다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Frontiers in microbiology, v.7, 2016년, pp.925 -
O'Callaghan, Amy , van Sinderen, Douwe
AI-Helper
Members of the genus Bifidobacterium are among the first microbes to colonize the human gastrointestinal tract and are believed to exert positive health benefits on their host. Due to their purported health-promoting properties, bifidobacteria have been incorporated into many functional foods as act...
Amaretti A. Bernardi T. Leonardi A. Raimondi S. Zanoni S. Rossi M. ( 2013 ). Fermentation of xylo-oligosaccharides by Bifidobacterium adolescentis DSMZ 18350: kinetics, metabolism, and beta-xylosidase activities . Appl. Microbiol. Biotechnol. 97 , 3109 – 3117 . 10.1007/s00253-012-4509-y 23099913
Arigoni F. Delley M. ( 2013 ). Genetic Remodeling in Bifidobacterium . Vevey : Google Patents .
Backhed F. Ley R. E. Sonnenburg J. L. Peterson D. A. Gordon J. I. ( 2005 ). Host-bacterial mutualism in the human intestine . Science, 307 , 1915 – 1920 . 10.1126/science.1104816 15790844
Bae E.-A. Han M. J. Song M.-J. Kim D.-H. ( 2002 ). Purification of Rotavirus Infection-Inhibitory Protein from Bifidobacterium Breve K-110 . Seoul : COREE, REPUBLIQUE DE, Korean Society for Applied Microbiology .
Barrangou R. Briczinski E. P. Traeger L. L. Loquasto J. R. Richards M. Horvath P. . ( 2009 ). Comparison of the complete genome sequences of Bifidobacterium animalis subsp. lactis DSM 10140 and Bl-04 . J. Bacteriol. 191 , 4144 – 4151 . 10.1128/JB.00155-09 19376856
Bernet M. F. Brassart D. Neeser J. R. Servin A. L. ( 1994 ). Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria . Gut, 35 , 483 – 489 . 10.1136/gut.35.4.483 8174985
Bindels L. B. Delzenne N. M. Cani P. D. Walter J. ( 2015 ). Towards a more comprehensive concept for prebiotics . Nat. Rev. Gastroenterol. Hepatol. 12 , 303 – 310 . 10.1038/nrgastro.2015.47 25824997
Biswas I. Gruss A. Ehrlich S. D. Maguin E. ( 1993 ). High-efficiency gene inactivation and replacement system for gram-positive bacteria . J. Bacteriol. 175 , 3628 – 3635 . 8501066
Bosscher D. Van Loo J. Franck A. ( 2006 ). Inulin and oligofructose as prebiotics in the prevention of intestinal infections and diseases . Nutr. Res. Rev. 19 , 216 – 226 . 10.1017/S0954422407249686 19079887
Bottacini F. O'Connell Motherway M. Casey E. McDonnell B. Mahony J. Ventura M. . ( 2015 ). Discovery of a conjugative megaplasmid in bifidobacterium breve . Appl. Environ. Microbiol. 81 , 166 – 176 . 10.1128/AEM.02871-14 25326305
Broekaert W. F. Courtin C. M. Verbeke K. Van De Wiele T. Verstraete W. Delcour J. A. ( 2011 ). Prebiotic and other health-related effects of cereal-derived arabinoxylans, arabinoxylan-oligosaccharides, and xylooligosaccharides . Crit. Rev. Food Sci. Nutr. 51 , 178 – 194 . 10.1080/10408390903044768 21328111
Chaplin A. V. Efimov B. A. Smeianov V. V. Kafarskaia L. I. Pikina A. P. Shkoporov A. N. ( 2015 ). Intraspecies genomic diversity and long-term persistence of Bifidobacterium longum . PLoS ONE 10 : e0135658 . 10.1371/journal.pone.0135658 26275230
Chen X. Dego O. K. Almeida R. A. Fuller T. E. Luther D. A. Oliver S. P. ( 2011 ). Deletion of sua gene reduces the ability of Streptococcus uberis to adhere to and internalize into bovine mammary epithelial cells . Vet. Microbiol. 147 , 426 – 434 . 10.1016/j.vetmic.2010.07.006 20708860
Chenoll E. Rivero M. Codoñer F. M. Martinez-Blanch J. F. Ramón D. Genovés S. . ( 2015 ). Complete genome sequence of Bifidobacterium longum subsp. infantis Strain CECT 7210, a probiotic strain active against rotavirus infections . Genome Announcements 3 : e00105-15 . 10.1128/genomea.00105-15 25838473
Christiaen S. E. O'Connell Motherway M. Bottacini F. Lanigan N. Casey P. G. Huys G. . ( 2014 ). Autoinducer-2 plays a crucial role in gut colonization and probiotic functionality of Bifidobacterium breve UCC2003 . PLoS ONE 9 : e98111 . 10.1371/journal.pone.0098111 24871429
Corrêa N. B. O. Péret Filho L. A. Penna F. J. Lima F. M. L. S. Nicoli J. R. ( 2005 ). A randomized formula controlled trial of bifidobacterium lactis and streptococcus thermophilus for prevention of antibiotic-associated diarrhea in infants . J. Clin. Gastroenterol. 39 , 385 – 389 . 10.1097/01.mcg.0000159217.47419.5b 15815206
Crittenden R. Karppinen S. Ojanen S. Tenkanen M. Fagerström R. Mättö J. ( 2002 ). In vitro fermentation of cereal dietary fibre carbohydrates by probiotic and intestinal bacteria . J. Sci. Food Agric. 82 , 781 – 789 . 10.1002/jsfa.1095
Cronin M. Ventura M. Fitzgerald G. F. Van Sinderen D. ( 2011 ). Progress in genomics, metabolism and biotechnology of bifidobacteria . Int. J. Food Microbiol. 149 , 4 – 18 . 10.1016/j.ijfoodmicro.2011.01.019 21320731
Davidson A. L. Dassa E. Orelle C. Chen J. ( 2008 ). Structure, function, and evolution of bacterial ATP-binding cassette systems . Microbiol Mol. Biol. Rev. 72 , 317 – 364 . 10.1128/MMBR.00031-07 18535149
Davis L. M. Martinez I. Walter J. Hutkins R. ( 2010 ). A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults . Int. J. Food Microbiol. 144 , 285 – 292 . 10.1016/j.ijfoodmicro.2010.10.007 21059476
