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NTIS 바로가기Bioorganic chemistry, v.81, 2018년, pp.264 - 269
Yoon, Sun-Young (School of Pharmacy, Sungkyunkwan University) , Lee, Ji Hee (Department of Chemistry, Dongguk University) , Kwon, Se Jeong (School of Pharmacy, Sungkyunkwan University) , Kang, Hyo Jin (Department of Chemistry, Dongguk University) , Chung, Sang J. (School of Pharmacy, Sungkyunkwan University)
Abstract Several protein tyrosine phosphatases (PTPs) that disrupt the insulin-signaling pathway were investigated by siRNAs to identify potential antidiabetic targets. Individual knockdown of PTPN9 and DUSP9 in 3T3-L1 preadipocytes increased AMPK phosphorylation, respectively, and furthermore, con...
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