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NTIS 바로가기Frontiers in pharmacology, v.7, 2016년, pp.273 -
Pallio, Giovanni (Section of Pharmacology, Department of Clinical and Experimental Medicine, Medical School, University of Messina Messina, Italy) , Bitto, Alessandra (Section of Pharmacology, Department of Clinical and Experimental Medicine, Medical School, University of Messina Messina, Italy) , Pizzino, Gabriele (Section of Pharmacology, Department of Clinical and Experimental Medicine, Medical School, University of Messina Messina, Italy) , Galfo, Federica (Section of Pharmacology, Department of Clinical and Experimental Medicine, Medical School, University of Messina Messina, Italy) , Irrera, Natasha (Section of Pharmacology, Department of Clinical and Experimental Medicine, Medical School, University of Messina Messina, Italy) , Squadrito, Francesco (Section of Pharmacology, Department of Clinical and Experimental Medicine, Medical School, University of Messina Messina, Italy) , Squadrito, Giovanni (Department) , Pallio, Socrate , Anastasi, Giuseppe P. , Cutroneo, Giuseppina , Macrì, Antonio , Altavilla, Domenica
Activation of the adenosine receptor pathway has been demonstrated to be effective in improving tissue remodeling and blunting the inflammatory response. Active colitis is characterized by an intense inflammatory reaction resulting in extensive tissue damage. Symptomatic improvement requires both co...
Aherne C. M. Saeedi B. Collins C. B. Masterson J. C. McNamee E. N. Perrenoud L. ( 2015 ). Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal Immunol. 8 1324 – 1338 . 25850656
Alam M. S. Costales M. G. Cavanaugh C. Williams K. ( 2015 ). Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogencolonization. Biomolecules 5 775 – 792 . 10.3390/biom5020775 25950510
Altavilla D. Squadrito F. Polito F. Irrera N. Calò M. Lo Cascio P. ( 2011 ). Activation of adenosine A2A receptors restores the altered cell-cycle machinery during impaired wound healing in genetically diabetic mice. Surgery 149 253 – 261 . 10.1016/j.surg.2010.04.024 20570301
Antonioli L. Csóka B. Fornai M. Colucci R. Kókai E. Blandizzi C. ( 2014 ). Adenosine and inflammation: what’s new on the horizon? Drug Discov. Today 19 1051 – 1068 . 10.1016/j.drudis.2014.02.010 24607729
Antonioli L. Fornai M. Colucci R. Awwad O. Ghisu N. Tuccori M. ( 2010 ). The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors. J. Pharmacol. Exp. Ther. 335 434 – 442 . 10.1124/jpet.110.171223 20668053
Antonioli L. Fornai M. Colucci R. Awwad O. Ghisu N. Tuccori M. ( 2011 ). Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis. Eur. J. Pharmacol. 15 639 – 649 . 10.1016/j.ejphar.2010.10.041
Arolfo M. P. Yao L. Gordon A. S. Diamond I. Janak P. H. ( 2004 ). Ethanol operant self-administration in rats is regulated by adenosine A2 receptors. Alcohol. Clin. Exp. Res. 28 1308 – 1316 . 15365300
Balasubramanyan S. Sharma S. S. ( 2008 ). Protective effect of adenosine in diabetic neuropathic pain is mediated through adenosine A1-receptors. Indian J. Physiol. Pharmacol. 52 233 – 242 . 19552053
Barrett K. E. Huott P. A. Shah S. S. Dharmsathaphorn K. Wasserman S. I. ( 1989 ). Differing effects of apical and basolateral adenosine on colonic epithelial cell line T84. Am. J. Physiol. 256 197 – 203 .