Degnan B. A. Macfarlane G. T. ( 1993 ). Transport and metabolism of glucose and arabinose in Bifidobacterium breve . Arch. Microbiol. 160 , 144 – 151 . 10.1007/BF00288717 8216508
De La Cochetiere M. F. Piloquet H. Des Robert C. Darmaun D. Galmiche J. P. Roze J. C. ( 2004 ). Early intestinal bacterial colonization and necrotizing enterocolitis in premature infants: the putative role of Clostridium . Pediatr. Res. 56 , 366 – 370 . 10.1203/01.PDR.0000134251.45878.D5 15201403
De Vries W. Stouthamer A. H. ( 1967 ). Pathway of glucose fermentation in relation to the taxonomy of bifidobacteria . J. Bacteriol. 93 , 574 – 576 . 6020562
De Vuyst L. Leroy F. ( 2011 ). Cross-feeding between bifidobacteria and butyrate-producing colon bacteria explains bifdobacterial competitiveness, butyrate production, and gas production . Int. J. Food Microbiol. 149 , 73 – 80 . 10.1016/j.ijfoodmicro.2011.03.003 21450362
De Vuyst L. Moens F. Selak M. Riviere A. Leroy F. ( 2014 ). Summer Meeting 2013: growth and physiology of bifidobacteria . J. Appl. Microbiol. 116 , 477 – 491 . 10.1111/jam.12415 24314205
Dominguez W. O'Sullivan D. J. ( 2013 ). Developing an efficient and reproducible conjugation-based gene transfer system for bifidobacteria . Microbiology 159 , 328 – 338 . 10.1099/mic.0.061408-0 23197173
Duffy L. C. Zielezny M. A. Riepenhoff-Talty M. Dryja D. Sayahtaheri-Altaie S. Griffiths E. . ( 1994a ). Reduction of virus shedding by B. bifidum in experimentally induced MRV infection. Statistical application for ELISA . Dig. Dis. Sci. 39 , 2334 – 2340 . 10.1007/BF02087647 7956600
Duffy L. C. Zielezny M. A. Riepenhoff-Talty M. Dryja D. Sayahtaheri-Altaie S. Griffiths E. . ( 1994b ). Effectiveness of Bifidobacterium bifidum in mediating the clinical course of murine rotavirus diarrhea . Pediatr. Res. 35 , 690 – 695 . 10.1203/00006450-199406000-00014 7936820
Duranti S. Milani C. Lugli G. A. Turroni F. Mancabelli L. Sanchez B. . ( 2015 ). Insights from genomes of representatives of the human gut commensal Bifidobacterium bifidum . Environ. Microbiol. 17 , 2515 – 2531 . 10.1111/1462-2920.12743 25523018
Duranti S. Turroni F. Lugli G. A. Milani C. Viappiani A. Mangifesta M. . ( 2014 ). Genomic characterization and transcriptional studies of the starch-utilizing strain bifidobacterium adolescentis 22L . Appl. Environ. Microbiol. 80 , 6080 – 6090 . 10.1128/AEM.01993-14 25063659
Egan M. Motherway M. M. Kilcoyne M. Kane M. Joshi L. Ventura M. . ( 2014a ). Cross-feeding by Bifidobacterium breve UCC2003 during co-cultivation with Bifidobacterium bifidum PRL2010 in a mucin-based medium . BMC Microbiol. 14 : 282 . 10.1186/s12866-014-0282-7 25420416
Egan M. O'Connell Motherway M. Van Sinderen D. ( 2015 ). A GntR-type transcriptional repressor controls sialic acid utilization in Bifidobacterium breve UCC2003 . FEMS Microbiol. Lett. 362 , 1 – 9 . 10.1093/femsle/fnu056 25688064
Egan M. O'Connell Motherway M. Ventura M. Van Sinderen D. ( 2014b ). Metabolism of sialic acid by Bifidobacterium breve UCC2003 . Appl. Environ. Microbiol. 80 , 4414 – 4426 . 10.1128/AEM.01114-14 24814790
El Kaoutari A. Armougom F. Gordon J. I. Raoult D. Henrissat B. ( 2013 ). The abundance and variety of carbohydrate-active enzymes in the human gut microbiota . Nat. Rev. Microbiol. 11 , 497 – 504 . 10.1038/nrmicro3050 23748339
Falony G. Lazidou K. Verschaeren A. Weckx S. Maes D. De Vuyst L. ( 2009 ). In vitro kinetic analysis of fermentation of prebiotic inulin-type fructans by Bifidobacterium species reveals four different phenotypes . Appl. Environ. Microbiol. 75 , 454 – 461 . 10.1128/AEM.01488-08 19011052
Fanaro S. Chierici R. Guerrini P. Vigi V. ( 2003 ). Intestinal microflora in early infancy: composition and development . Acta Paediatr Suppl. 91 , 48 – 55 . 10.1111/j.1651-2227.2003.tb00646.x 14599042
FAO/WHO ( 2001 ). Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria . Cordoba: FAO/WHO.
Favier C. F. Vaughan E. E. De Vos W. M. Akkermans A. D. ( 2002 ). Molecular monitoring of succession of bacterial communities in human neonates . Appl. Environ. Microbiol. 68 , 219 – 226 . 10.1128/AEM.68.1.219-226.2002 11772630
Fouhy F. O'Connell Motherway M. Fitzgerald G. F. Ross R. P. Stanton C. Van Sinderen D. . ( 2013 ). In Silico assigned resistance genes confer Bifidobacterium with partial resistance to aminoglycosides but not to Ί-lactams . PLoS ONE 8 : e82653 . 10.1371/journal.pone.0082653 24324818
Fuchs T. M. Klumpp J. Przybilla K. ( 2006 ). Insertion-duplication mutagenesis of Salmonella enterica and related species using a novel thermosensitive vector . Plasmid 55 , 39 – 49 . 10.1016/j.plasmid.2005.06.003 16125236
Fukiya S. Hirayama Y. Sakanaka M. Kano Y. Yokota A. ( 2012 ). Technological Advances in Bifidobacterial molecular genetics: application to functional genomics and medical treatments . Biosci. Microbiota Food Health 31 , 15 – 25 . 10.12938/bmfh.31.15 24936345
Fukuda S. Toh H. Hase K. Oshima K. Nakanishi Y. Yoshimura K. . ( 2011 ). Bifidobacteria can protect from enteropathogenic infection through production of acetate . Nature 469 , 543 – 547 . 10.1038/nature09646 21270894
Ganong W. ( 2005 ). Ganong's Review of Medical Physiology, 24th Edn, Europe , McGraw-Hill Education .
