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Butyrate reduces high-fat diet-induced metabolic alterations, hepatic steatosis and pancreatic beta cell and intestinal barrier dysfunctions in prediabetic mice 원문보기

Experimental biology and medicine, v.242 no.12, 2017년, pp.1214 - 1226  

Matheus, VA (Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Sã) ,  Monteiro, LCS (o Paulo, CEP 13083-970, Brazil) ,  Oliveira, RB (Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Sã) ,  Maschio, DA (o Paulo, CEP 13083-970, Brazil) ,  Collares-Buzato, CB (Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Sã)

Abstract AI-Helper 아이콘AI-Helper

In this study, we investigated the effect of diet supplementation with sodium butyrate (5% w/w), a short-chain fatty acid produced by the intestinal microbiota, on metabolic parameters, body adiposity, hepatic and pancreatic lipid accumulation, beta cell function/mass as well as on the structure an...

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