Baumgart D. C. Sandborn W. J. ( 2007 ). Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 369 1641 – 1657 . 10.1016/S0140-6736(07)60751-X 17499606
Bitto A. Oteri G. Pisano M. Polito F. Irrera N. Minutoli L. ( 2013 ). Adenosine receptor stimulation by polynucleotides (PDRN) reduces inflammation in experimental periodontitis. J. Clin. Periodontol. 40 26 – 32 . 10.1111/jcpe.12010 23033941
Bitto A. Polito F. Irrera N. D’Ascola A. Avenoso A. Nastasi G. ( 2011 ). Polydeoxyribonucleotide reduces cytokine production and the severity of collagen-induced arthritis by stimulation of adenosine A2A receptor. Arthritis Rheum. 63 3364 – 3371 . 10.1002/art.30538 21769841
Burger D. Travis S. ( 2011 ). Conventional medical management of inflammatory bowel disease. Gastroenterology 140 1827 – 1837 . 10.1053/j.gastro.2011.02.045 21530749
Cavalcante I. C. Castro M. V. Barreto A. R. Sullivan G. W. Vale M. Almeida P. R. ( 2006 ). Effect of novel A2A adenosine receptor agonist ATL 313 on clostridium difficile toxin a-induced murine ileal enteritis. Infect. Immun. 74 2606 – 2612 . 10.1128/IAI.74.5.2606-2612.2006 16622196
Cronstein B. N. Kramer S. B. Weissmann G. Hirschhorn R. ( 1983 ). Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J. Exp. Med. 158 1160 – 1177 . 10.1084/jem.158.4.1160 6311934
Cronstein B. N. Rosenstein E. D. Kramer S. B. Weissmann G. Hirschhorn R. ( 1985 ). Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils. J. Immunol. 135 1366 – 1371 . 2989364
Desrosiers M. D. Cembrola K. M. Fakir M. J. Stephens L. A. Jama F. M. Shameli A. ( 2007 ). Adenosine deamination sustains dendritic cell activation in inflammation. J. Immunol. 179 1884 – 1892 . 17641055
Fornai M. Antonioli L. Colucci R. Ghisu N. Buccianti P. Marioni A. ( 2009 ). A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon. Neurogastroenterol. Motil. 21 451 – 466 . 10.1111/j.1365-2982.2008.01213.x 19019012
Fortin A. Harbour D. Fernandes M. Borgeat P. Bourgoin S. ( 2006 ). Differential expression of adenosine receptors in human neutrophils: up-regulation by specific Th1 cytokines and lipopolysaccharide. J. Leukoc. Biol. 79 574 – 585 . 10.1189/jlb.0505249 16387843
Galeano M. Bitto A. Altavilla D. Minutoli L. Polito F. Calò M. ( 2008 ). Polydeoxyribonucleotide stimulates angiogenesis and wound healing in the genetically diabetic mouse. Wound Repair Regen. 16 208 – 217 . 10.1111/j.1524-475X.2008.00361.x 18318806
Grisham M. B. ( 1994 ). Oxidants and free radicals in inflammatory bowel disease. Lancet 344 859 – 861 . 10.1016/S0140-6736(94)92831-2 7916405
Haskò G. Kuhel D. G. Chen J. F. Schwarzschild M. A. Deitch E. A. Mablev J. G. ( 2000 ). Adenosine inhibits IL-12 and TNF-α production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J. 14 2065 – 2074 . 10.1096/fj.99-0508com 11023991
Haskó G. Linden J. Cronstein B. Pacher P. ( 2008 ). Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat. Rev. Drug Discov. 7 759 – 770 . 10.1038/nrd2638 18758473
Kreckler L. M. Wan T. C. Ge Z. D. Auchampach J. A. ( 2006 ). Adenosine inhibits tumor necrosis factor-α release from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor. J. Pharmacol. Exp. Ther. 317 172 – 180 . 10.1124/jpet.105.096016 16339914
Lam R. S. Nahirney D. Duszyk M. ( 2009 ). Cholesterol-dependent regulation of adenosine A(2A) receptor-mediated anion secretion in colon epithelial cells. Exp. Cell Res. 15 3028 – 3035 . 10.1016/j.yexcr.2009.06.005
Li Y. Figler R. A. Kolling G. Bracken T. C. Rieger J. Stevenson R. W. ( 2012 ). Adenosine A2A receptor activation reduces recurrence and mortality from Clostridium difficile infection in mice following vancomycin treatment. BMC Infect. Dis. 10 : 342 . 10.1186/1471-2334-12-342
Mayne M. Fotheringham J. Yan H. J. Power C. Del Bigio M. R. Peeling J. ( 2001 ). Adenosine A2A receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage. Ann. Neurol. 49 727 – 735 . 10.1002/ana.1010 11409424
McGrath J. Drummond G. Kilkenny C. Wainwright C. ( 2010 ). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br. J. Pharmacol. 160 1573 – 1576 . 10.1111/j.1476-5381.2010.00873.x 20649560