Gibson G. R. Roberfroid M. B. ( 1995 ). Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics . J. Nutr. 125 , 1401 – 1412 . 7782892
Gionchetti P. Rizzello F. Venturi A. Campieri M. ( 2000 ). Probiotics in infective diarrhoea and inflammatory bowel diseases . J. Gastroenterol. Hepatol. 15 , 489 – 493 . 10.1046/j.1440-1746.2000.02162.x 10847433
Grootaert C. Delcour J. A. Courtin C. M. Broekaert W. F. Verstraete W. Van De Wiele T. ( 2007 ). Microbial metabolism and prebiotic potency of arabinoxylan oligosaccharides in the human intestine . Trends Food Sci. Technol. 18 , 64 – 71 . 10.1016/j.tifs.2006.08.004
Guarner F. Malagelada J. R. ( 2003 ). Gut flora in health and disease . Lancet 361 , 512 – 519 . 10.1016/S0140-6736(03)12489-0 12583961
Gueimonde M. Margolles A. G. De Los Reyes-Gavilán C. Salminen S. ( 2007 ). Competitive exclusion of enteropathogens from human intestinal mucus by Bifidobacterium strains with acquired resistance to bile — A preliminary study . Int. J. Food Microbiol. 113 , 228 – 232 . 10.1016/j.ijfoodmicro.2006.05.017 16842877
Guyonnet D. Chassany O. Ducrotte P. Picard C. Mouret M. Mercier C. H. . ( 2007 ). Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial . Aliment. Pharmacol. Ther. 26 , 475 – 486 . 10.1111/j.1365-2036.2007.03362.x 17635382
Hamilton C. M. Aldea M. Washburn B. K. Babitzke P. Kushner S. R. ( 1989 ). New method for generating deletions and gene replacements in Escherichia coli . J. Bacteriol. 171 , 4617 – 4622 . 2548993
Harmsen H. J. Wildeboer-Veloo A. C. Raangs G. C. Wagendorp A. A. Klijn N. Bindels J. G. . ( 2000 ). Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods . J. Pediatr. Gastroenterol. Nutr. 30 , 61 – 67 . 10.1097/00005176-200001000-00019 10630441
Hijova E. Chmelarova A. Bomba A. Zitnan R. ( 2009 ). Prebiotic foodstuffs and their health benefits in experiment . Bratisl. Lek. Listy 110 , 523 – 525 . 19827333
Hill C. Guarner F. Reid G. Gibson G. R. Merenstein D. J. Pot B. . ( 2014 ). Expert consensus document: the International Scientific Association for probiotics and prebiotics consensus statement on the scope and appropriate use of the term probiotic . Nat. Rev. Gastroenterol. Hepatol. 11 , 506 – 514 . 10.1038/nrgastro.2014.66 24912386
Hirayama Y. Sakanaka M. Fukuma H. Murayama H. Kano Y. Fukiya S. . ( 2012 ). Development of a double-crossover markerless gene deletion system in Bifidobacterium longum: functional analysis of the α-galactosidase gene for raffinose assimilation . Appl. Environ. Microbiol. 78 , 4984 – 4994 . 10.1128/AEM.00588-12 22582061
Hooper L. V. Midtvedt T. Gordon J. I. ( 2002 ). How host-microbial interactions shape the nutrient environment of the mammalian intestine . Annu. Rev. Nutr. 22 , 283 – 307 . 10.1146/annurev.nutr.22.011602.092259 12055347
Hooper L. V. Xu J. Falk P. G. Midtvedt T. Gordon J. I. ( 1999 ). A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem . Proc. Natl. Acad. Sci. U.S.A. 96 , 9833 – 9838 . 10.1073/pnas.96.17.9833 10449780
Hopkins M. Sharp R. Macfarlane G. ( 2001 ). Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles . Gut 48 , 198 – 205 . 10.1136/gut.48.2.198 11156640
Hughes S. A. Shewry P. R. Li L. Gibson G. R. Sanz M. L. Rastall R. A. ( 2007 ). In Vitro Fermentation by Human Fecal Microflora of Wheat Arabinoxylans . J. Agric. Food Chem. 55 , 4589 – 4595 . 10.1021/jf070293g 17488118
Isaacs F. J. Carr P. A. Wang H. H. Lajoie M. J. Sterling B. Kraal L. . ( 2011 ). Precise manipulation of chromosomes in vivo enables genome-wide codon replacement . Science 333 , 348 – 353 . 10.1126/science.1205822 21764749
Ishikawa H. Matsumoto S. Ohashi Y. Imaoka A. Setoyama H. Umesaki Y. . ( 2011 ). Beneficial effects of probiotic bifidobacterium and galacto-oligosaccharide in patients with ulcerative colitis: a randomized controlled study . Digestion 84 , 128 – 133 . 10.1159/000322977 21525768
Islek A. Sayar E. Yilmaz A. Baysan B. O. Mutlu D. Artan R. ( 2014 ). The role of Bifidobacterium lactis B94 plus inulin in the treatment of acute infectious diarrhea in children . Turk. J. Gastroenterol. 25 , 628 – 633 . 10.5152/tjg.2014.14022 25599772
Jaskari J. Kontula P. Siitonen A. Jousimies-Somer H. Mattila-Sandholm T. Poutanen K. ( 1998 ). Oat beta-glucan and xylan hydrolysates as selective substrates for Bifidobacterium and Lactobacillus strains . Appl. Microbiol. Biotechnol. 49 , 175 – 181 . 10.1007/s002530051155 9534257
Jojima T. Omumasaba C. A. Inui M. Yukawa H. ( 2010 ). Sugar transporters in efficient utilization of mixed sugar substrates: current knowledge and outlook . Appl. Microbiol. Biotechnol. 85 , 471 – 480 . 10.1007/s00253-009-2292-1 19838697
Judson N. Mekalanos J. J. ( 2000 ). Transposon-based approaches to identify essential bacterial genes . Trends Microbiol. 8 , 521 – 526 . 10.1016/S0966-842X(00)01865-5 11121763
Ju-Hoon L. O'Sullivan D. J. ( 2010 ). Genomic Insights into Bifidobacteria . Microbiology and Molecular Biology Reviews, 74 , 38 . 10.1128/MMBR.00004-10 20805404
Kapiki A. Costalos C. Oikonomidou C. Triantafyllidou A. Loukatou E. Pertrohilou V. ( 2007 ). The effect of a fructo-oligosaccharide supplemented formula on gut flora of preterm infants . Early Hum. Dev. 83 , 335 – 339 . 10.1016/j.earlhumdev.2006.07.003 16978805
