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NTIS 바로가기Scientia pharmaceutica, v.84 no.3, 2016년, pp.447 - 455
Raghava Reddy, Ambati. V. (Aurobindo Pharma Limited Research Centre-II, Survey No. 71&72, Indrakaran Village, Sangareddy Mandal, Medak District 502329, Telangana, India) , Srinivas, Garaga (srinivasgaraga@yahoo.com (G.S.)) , Takshinamoorthy, Chandiran (chandiran.t@aurobindo.com (C.T.)) , Gupta Peruri, Badarinadh (badari_peruri@yahoo.com (B.G.P.)) , Naidu, Andra (Aurobindo Pharma Limited Research Centre-II, Survey No. 71&72, Indrakaran Village, Sangareddy Mandal, Medak District 502329, Telangana, India)
This paper describes the facile synthesis of sildenafil citrate (1) and its related compounds through an improved chlorosulfonation reaction using chlorosulfonic acid and thionyl chloride. This synthesis results in pure sildenafil with high yield. The structures of the compounds were determined with...
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