Mullane K. M. Kraemer R. Smith B. ( 1985 ). Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Methods 14 157 – 167 . 10.1016/0160-5402(85)90029-4 2997548
Munzar P. Justinova Z. Kutkat S. W. Ferré S. Goldberg S. R. ( 2002 ). Adenosinergic modulation of the discriminative-stimulus effects of methamphetamine in rats. Psychopharmacology (Berl). 161 348 – 355 . 10.1007/s00213-002-1075-5 12073161
Nunes T. Bernardazzi C. De Souza H. S. ( 2014 ). Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium. Biomed. Res. Int. 2014 : 218493 . 10.1155/2014/218493
Odashima M. Bamias G. Rivera-Nieves J. Linden J. Nast C. C. Moskaluk C. A. ( 2005 ). Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology 129 26 – 33 . 10.1053/j.gastro.2005.05.032 16012931
Ohkawa H. Ohishi N. Yagi K. ( 1979 ). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95 351 – 358 . 10.1016/0003-2697(79)90738-3 36810
Onishi R. Ohnishi S. Higashi R. Watari M. Yamahara K. Okubo N. ( 2015 ). Human amnion-derived mesenchymal stem cell transplantation ameliorates dextran sulfate sodium-induced severe colitis in rats. Cell Transplant. 24 2601 – 2614 . 10.3727/096368915X687570 25812083
Pavlick K. P. Laroux F. S. Fuseler J. Wolf R. E. Gray L. Hoffman J. ( 2002 ). Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease. Free Radic. Biol. Med. 33 311 – 322 . 10.1016/S0891-5849(02)00853-5 12126753
Podolsky D. K. ( 2002 ). Inflammatory bowel disease. N. Engl. J. Med. 347 417 – 429 . 10.1056/NEJMra020831 12167685
Polito F. Bitto A. Galeano M. Irrera N. Marini H. Calò M. ( 2012 ). Polydeoxyribonucleotide restores blood flow in an experimental model of ischemic skin flaps. J. Vasc. Surg. 55 479 – 488 . 10.1016/j.jvs.2011.07.083 22051873
Rachmilewitz D. Stamler J. S. Karmeli F. Mullins M. E. Singel D. J. Loscalzo J. ( 1993 ). Peroxynitrite induced rat colitis a new model of colonic inflammation. Gastroenterology 105 1681 – 1688 . 10.1016/0016-5085(93)91063-N 8253344
Rahimian R. Fakhfouri G. Daneshmand A. Mohammadi H. Bahremand A. Rasouli M. R. ( 2010 ). Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats. Eur. J. Pharmacol. 649 376 – 381 . 10.1016/j.ejphar.2010.09.044 20868668
Shaulian E. Karin M. ( 2012 ). AP-1 as a regulator of cell life and death. Nat. Cell Biol. 4 131 – 136 . 10.1038/ncb0502-e131
Squadrito F. Bitto A. Altavilla D. Arcoraci V. De Caridi G. De Feo M. E. ( 2014 ). The effect of PDRN, an adenosine receptor A2A agonist, on the healing of chronic diabetic foot ulcers: results of a clinical trial. J. Clin. Endocrinol. Metab. 99 E746 – E753 . 10.1210/jc.2013-3569 24483158
Strober W. Fuss I. J. ( 2011 ). Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology 140 1756 – 1767 . 10.1053/j.gastro.2011.02.016 21530742
Sullivan G. W. Lee D. D. Ross W. G. Di Vietro J. A. Lappas C. M. Lawrence M. B. ( 2004 ). Activation of A2A adenosine receptors inhibits expression of α4/β1 integrin (verylate antigen-4) on stimulated human neutrophils. J. Leukoc. Biol. 75 127 – 134 . 10.1189/jlb.0603300 14525968
Thorsell A. Johnson J. Heilig M. ( 2007 ). Effect of the adenosine A2a receptor antagonist 3,7-dimethyl-propargylxanthine on anxiety-like and depression-like behavior and alcohol consumption in Wistar Rats. Alcohol. Clin. Exp. Res. 31 1302 – 1327 . 10.1111/j.1530-0277.2007.00425.x 17550371
Wallace J. L. Keenan C. M. Gale D. Shoupe T. S. ( 1992 ). Exacerbation of experimental colitis by nonsteroidal anti-inflammatory drugs is not related to elevated leukotriene B4 synthesis. Gastroenterology 102 18 – 27 . 10.1016/0016-5085(92)91779-4 1309357
Wang M. L. Yu G. Yi S. P. Zhang F. Y. Wang Z. T. Huang B. ( 2015 ). Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis , and possible involvement of the adenosine system. Sci. Rep. 5 16107 – 16118 . 10.1038/srep16107 26527075
Yao L. McFarland K. Fan P. Jiang Z. Ueda T. Diamond I. ( 2006 ). Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats. Proc. Natl. Acad Sci. U.S.A. 16 7877 – 7882 . 10.1073/pnas.0602661103
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