Klappenbach J. A. Dunbar J. M. Schmidt T. M. ( 2000 ). rRNA operon copy number reflects ecological strategies of bacteria . Appl. Environ. Microbiol. 66 , 1328 – 1333 . 10.1128/AEM.66.4.1328-1333.2000 10742207
Kleessen B. Sykura B. Zunft H. J. Blaut M. ( 1997 ). Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons . Am. J. Clin. Nutr. 65 , 1397 – 1402 . 9129468
Klijn A. Mercenier A. Arigoni F. ( 2005 ). Lessons from the genomes of Bifidobacteria . FEMS Microbiol. Rev. 29 , 491 – 509 . 10.1016/j.fmrre.2005.04.010 15939502
Kolida S. Tuohy K. Gibson G. R. ( 2002 ). Prebiotic effects of inulin and oligofructose . Br. J. Nutr. 87 ( Suppl. 2 ), S193 – S197 . 10.1079/BJN/2002537 12088518
Korakli M. Ganzle M. G. Vogel R. F. ( 2002 ). Metabolism by bifidobacteria and lactic acid bacteria of polysaccharides from wheat and rye, and exopolysaccharides produced by Lactobacillus sanfranciscensis . J. Appl. Microbiol. 92 , 958 – 965 . 10.1046/j.1365-2672.2002.01607.x 11972702
Kumemura M. Hashimoto F. Fujii C. Matsuo K. Kimura H. Miyazoe R. ( 1992 ). Effects of administration of 4g-beta-d-galactosylsucrose on fecal microflora, putrefactive products, short-chain fatty-acids, weight, moisture and ph, and subjective sensation of defecation in the elderly with constipation . J. Clin. Biochem. Nutr. 13 , 199 – 210 . 10.3164/jcbn.13.199
Lagaert S. Pollet A. Delcour J. A. Lavigne R. Courtin C. M. Volckaert G. ( 2010 ). Substrate specificity of three recombinant alpha-L-arabinofuranosidases from Bifidobacterium adolescentis and their divergent action on arabinoxylan and arabinoxylan oligosaccharides . Biochem. Biophys. Res. Commun. 402 , 644 – 650 . 10.1016/j.bbrc.2010.10.075 20971079
Lagaert S. Pollet A. Delcour J. A. Lavigne R. Courtin C. M. Volckaert G. ( 2011 ). Characterization of two beta-xylosidases from Bifidobacterium adolescentis and their contribution to the hydrolysis of prebiotic xylooligosaccharides . Appl. Microbiol. Biotechnol. 92 , 1179 – 1185 . 10.1007/s00253-011-3396-y 21691791
Lagaert S. Van Campenhout S. Pollet A. Bourgois T. M. Delcour J. A. Courtin C. M. . ( 2007 ). Recombinant expression and characterization of a reducing-end xylose-releasing exo-oligoxylanase from Bifidobacterium adolescentis . Appl. Environ. Microbiol. 73 , 5374 – 5377 . 10.1128/AEM.00722-07 17586675
Laureys D. Cnockaert M. De Vuyst L. Vandamme P. ( 2016 ). Bifidobacterium aquikefiri sp. nov., isolated from water kefir . Int. J. Syst. Evol. Microbiol. 66 , 1281 – 1286 . 10.1099/ijsem.0.000877
Leahy S. C. Higgins D. G. Fitzgerald G. F. Van Sinderen D. ( 2005 ). Getting better with bifidobacteria . J. Appl. Microbiol. 98 , 1303 – 1315 . 10.1111/j.1365-2672.2005.02600.x 15916644
Lederberg J. Tatum E. L. ( 1946 ). Gene recombination in Escherichia coli . Nature 158 , 558 . 10.1038/158558a0 21001945
Lee J. H. Hyun Y. J. Kim D. H. ( 2011 ). Cloning and characterization of alpha-L-arabinofuranosidase and bifunctional alpha-L-arabinopyranosidase/beta-D-galactopyranosidase from Bifidobacterium longum H-1 . J. Appl. Microbiol. 111 , 1097 – 1107 . 10.1111/j.1365-2672.2011.05128.x 21851513
Lee J. H. Karamychev V. N. Kozyavkin S. A. Mills D. Pavlov A. R. Pavlova N. V. . ( 2008 ). Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth . BMC Genomics 9 : 247 . 10.1186/1471-2164-9-247 18505588
Le Leu R. K. Hu Y. Brown I. L. Woodman R. J. Young G. P. ( 2010 ). Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats . Carcinogenesis 31 , 246 – 251 . 10.1093/carcin/bgp197 19696163
Lombard V. Golaconda Ramulu H. Drula E. Coutinho P. M. Henrissat B. ( 2014 ). The carbohydrate-active enzymes database (CAZy) in (2013) . Nucleic Acids Res. 42 , D490 – D495 . 10.1093/nar/gkt1178 24270786
Lorca G. L. Barabote R. D. Zlotopolski V. Tran C. Winnen B. Hvorup R. N. JR. . ( 2007 ). Transport capabilities of eleven gram-positive bacteria: comparative genomic analyses . Biochim. Biophys. Acta 1768 , 1342 – 1366 . 10.1016/j.bbamem.2007.02.007 17490609
Louis P. Young P. Holtrop G. Flint H. J. ( 2010 ). Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene . Environ. Microbiol. 12 , 304 – 314 . 10.1111/j.1462-2920.2009.02066.x 19807780
Maguin E. Duwat P. Hege T. Ehrlich D. Gruss A. ( 1992 ). New thermosensitive plasmid for gram-positive bacteria . J. Bacteriol. 174 , 5633 – 5638 . 1324906
Margolles A. De Los Reyes-Gavilan C. G. ( 2003 ). Purification and functional characterization of a novel alpha-L-arabinofuranosidase from Bifidobacterium longum B667 . Appl. Environ. Microbiol. 69 , 5096 – 5103 . 10.1128/AEM.69.9.5096-5103.2003 12957891
Marteau P. Cuillerier E. Meance S. Gerhardt M. F. Myara A. Bouvier M. . ( 2002 ). Bifidobacterium animalis strain DN-173 010 shortens the colonic transit time in healthy women: a double-blind, randomized, controlled study . Aliment. Pharmacol. Ther. 16 , 587 – 593 . 10.1046/j.1365-2036.2002.01188.x 11876714
Meance S. Cayuela C. Turchet P. Raimondi A. Lucas C. Antoine J.-M. ( 2011 ). A fermented milk with a Bifidobacterium probiotic strain DN-173 010 shortened oro-fecal gut transit time in elderly . Microb. Ecol. Health Dis. 13 , 217 – 222 .
