452, 4453), maintenance of normal blood pressure (ID 2662), reduction of menstrual discomfort (ID 495, 640, 1773, 1775), contribution to normal cognitive function (ID 1770), maintenance of the barrier function of the skin (ID 499, 591, 639, 676, 1554, 2003, 2065), “function of the cell membrane” (ID 1769), maintenance of normal structure, elasticity and appearance of the skin (ID 2660, 4296), and “anti‐inflammatory properties” (ID 4454) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  67. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2030 9 2011 Scientific opinion on the substantiation of health claims related to lutein and protection of DNA, proteins and lipids from oxidative damage (ID 3427), protection of the skin from UV‐induced (including photo oxidative) damage (ID 1605, 1779) and maintenance of normal vision (ID 1779, 2080) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  68. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2031 9 2011 Scientific opinion on the substantiation of health claims related to lycopene and protection of DNA, proteins and lipids from oxidative damage (ID 1608, 1609, 1611, 1662, 1663(1664), 1899, 1942. 2081, 2082, 2142, 2374), protection of the skin from UV‐induced (including photo‐oxidative) damage (ID 1259, 1607, 1665, 2143, 2262, 2373), contribution to normal cardiac function (ID 1610, 2372), and maintenance of normal vision (ID 1827) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  69. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2259 9 2011 Scientific opinion on the substantiation of health claims related to silicon and protection against aluminium accumulation in the brain (ID 290), “cardiovascular health” (ID 289), forming a protective coat on the mucous membrane of the stomach (ID 345), neutralisation of gastric acid (ID 345), contribution to normal formation of collagen and connective tissue (ID 287, 288, 333, 334, 335, 1405, 1652, 1718, 1719, 1945), maintenance of normal bone (ID 287, 335, 1652, 1718, 1945), maintenance of normal joints (ID 1405, 1652, 1945), maintenance of normal appearance and elasticity of the skin (ID 288, 333), and contribution to normal formation of hair and nails (ID 334, 1652, 1719) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  70. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2264 9 2011 Scientific opinion on the substantiation of health claims related to soy isoflavones and protection of DNA, proteins and lipids from oxidative damage (ID 1286, 4245), maintenance of normal blood LDL cholesterol concentrations (ID 1135, 1704a, 3093a), reduction of vasomotor symptoms associated with menopause (ID 1654, 1704b, 2140, 3093b, 3154, 3590), maintenance of normal skin tonicity (ID 1704a), contribution to normal hair growth (ID 1704a, 4254), “cardiovascular health” (ID 3587), treatment of prostate cancer (ID 3588) and “upper respiratory tract” (ID 3589) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

  71. EFSA Journal EFSA Panel on Dietetic Products Nutrition and Allergies 2231 9 2011 10.2903/j.efsa.2011.2231 Scientific opinion on the substantiation of health claims related to Lactobacillus johnsonii NCC 533 (La1) (CNCM I‐1225) and improving immune defence against pathogenic gastro‐intestinal microorganisms (ID 896), and protection of the skin from UV‐induced damage (ID 900) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 

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