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Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles 원문보기

Journal of visualized experiments : JoVE, no.129, 2017년, pp.56596 -   

Madasamy, Shanmugavel (Plaxgen Inc) ,  Liu, David (Plaxgen Inc) ,  Lundry, Jason (Plaxgen Inc) ,  Alderete, Benjamin (Millipore Sigma) ,  Kong, Raymond (Millipore Sigma) ,  Robinson, J. Paul (Cytometry Laboratories, Purdue University) ,  Wu, Alan H.B. (Plaxgen Inc) ,  Amento, Edward P. (Molecular Medicine Research Institute)

Abstract AI-Helper 아이콘AI-Helper

Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma. However, a possible role of these drugs in altering morphology and di...

참고문헌 (31)

  1. Pahan K Lipid-lowering drugs Cell Mol Life Sci 2006 63 1165 1178 16568248 

  2. Laforest L Prevalence of low high-density lipoprotein cholesterol and hypertriglyceridaemia in patients treated with hypolipidaemic drugs Arch Cardiovasc Dis 2009 102 43 50 19233108 

  3. Roberts WC Preventing and arresting coronary atherosclerosis Am Heart J 1995 130 580 600 7661078 

  4. Goldstein JL Brown MS A century of cholesterol and coronaries: from plaques to genes to statins Cell 2015 16 161 172 

  5. Drexel H Statins, fibrates, nicotinic acid, cholesterol absorption inhibitors, anion-exchange resins, omega-3 fatty acids: which drugs for which patients? Fundam Clin Pharmacol 2009 23 687 692 19682084 

  6. Camelia S Anca S Statins: Mechanism of action and effects J.Cell.Mol.Med 2001 5 378 387 12067471 

  7. Schaefer EJ Comparisons of effects of statins (atorvastatin, fluvastatin, lovastatin, pravastatin, and simvastatin) on fasting and postprandial lipoproteins in patients with coronary heart disease versus control subjects Am J Cardiol 2004 93 31 39 14697462 

  8. Meyers CD Kamanna VS Kashyap ML Niacin therapy in atherosclerosis Curr Opin in Lipid 2004 15 659 665 

  9. Phan BA Dayspringm TD Toth PP Ezetimibe therapy: mechanism of action and clinical update Vasc Health Risk Mana 2012 8 415 427 

  10. Leitersdorf E Fruchart JC Mechanism of action of fibrates on lipid and lipoprotein metabolism Circulation 1998 98 2088 2093 9808609 

  11. Backes J Anzalone D Hilleman D Catini J The clinical relevance of omega-3 fatty acids in the management of hypertriglyceridemia Lipids Health Dis 2016 15 118 27444154 

  12. Davidson MH Clinical Significance of Statin Pleiotropic Effects Hypotheses Versus Evidence Circulation 2005 111 2280 2281 15883224 

  13. Chinetti-Gbaguidi G Fruchart JC Staels B Pleiotropic effects of fibrates Curr Atheroscler Rep 2005 7 396 401 16105484 

  14. McTaggart F Jones P Effects of Statins on High-Density Lipoproteins: A Potential Contribution to Cardiovascular Benefit Effects of Statins on High-Density Lipoproteins: A Potential Contribution to Cardiovascular Benefit CardiovascDrugs Ther 2008 22 321 338 

  15. Quehenberger O The Human Plasma Lipidome N Engl J Med 2011 365 1812 1823 22070478 

  16. Lund-Katz S Mechanisms responsible for the compositional heterogeneity of nascent high density lipoprotein J. Biol Chem 2013 288 23150 23160 23836906 

  17. Krauss RM Lipoprotein subfractions and cardiovascular disease risk Curr Opin Lipidol 2010 21 305 311 20531184 

  18. Krauss RM Burke DJ Identification of multiple subclasses of plasma low density lipoproteins in normal humans J Lipid Res 1982 23 97 104 7057116 

  19. Rosenson RS HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular Events Clinic Chemi 2011 57 392 410 

  20. Madasamy S Plaque array method and proteomics-based identification of biomarkers from Alzheimer's disease serum Clin Chim Acta 2015 441 79 85 25532947 

  21. Madasamy S Nonenzymatic Mechanism of Statins in Modulating Cholesterol Particles Formation Am J Cardiol 2016 118 1187 1191 27614849 

  22. Peter OK Clinical relevance of the biochemical, metabolic, and genetic factors that influence low-density lipoprotein heterogeneity Am J Cardiol 2002 90 30 47 

  23. Weissglas-Volkov D Pajukanta P Genetic causes of high and low serum HDL-cholesterol J Lipid Res 2010 51 2032 2057 20421590 

  24. Abela GS Effect of statins on cholesterol crystallization and atherosclerotic plaque stabilization Am J Cardiol 2011 107 1710 1717 21507364 

  25. Nidorf SM Eikelboom JW Thompson PL Targeting cholesterol crystal-induced inflammation for the secondary prevention of cardiovascular disease Cardiovasc Pharmacol Ther 2014 19 45 52 

  26. Thacker SG Zarzour A Chen High density lipoprotein reduces inflammation from cholesterol crystals by inhibiting inflammasome activation Immunol 2016 149 306 319 

  27. Kim SH Lee ES Lee JY Multiplex coherent anti-stokes Raman Spectroscopy images intact atheromatous lesions and concomitantly identifies distinct chemical profiles of atherosclerotic lipids Circ Res 2010 106 1332 1341 20299664 

  28. Lim RS Suhalim JL Miyazaki-Anzai S Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging J Lipid Res 2011 52 2177 2186 21949051 

  29. Rothblat GH Phillips MC High-density lipoprotein heterogeneity and function in reverse cholesterol transport Curr Opin Lipidol 2011 21 229 238 

  30. Kontush A HDL particle number and size as predictors of cardiovascular disease Front in Pharmacol 2015 

  31. Karathanasis SK Freeman LA Gordon SM Remaley AT The changing face of HDL and the best way to measure it Clin. Chem 2017 63 196 210 27879324 

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