Menne E. Guggenbuhl N. Roberfroid M. ( 2000 ). Fn-type chicory inulin hydrolysate has a prebiotic effect in humans . J. Nutr. 130 , 1197 – 1199 . 10801918
Milani C. Andrea Lugli G. Duranti S. Turroni F. Mancabelli L. Ferrario C. . ( 2015 ). Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut . Sci. Rep. 5 , 15782 . 10.1038/srep15782 26506949
Milani C. Lugli G. A. Duranti S. Turroni F. Bottacini F. Mangifesta M. . ( 2014 ). Genomic encyclopedia of type strains of the genus bifidobacterium . Appl. Environ. Microbiol. 80 , 6290 – 6302 . 10.1128/AEM.02308-14 25085493
Moura P. Barata R. Carvalheiro F. Girio F. Loureiro-Dias M. C. Esteves M. P. ( 2007 ). In vitro fermentation of xylo-oligosaccharides from corn cobs autohydrolysis by Bifidobacterium and Lactobacillus strains . Lwt-Food Sci. Technol. 40 , 963 – 972 . 10.1016/j.lwt.2006.07.013
Neyrinck A. M. Possemiers S. Druart C. Van De Wiele T. De Backer F. Cani P. D. . ( 2011 ). Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides / Prevotella in diet-induced obese mice . PLoS ONE 6 : e20944 . 10.1371/journal.pone.0020944 21695273
O'Connell K. J. O'Connell Motherway M. Liedtke A. Fitzgerald G. F. Ross R. P. Stanton C. . ( 2014 ). Transcription of two adjacent carbohydrate utilization gene clusters in Bifidobacterium breve UCC2003 Is controlled by laci- and Repressor Open Reading Frame Kinase (ROK)-Type regulators . Appl. Environ. Microbiol. 80 , 3604 – 3614 . 10.1128/AEM.00130-14 24705323
O'Connell K. J. O'Connell Motherway M. O'Callaghan J. Fitzgerald G. F. Ross R. P. Ventura M. . ( 2013 ). Metabolism of four alpha-glycosidic linkage-containing oligosaccharides by Bifidobacterium breve UCC2003 . Appl. Environ. Microbiol. 79 , 6280 – 6292 . 10.1128/AEM.01775-13 23913435
O'Connell Motherway M. Fitzgerald G. F. Neirynck S. Ryan S. Steidler L. Van Sinderen D. ( 2008 ). Characterization of ApuB, an extracellular type II amylopullulanase from Bifidobacterium breve UCC2003 . Appl. Environ. Microbiol. 74 , 6271 – 6279 . 10.1128/AEM.01169-08 18689518
O'Connell Motherway M. Fitzgerald G. F. Van Sinderen D. ( 2011a ). Metabolism of a plant derived galactose-containing polysaccharide by Bifidobacterium breve UCC2003 . Microb. Biotechnol. 4 , 403 – 416 . 10.1111/j.1751-7915.2010.00218.x 21375716
O'Connell Motherway M. Kinsella M. Fitzgerald G. F. Sinderen D. ( 2013 ). Transcriptional and functional characterization of genetic elements involved in galacto-oligosaccharide utilization by Bifidobacterium breve UCC2003 . Microb. Biotechnol. 6 , 67 – 79 . 10.1111/1751-7915.12011 23199239
O'Connell Motherway M. O'Driscoll J. Fitzgerald G. F. Van Sinderen D. ( 2009 ). Overcoming the restriction barrier to plasmid transformation and targeted mutagenesis in Bifidobacterium breve UCC2003 . Microb. Biotechnol. 2 , 321 – 332 . 10.1111/j.1751-7915.2008.00071.x 21261927
O'Connell Motherway M. Zomer A. Leahy S. C. Reunanen J. Bottacini F. Claesson M. J. . ( 2011b ). Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor . Proc. Natl. Acad. Sci. U.S.A. 108 , 11217 – 11222 . 10.1073/pnas.1105380108 21690406
O'Hara A. M. Shanahan F. ( 2007 ). Mechanisms of action of probiotics in intestinal diseases . Sci. World J. 7 , 31 – 46 . 10.1100/tsw.2007.26 17221140
Ott S. J. Musfeldt M. Wenderoth D. F. Hampe J. Brant O. Folsch U. R. . ( 2004 ). Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease . Gut 53 , 685 – 693 . 10.1136/gut.2003.025403 15082587
Ouwehand A. C. Salminen S. Isolauri E. ( 2002 ). Probiotics: an overview of beneficial effects . Antonie Van Leeuwenhoek 82 , 279 – 289 . 10.1023/A:1020620607611 12369194
Palframan R. J. Gibson G. R. Rastall R. A. ( 2003 ). Carbohydrate preferences of Bifidobacterium species isolated from the human gut . Curr. Issues Intest. Microbiol. 4 , 71 – 75 . 14503691
Parche S. Amon J. Jankovic I. Rezzonico E. Beleut M. Barutcu H. . ( 2007 ). Sugar transport systems of Bifidobacterium longum NCC2705 . J. Mol. Microbiol. Biotechnol. 12 , 9 – 19 . 10.1159/000096455 17183207
Parche S. Beleut M. Rezzonico E. Jacobs D. Arigoni F. Titgemeyer F. . ( 2006 ). Lactose-over-glucose preference in Bifidobacterium longum NCC2705: glcP, encoding a glucose transporter, is subject to lactose repression . J. Bacteriol. 188 , 1260 – 1265 . 10.1128/JB.188.4.1260-1265.2006 16452407
Patel R. Dupont H. L. ( 2015 ). New Approaches for Bacteriotherapy: prebiotics, new-generation probiotics, and synbiotics . Clin. Infect. Dis. 60 , S108 – S121 . 10.1093/cid/civ177 25922396
Patole S. K. Rao S. C. Keil A. D. Nathan E. A. Doherty D. A. Simmer K. N. ( 2016 ). Benefits of Bifidobacterium breve M-16V supplementation in preterm neonates - a retrospective cohort study . PLoS ONE 11 : e0150775 . 10.1371/journal.pone.0150775 26953798
