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Synthesis, Anti‐inflammatory, and Arginase Inhibitory Activity of Piceatannol and Its Analogs 원문보기

Bulletin of the Korean chemical society, v.38 no.3, 2017년, pp.342 - 349  

Moon, Insu (Department of Chemistry and Institute of Applied Chemistry Hallym University Chuncheon 24252 Korea) ,  Damodar, Kongara (Department of Chemistry and Institute of Applied Chemistry Hallym University Chuncheon 24252 Korea) ,  Kim, Jin‐Kyung (Department of Biomedical Science, College of Natural Science Catholic University of Daegu Gyeungsan‐) ,  Ryoo, Sungwoo (Si 38430 Korea) ,  Jun, Jong‐Gab (Department of Medical Biotechnology, College of Biomedical Science Kangwon National University Chuncheon 24341 Korea)

Abstract AI-Helper 아이콘AI-Helper

The present study describes the synthesis of piceatannol (2) and its analogs (3-8) using Wittig‐Horner reaction, Colvin rearrangement, and Sonogashira reaction as key steps and also evaluation of their inhibitory potency on the production of inflammatory mediator nitric oxide (NO) in lipopoly...

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