[논문]Pharmacoacupuncture for Idiopathic Parkinson's Disease: A Systematic Review of Randomized Controlled Trials

Cho, Ki-Ho; Kim, Tae-Hun; Jung, Woo-Sang; Moon, Sang-Kwan; Ko, Chang-Nam; Cho, Seung-Yeon; Jeon, Chan-Yong; Choi, Tae Young; Lee, Myeong Soo; Lee, Sang-Ho; Chung, Eun Kyoung; Kwon, Seungwon

doi:10.1155/2018/3671542

Pharmacoacupuncture for Idiopathic Parkinson's Disease: A Systematic Review of Randomized Controlled Trials 원문보기

Evidence-based Complementary and Alternative Medicine : eCAM, v.2018, 2018년, pp.3671542 -

Cho, Ki-Ho (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea) , Kim, Tae-Hun (Korean Medicine Clinical Trial Center, Korean Medicine Hospital, Kyung Hee University, Seoul, Republic of Korea) , Jung, Woo-Sang (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea) , Moon, Sang-Kwan (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea) , Ko, Chang-Nam (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea) , Cho, Seung-Yeon (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea) , Jeon, Chan-Yong (Department of Korean Internal Medicine, College of Korean Medicine, Gachon University, Seongnam, Republic of Korea) , Choi, Tae Young (Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea) , Lee, Myeong Soo (Clinical Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Ko) , Lee, Sang-Ho , Chung, Eun Kyoung , Kwon, Seungwon

Abstract ▼ AI-Helper

Introduction Pharmacoacupuncture is a new acupuncture treatment that stimulates acupuncture points by injecting herbal medicine into them. Recently, pharmacoacupuncture has been widely used in the treatment of idiopathic Parkinson's disease in traditional East Asian medicine. The purpose of this systematic review is to evaluate the efficacy and safety of pharmacoacupuncture in the treatment of idiopathic Parkinson's disease. Methods The following electronic databases were searched for studies published in or before December 2016: Medline, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, OASIS, and CNKI, without language restriction. The main outcome assessed was the total Unified Parkinson's Disease Rating Scale (UPDRS) score. The details of the pharmacoacupuncture intervention, such as the herbal medicine and acupuncture points used, were also investigated. Results From 138 studies, 3 randomized controlled trials were included; the number of patients analyzed was 134. Most of the studies showed considerable methodological flaws. There was heterogeneity of the intervention type and treatment duration in the included studies. Therefore, we could not conduct a meta-analysis. In one study, adjunctive bee venom pharmacoacupuncture therapy significantly improved total UPDRS scores compared with conventional therapy alone. Another study, which used adjunctive Kakkonein pharmacoacupuncture, did not reveal significant improvement compared with conventional therapy alone. A third study reported that Mailuoning pharmacoacupuncture was able to significantly improve the modified Webster Symptom Score when compared with no treatment. Adverse events related to the pharmacoacupuncture were reported in only one case, itching caused by the bee venom. Conclusions Our findings regarding the efficacy of pharmacoacupuncture as a therapy for idiopathic Parkinson's disease are currently inconclusive. Further large and rigorous clinical trials are needed.

참고문헌 (21)

1 Sveinbjornsdottir S. The clinical symptoms of Parkinson’s disease Journal of Neurochemistry 2016 318 324 10.1111/jnc.13691 2-s2.0-84991256087 27401947

상세보기
2 Bastide M. F. Meissner W. G. Picconi B. Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease Progress in Neurobiology 2015 132 96 168 2-s2.0-84940452532 10.1016/j.pneurobio.2015.07.002 26209473

상세보기
3 Burn D. J. Tröster A. I. Neuropsychiatric complications of medical and surgical therapies for parkinson’s disease Journal of Geriatric Psychiatry and Neurology 2004 17 3 172 180 10.1177/0891988704267466 15312281

상세보기
4 Park C. K. Jung N. Y. Kim M. Chang J. W. Analysis of delayed intracerebral hemorrhage associated with deep brain stimulation surgery World Neurosurgery 2017 104 537 544 10.1016/j.wneu.2017.05.075 2-s2.0-85020257240 28536064

상세보기
5 Wang Y. Xie C.-L. Wang W.-W. Epidemiology of complementary and alternative medicine use in patients with Parkinson’s disease Journal of Clinical Neuroscience 2013 20 8 1062 1067 10.1016/j.jocn.2012.10.022 2-s2.0-84879899501 23815871

상세보기
6 Park J. Lee H. Shin B.-C. Lee M. S. Kim B. Kim J.-I. Pharmacopuncture in Korea: a systematic review and meta-analysis of randomized controlled trials Evidence-Based Complementary and Alternative Medicine 2016 2016 1 19 4683121 10.1155/2016/4683121 2-s2.0-84961372950