Perdigon G. Alvarez S. Rachid M. Aguero G. Gobbato N. ( 1995 ). Immune system stimulation by probiotics . J. Dairy Sci. 78 , 1597 – 1606 . 10.3168/jds.S0022-0302(95)76784-4 7593855
Picard C. Fioramonti J. Francois A. Robinson T. Neant F. Matuchansky C. ( 2005 ). Review article: bifidobacteria as probiotic agents – physiological effects and clinical benefits . Aliment. Pharmacol. Ther. 22 , 495 – 512 . 10.1111/j.1365-2036.2005.02615.x 16167966
Pokusaeva K. Fitzgerald G. F. Van Sinderen D. ( 2011a ). Carbohydrate metabolism in Bifidobacteria. Genes Nutr. 6 , 285 – 306 . 10.1007/s12263-010-0206-6 21484167
Pokusaeva K. Neves A. R. Zomer A. O'Connell-Motherway M. Macsharry J. Curley P. . ( 2010 ). Ribose utilization by the human commensal Bifidobacterium breve UCC2003 . Microb. Biotechnol. 3 , 311 – 323 . 10.1111/j.1751-7915.2009.00152.x 21255330
Pokusaeva K. O'Connell-Motherway M. Zomer A. Macsharry J. Fitzgerald G. F. Van Sinderen D. ( 2011b ). Cellodextrin utilization by bifidobacterium breve UCC2003 . Appl. Environ. Microbiol. 77 , 1681 – 1690 . 10.1128/AEM.01786-10 21216899
Pool-Zobel B. L. Neudecker C. Domizlaff I. Ji S. Schillinger U. Rumney C. . ( 1996 ). Lactobacillus- and bifidobacterium -mediated antigenotoxicity in the colon of rats . Nutr. Cancer 26 , 365 – 380 . 10.1080/01635589609514492 8910918
Postma P. W. Lengeler J. W. Jacobson G. R. ( 1993 ). Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria . Microbiol. Rev. 57 , 543 – 594 . 8246840
Rafter J. Bennett M. Caderni G. Clune Y. Hughes R. Karlsson P. C. . ( 2007 ). Dietary synbiotics reduce cancer risk factors in polypectomized and colon cancer patients . Am. J. Clin. Nutr. 85 , 488 – 496 . 17284748
Rastall R. A. Gibson G. R. ( 2015 ). Recent developments in prebiotics to selectively impact beneficial microbes and promote intestinal health . Curr. Opin. Biotechnol. 32 , 42 – 46 . 10.1016/j.copbio.2014.11.002 25448231
Ravcheev D. A. Khoroshkin M. S. Laikova O. N. Tsoy O. V. Sernova N. V. Petrova S. A. . ( 2014 ). Comparative genomics and evolution of regulons of the LacI-family transcription factors . Front. Microbiol. 5 : 294 . 10.3389/fmicb.2014.00294 24966856
Reichardt N. Duncan S. H. Young P. Belenguer A. Mcwilliam Leitch C. Scott K. P. . ( 2014 ). Phylogenetic distribution of three pathways for propionate production within the human gut microbiota . ISME J. 8 , 1323 – 1335 . 10.1038/ismej.2014.14 24553467
Rivière A. Gagnon M. Weckx S. Roy D. De Vuyst L. ( 2015 ). Mutual cross-feeding interactions between Bifidobacterium longum NCC2705 and eubacterium rectale ATCC 33656 explain the bifidogenic and butyrogenic effects of arabinoxylan-oligosaccharides . Appl. Environ. Microbiol. 22 , 7767 – 7781 . 10.1128/AEM.02089-15 26319874
Riviere A. Moens F. Selak M. Maes D. Weckx S. De Vuyst L. ( 2014 ). The ability of bifidobacteria to degrade arabinoxylan oligosaccharide constituents and derived oligosaccharides is strain dependent . Appl. Environ. Microbiol. 80 , 204 – 217 . 10.1128/AEM.02853-13 24141124
Roberfroid M. B. Bornet F. Bouley C. Cummings J. H. ( 1995 ). Colonic microflora: nutrition and health. Summary and conclusions of an International Life Sciences Institute (ILSI) [Europe] workshop held in Barcelona, Spain . Nutr. Rev. 53 , 127 – 130 . 10.1111/j.1753-4887.1995.tb01535.x 7666984
Roberfroid M. Gibson G. R. Hoyles L. Mccartney A. L. Rastall R. Rowland I. ( 2010 ). Prebiotic effects: metabolic and health benefits . Br. J. Nutr. 104 ( Suppl. 2 ), S1 – S63 . 10.1017/s0007114510003363 20920376
Rowland I. R. Rumney C. J. Coutts J. T. Lievense L. C. ( 1998 ). Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats . Carcinogenesis 19 , 281 – 285 . 10.1093/carcin/19.2.281 9498277
Ruiz L. Motherway M. O. Lanigan N. Van Sinderen D. ( 2013 ). Transposon mutagenesis in Bifidobacterium breve: construction and characterization of a Tn5 transposon mutant library for B ifidobacterium breve UCC2003 . PLoS ONE 8 : e64699 . 10.1371/journal.pone.0064699 23737995
Ryan S. M. Fitzgerald G. F. Van Sinderen D. ( 2005 ). Transcriptional regulation and characterization of a novel β-fructofuranosidase-encoding gene from Bifidobacterium breve UCC2003 . Appl. Environ. Microbiol. 71 , 3475 – 3482 . 10.1128/AEM.71.7.3475-3482.2005 16000751
Saier M. H. Jr. Ramseier T. M. ( 1996 ). The catabolite repressor/activator (Cra) protein of enteric bacteria . J. Bacteriol. 178 , 3411 – 3417 . 8655535
Sakaguchi K. He J. Tani S. Kano Y. Suzuki T. ( 2012 ). A targeted gene knockout method using a newly constructed temperature-sensitive plasmid mediated homologous recombination in Bifidobacterium longum . Appl. Microbiol. Biotechnol. 95 , 499 – 509 . 10.1007/s00253-012-4090-4 22639142
Salminen S. Wright A. V. ( 1998 ). Lactic Acid Bacteria : Microbiology And Functional Aspects New York, NY : Marcel Dekker ).
