[논문]Effects of Geometrical Uncertainties on Whole Breast Radiotherapy: A Comparison of Four Different Techniques

Nakamura, Naoki; Takahashi, Osamu; Kamo, Minobu; Hatanaka, Shogo; Endo, Haruna; Mizuno, Norifumi; Shikama, Naoto; Ogita, Mami; Sekiguchi, Kenji

doi:10.4048/jbc.2014.17.2.157

Effects of Geometrical Uncertainties on Whole Breast Radiotherapy: A Comparison of Four Different Techniques 원문보기

Journal of breast cancer= 한국유방암학회지, v.17 no.2, 2014년, pp.157 - 160

Nakamura, Naoki (Department of Radiation Oncology, St. Luke's International Hospital, Tokyo, Japan.) , Takahashi, Osamu (Division of General Internal Medicine, Department of Medicine, St. Luke's International Hospital, Tokyo, Japan.) , Kamo, Minobu (Department of Radiology, St. Luke's International Hospital, Tokyo, Japan.) , Hatanaka, Shogo (Department of Radiation Oncology, St. Luke's International Hospital, Tokyo, Japan.) , Endo, Haruna (Department of Radiation Oncology, St. Luke's International Hospital, Tokyo, Japan.) , Mizuno, Norifumi (Department of Radiation Oncology, St. Luke's International Hospital, Tokyo, Japan.) , Shikama, Naoto (Department of Radiation Oncology, Saitama Medical University International Medical Center, Hidaka, Japan.) , Ogita, Mami (Department of Radiation Oncology, St. Luke's International Hospital, Tokyo, Japan.) , Sekiguchi, Kenji (Department of Radiation Oncology, St. Luke's International Hospital, Tokyo, Japan.)

Abstract ▼ AI-Helper

PurposeThe purpose of this study was to quantify the target coverage, homogeneity, and robustness of the dose distributions against geometrical uncertainties associated with four whole breast radiotherapy techniques.MethodsThe study was based on the planning-computed tomography-datasets of 20 patients who underwent whole breast radiotherapy. A total of four treatment plans (wedge, field-in-field [FIF], hybrid intensity-modulated radiotherapy [IMRT], and full IMRT) were created for each patient. The hybrid IMRT plans comprised two opposed tangential open beams plus two IMRT beams. Setup errors were simulated by moving the beam isocenters by 5 mm in the anterior or posterior direction.ResultsWith the original plan, the wedge technique yielded a high volume receiving ≥107% of the prescription dose (V107; 7.5%±4.2%), whereas the other three techniques yielded excellent target coverage and homogeneity. A 5 mm anterior displacement caused a large and significant increase in the V107 (+5.2%±4.1%, p<0.01) with the FIF plan, but not with the hybrid IMRT (+0.4%±1.2%, p=0.11) or full IMRT (+0.7%±1.8%, p=0.10) plan. A 5-mm posterior displacement caused a large decrease in the V95 with the hybrid IMRT (-2.5%±3.7%, p<0.01) and full IMRT (-4.3%±5.1%, p<0.01) plans, but not with the FIF plan (+0.1%±0.7%, p=0.74). The decrease in V95 was significantly smaller with the hybrid IMRT plan than with the full IMRT plan (p<0.01).ConclusionThe FIF, hybrid IMRT, and full IMRT plans offered excellent target coverage and homogeneity. Hybrid IMRT provided better robustness against geometrical uncertainties than full IMRT, whereas FIF provided comparable robustness to that of hybrid IMRT.

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참고문헌 (11)

1 Aref A Thornton D Youssef E He T Tekyi-Mensah S Denton L Dosimetric improvements following 3D planning of tangential breast irradiation Int J Radiat Oncol Biol Phys 2000 48 1569 1574 11121663

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2 Buchholz TA Gurgoze E Bice WS Prestidge BR Dosimetric analysis of intact breast irradiation in off-axis planes Int J Radiat Oncol Biol Phys 1997 39 261 267 9300762

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3 Smith BD Pan IW Shih YC Smith GL Harris JR Punglia R Adoption of intensity-modulated radiation therapy for breast cancer in the United States J Natl Cancer Inst 2011 103 798 809 21525437

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4 Harsolia A Kestin L Grills I Wallace M Jolly S Jones C Intensity-modulated radiotherapy results in significant decrease in clinical toxicities compared with conventional wedge-based breast radiotherapy Int J Radiat Oncol Biol Phys 2007 68 1375 1380 17544598

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5 van Mourik A van Kranen S den Hollander S Sonke JJ van Herk M van Vliet-Vroegindeweij C Effects of setup errors and shape changes on breast radiotherapy Int J Radiat Oncol Biol Phys 2011 79 1557 1564 20933341

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6 Jain P Marchant T Green M Watkins G Davies J McCarthy C Inter-fraction motion and dosimetric consequences during breast intensity-modulated radiotherapy (IMRT) Radiother Oncol 2009 90 93 98 19012980

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7 Fan Y Nath R Intensity modulation under geometrical uncertainty: a deconvolution approach to robust fluence Phys Med Biol 2010 55 4029 4045 20601776

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8 Schwarz M Van der Geer J Van Herk M Lebesque JV Mijnheer BJ Damen EM Impact of geometrical uncertainties on 3D CRT and IMRT dose distributions for lung cancer treatment Int J Radiat Oncol Biol Phys 2006 65 1260 1269 16798418

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9 Bos LJ van der Geer J van Herk M Mijnheer BJ Lebesque JV Damen EM The sensitivity of dose distributions for organ motion and set-up uncertainties in prostate IMRT Radiother Oncol 2005 76 18 26 16024120

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10 de la Torre N Figueroa CT Martinez K Riley S Chapman J A comparative study of surface dose and dose distribution for intact breast following irradiation with field-in-field technique vs. the use of conventional wedges Med Dosim 2004 29 109 114 15191757
11 Nakamura N Hatanaka S Shikama N Akahane K Sekiguchi K Quantification of cold spots caused by geometrical uncertainty in field-in-field techniques for whole breast radiotherapy Jpn J Clin Oncol 2011 41 1127 1131 21835824

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Effects of Geometrical Uncertainties on Whole Breast Radiotherapy: A Comparison of Four Different Techniques 원문보기

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