상세보기
7 Lee H. Kim T.-H. Leem J. Acupuncture for heart failure: a systematic review of clinical studies International Journal of Cardiology 2016 222 321 331 10.1016/j.ijcard.2016.07.195 2-s2.0-84980348104 27500758

상세보기
8 Higgins J. P. T. Altman D. G. Gøtzsche P. C. The cochrane collaboration’s tool for assessing risk of bias in randomised trials British Medical Journal 2011 343 7829 d5928 10.1136/bmj.d5928 2-s2.0-84859001212

상세보기
9 Cho S.-Y. Shim S.-R. Rhee H. Y. Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease Parkinsonism & Related Disorders 2012 18 8 948 952 10.1016/j.parkreldis.2012.04.030 2-s2.0-84865582800 22632852

상세보기
10 Liu C.-H. Wang R. Jin Y.-B. Sun Z.-L. Zhou X. He J.-Y. Acupoint injection of kakkonein for early- or mid-stage Parkinson’s disease: a multicenter randomized controlled clinical trial Zhongguo Yi Xue Ke Xue Yuan Yi Xue Qing Bao Yan Jiu Suo Bian Ji 2015 40 1 56 60 2-s2.0-84929024394
11 Xu B. Ma C. Chen G. Z. The influence of acupoint injection on central monoamine transmitters in parkinson’s disease Shanghai J Acu-mox 2002 21 2 1 2
12 Nam K. Je K. Lee J. H. Inhibition of COX-2 activity and proinflammatory cytokines (TNF- α and IL-1 β ) production by water-soluble sub-fractionated parts from bee (Apis mellifera) venom Archives of Pharmacal Research 2003 26 5 383 388 10.1007/BF02976695 12785734

원문보기 상세보기
13 Awad K. Abushouk A. I. AbdelKarim A. H. Mohammed M. Negida A. Shalash A. S. Bee venom for the treatment of Parkinson’s disease: how far is it possible? Biomedicine & Pharmacotherapy 2017 91 295 302 10.1016/j.biopha.2017.04.065 2-s2.0-85018948656 28477460

상세보기
14 Doo K.-H. Lee J.-H. Cho S.-Y. A prospective open-label study of combined treatment for idiopathic Parkinson’s disease using acupuncture and bee venom acupuncture as an adjunctive treatment The Journal of Alternative and Complementary Medicine 2015 21 10 598 603 10.1089/acm.2015.0078 2-s2.0-84944060416 26230989

상세보기
15 Hartmann A. Müllner J. Meier N. Bee venom for the treatment of Parkinson disease - A randomized controlled clinical trial PLoS ONE 2016 11 7 2-s2.0-84978878224 10.1371/journal.pone.0158235 e0158235

상세보기
16 Zhang H. Y. Li D. W. Shi C. H. Advances in studies on clinical practice of puerarin Drugs & Clinic 2012 19 2 247 250
17 Yang W. Shi Z. Yang H. Teng J. Zhao J. Xiang G. Mailuoning for acute ischaemic stroke Cochrane Database of Systematic Reviews 2015 1 CD007028 10.1002/14651858.CD007028.pub3

상세보기
18 Yeo S. Choe I.-H. van den Noort M. Acupuncture on GB34 activates the precentral gyrus and prefrontal cortex in Parkinson’s disease BMC Complementary and Alternative Medicine 2014 14, article 336 10.1186/1472-6882-14-336 2-s2.0-84910075082

상세보기
19 Yeo S. Lim S. Choe I.-H. Acupuncture stimulation on GB34 activates neural responses associated with parkinson’s disease CNS Neuroscience & Therapeutics 2012 18 9 781 790 10.1111/j.1755-5949.2012.00363.x 2-s2.0-84865766304 22943145

상세보기
20 Wang H. Pan Y. Xue B. The antioxidative effect of electro-acupuncture in a mouse model of Parkinson's disease PLoS ONE 2011 6 5 2-s2.0-79956367899 10.1371/journal.pone.0019790 e19790

상세보기
21 Nam M. H. Ahn K. S. Choi S. H. Acupuncture stimulation induces neurogenesis in adult brain International Review of Neurobiology 2013 111 67 90 10.1016/B978-0-12-411545-3.00004-3 2-s2.0-84887355346 24215918

상세보기

LOADING...

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Pharmacoacupuncture for Idiopathic Parkinson's Disease: A Systematic Review of Randomized Controlled Trials 원문보기

Abstract ▼ AI-Helper

참고문헌 (21)

이 논문을 인용한 문헌

연구과제 타임라인

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Pharmacoacupuncture for Idiopathic Parkinson's Disease: A Systematic Review of Randomized Controlled Trials 원문보기

Abstract ▼ AI-Helper

참고문헌 (21)

이 논문을 인용한 문헌

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

관련 콘텐츠

원문 보기

원문 URL 링크

오픈액세스(OA) 유형

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트