Satokari R. M. Vaughan E. E. Smidt H. Saarela M. Matto J. De Vos W. M. ( 2003 ). Molecular approaches for the detection and identification of bifidobacteria and lactobacilli in the human gastrointestinal tract . Syst. Appl. Microbiol. 26 , 572 – 584 . 10.1078/072320203770865882 14666986
Schell M. A. Karmirantzou M. Snel B. Vilanova D. Berger B. Pessi G. . ( 2002 ). The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract . Proc. Natl. Acad. Sci. U.S.A. 99 , 14422 – 14427 . 10.1073/pnas.212527599 12381787
Schroder G. Lanka E. ( 2005 ). The mating pair formation system of conjugative plasmids-A versatile secretion machinery for transfer of proteins and DNA . Plasmid 54 , 1 – 25 . 10.1016/j.plasmid.2005.02.001 15907535
Sekine K. Toida T. Saito M. Kuboyama M. Kawashima T. Hashimoto Y. ( 1985 ). A new morphologically characterized cell wall preparation (whole peptidoglycan) from Bifidobacterium infantis with a higher efficacy on the regression of an established tumor in Mice . Cancer Res. 45 , 1300 – 1307 . 3971375
Sela D. A. ( 2011 ). Bifidobacterial utilization of human milk oligosaccharides . Int. J. Food Microbiol. 149 , 58 – 64 . 10.1016/j.ijfoodmicro.2011.01.025 21342711
Sela D. A. Chapman J. Adeuya A. Kim J. H. Chen F. Whitehead T. R. . ( 2008 ). The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome . Proc. Natl. Acad. Sci. U.S.A. 105 , 18964 – 18969 . 10.1073/pnas.0809584105 19033196
Serafini F. Turroni F. Guglielmetti S. Gioiosa L. Foroni E. Sanghez V. . ( 2012 ). An efficient and reproducible method for transformation of genetically recalcitrant bifidobacteria . FEMS Microbiol. Lett. 333 , 146 – 152 . 10.1111/j.1574-6968.2012.02605.x 22640171
Shkoporov A. N. Efimov B. A. Khokhlova E. V. Steele J. L. Kafarskaia L. I. Smeianov V. V. ( 2008 ). Characterization of plasmids from human infant Bifidobacterium strains : sequence analysis and construction of E. coli-Bifidobacterium shuttle vectors . Plasmid 60 , 136 – 148 . 10.1016/j.plasmid.2008.06.005 18652842
Simon G. L. Gorbach S. L. ( 1984 ). Intestinal flora in health and disease . Gastroenterology 86 , 174 – 193 . 6357937
Steed H. Macfarlane G. T. Blackett K. L. Bahrami B. Reynolds N. Walsh S. V. . ( 2010 ). Clinical trial: the microbiological and immunological effects of synbiotic consumption - a randomized double-blind placebo-controlled study in active Crohn's disease . Aliment. Pharmacol. Ther. 32 , 872 – 883 . 10.1111/j.1365-2036.2010.04417.x 20735782
Sun Z. Baur A. Zhurina D. Yuan J. Riedel C. U. ( 2012 ). Accessing the inaccessible: molecular tools for bifidobacteria . Appl. Environ. Microbiol. 78 , 5035 – 5042 . 10.1128/AEM.00551-12 22582076
Suzuki H. Murakami A. Yoshida K. ( 2013 ). Motif-guided identification of a glycoside hydrolase family 1 alpha-L-arabinofuranosidase in Bifidobacterium adolescentis . Biosci. Biotechnol. Biochem. 77 , 1709 – 1714 . 10.1271/bbb.130279 23924734
Szostková M. Horáková D. ( 1998 ). The effect of plasmid DNA sizes and other factors on electrotransformation of Escherichia coli JM109 . Bioelectrochem. Bioenerg. 47 , 319 – 323 . 10.1016/S0302-4598(98)00203-7
Takamatsu D. Osaki M. Sekizaki T. ( 2001 ). Thermosensitive suicide vectors for gene replacement in Streptococcus suis . Plasmid 46 , 140 – 148 . 10.1006/plas.2001.1532 11591139
Tanaka R. Takayama H. Morotomi M. Kuroshima T. Ueyama S. Matsumoto K. ( 1983 ). Effects of administration of TOS and Bifidobacterium breve on the human fecal flora . Bifidobacteria and Microflora, 2 , 17 – 24 . 10.12938/bifidus1982.2.1_17
Tavan E. Cayuela C. Antoine J. M. Cassand P. ( 2002 ). Antimutagenic activities of various lactic acid bacteria against food mutagens: heterocyclic amines . J. Dairy Res. 69 , 335 – 341 . 10.1017/S002202990200540X 12222811
Teitelbaum J. E. Walker W. A. ( 2002 ). Nutritional impact of pre- and probiotics as protective gastrointestinal organisms . Annu. Rev. Nutr. 22 , 107 – 138 . 10.1146/annurev.nutr.22.110901.145412 12055340
Trindade M. I. Abratt V. R. Reid S. J. ( 2003 ). Induction of sucrose utilization genes from Bifidobacterium lactis by sucrose and raffinose . Appl. Environ. Microbiol. 69 , 24 – 32 . 10.1128/AEM.69.1.24-32.2003 12513973
Truchado P. Van Den Abbeele P. Riviere A. Possemiers S. De Vuyst L. Van De Wiele T. ( 2015 ). Bifidobacterium longum D2 enhances microbial degradation of long-chain arabinoxylans in an in vitro model of the proximal colon . Benef. Microbes 6 , 1 – 12 . 10.3920/BM2015.0023 25488373
Turroni F. Bottacini F. Foroni E. Mulder I. Kim J. H. Zomer A. . ( 2010 ). Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging . Proc. Natl. Acad. Sci. U.S.A. 107 , 19514 – 19519 . 10.1073/pnas.1011100107 20974960
Turroni F. Milani C. Duranti S. Mancabelli L. Mangifesta M. Viappiani A. . ( 2016 ). Deciphering bifidobacterial-mediated metabolic interactions and their impact on gut microbiota by a multi-omics approach . ISME J. . [Epub ahead of print]. 10.1038/ismej.2015.236 26859770
Turroni F. Strati F. Foroni E. Serafini F. Duranti S. Van Sinderen D. . ( 2012 ). Analysis of predicted carbohydrate transport systems encoded by Bifidobacterium bifidum PRL2010 . Appl. Environ. Microbiol. 78 , 5002 – 5012 . 10.1128/AEM.00629-12 22562993
Van Den Abbeele P. Gerard P. Rabot S. Bruneau A. El Aidy S. Derrien M. . ( 2011 ). Arabinoxylans and inulin differentially modulate the mucosal and luminal gut microbiota and mucin-degradation in humanized rats . Environ. Microbiol. 13 , 2667 – 2680 . 10.1111/j.1462-2920.2011.02533.x 21883787
Van Den Broek L. A. Hinz S. W. Beldman G. Vincken J. P. Voragen A. G. ( 2008 ). Bifidobacterium carbohydrases-their role in breakdown and synthesis of (potential) prebiotics . Mol. Nutr. Food Res. 52 , 146 – 163 . 10.1002/mnfr.200700121 18040988
Van Der Meulen R. Adriany T. Verbrugghe K. De Vuyst L. ( 2006a ). Kinetic analysis of bifidobacterial metabolism reveals a minor role for succinic acid in the regeneration of NAD+ through its growth-associated production . Appl. Environ. Microbiol. 72 , 5204 – 5210 . 10.1128/AEM.00146-06 16885266
Van Der Meulen R. Avonts L. De Vuyst L. ( 2004 ). Short fractions of oligofructose are preferentially metabolized by Bifidobacterium animalis DN-173 010 . Appl. Environ. Microbiol. 70 , 1923 – 1930 . 10.1128/AEM.70.4.1923-1930.2004 15066781
Van Der Meulen R. Makras L. Verbrugghe K. Adriany T. De Vuyst L. ( 2006b ). In vitro kinetic analysis of oligofructose consumption by Bacteroides and Bifidobacterium spp. indicates different degradation mechanisms . Appl. Environ. Microbiol. 72 , 1006 – 1012 . 10.1128/AEM.72.2.1006-1012.2006 16461642
Van Laere K. M. Beldman G. Voragen A. G. ( 1997 ). A new arabinofuranohydrolase from Bifidobacterium adolescentis able to remove arabinosyl residues from double-substituted xylose units in arabinoxylan . Appl. Microbiol. Biotechnol. 47 , 231 – 235 . 10.1007/s002530050918 9114514
Van Laere K. M. Hartemink R. Bosveld M. Schols H. A. Voragen A. G. ( 2000 ). Fermentation of plant cell wall derived polysaccharides and their corresponding oligosaccharides by intestinal bacteria . J. Agric. Food Chem. 48 , 1644 – 1652 . 10.1021/jf990519i 10820072
Van Laere K. M. J. Voragen C. H. L. Kroef T. Van Den Broek L. A. M. Beldman G. Voragen A. G. J. ( 1999 ). Purification and mode of action of two different arabinoxylan arabinofuranohydrolases from Bifidobacterium adolescentis DSM 20083 . Appl. Microbiol. Biotechnol. 51 , 606 – 613 . 10.1007/s002530051439
Vaughan E. E. Heilig H. G. Ben-Amor K. De Vos W. M. ( 2005 ). Diversity, vitality and activities of intestinal lactic acid bacteria and bifidobacteria assessed by molecular approaches . FEMS Microbiol. Rev. 29 , 477 – 490 . 10.1016/j.fmrre.2005.04.009 16125009
Veereman-Wauters G. Staelens S. Van De Broek H. Plaskie K. Wesling F. Roger L. C. . ( 2011 ). Physiological and bifidogenic effects of prebiotic supplements in infant formulae . J. Pediatr. Gastroenterol. Nutr. 52 , 763 – 771 . 10.1097/MPG.0b013e3182139f39 21593649
Ventura M. Canchaya C. Tauch A. Chandra G. Fitzgerald G. F. Chater K. F. . ( 2007 ). Genomics of Actinobacteria : tracing the evolutionary history of an ancient phylum . Microbiol. Mol. Biol. Rev. 71 , 495 – 548 . 10.1128/MMBR.00005-07 17804669
Ventura M. Turroni F. Lugli G. A. Van Sinderen D. ( 2014 ). Bifidobacteria and humans: our special friends, from ecological to genomics perspectives . J. Sci. Food Agric. 94 , 163 – 168 . 10.1002/jsfa.6356 23963950
Ventura M. Van Sinderen D. Fitzgerald G. F. Zink R. ( 2004 ). Insights into the taxonomy, genetics and physiology of bifidobacteria . Antonie Van Leeuwenhoek 86 , 205 – 223 . 10.1023/B:ANTO.0000047930.11029.ec 15539925
Venturi A. Gionchetti P. Rizzello F. Johansson R. . ( 1999 ). Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis . Aliment. Pharmacol. Ther. 13 , 1103 – 1108 . 10.1046/j.1365-2036.1999.00560.x 10468688
Walton G. E. Lu C. Trogh I. Arnaut F. Gibson G. R. ( 2012 ). A randomised, double-blind, placebo controlled cross-over study to determine the gastrointestinal effects of consumption of arabinoxylan-oligosaccharides enriched bread in healthy volunteers . Nutr. J. 11 , 36 . 10.1186/1475-2891-11-36 22657950
Wong J. M. De Souza R. Kendall C. W. Emam A. Jenkins D. J. ( 2006 ). Colonic health: fermentation and short chain fatty acids . J. Clin. Gastroenterol. 40 , 235 – 243 . 10.1097/00004836-200603000-00015 16633129
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
오픈액세스 학술지에 출판된 논문
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.