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NTIS 바로가기eLife, v.7, 2018년, pp.e32478 -
Hadden, Jodi A (Department of Chemistry and Biochemistry University of Delaware Newark United States) , Perilla, Juan R (Department of Chemistry and Biochemistry University of Delaware Newark United States) , Schlicksup, Christopher John (Department of Molecular and Cellular Biochemistry Indiana University Bloomington United States) , Venkatakrishnan, Balasubramanian (Department of Molecular and Cellular Biochemistry Indiana University Bloomington United States) , Zlotnick, Adam (Department of Molecular and Cellular Biochemistry Indiana University Bloomington United States) , Schulten, Klaus (Department of Physics University of Illinois at Urbana-Champaign Urbana United States)
The hepatitis B virus capsid represents a promising therapeutic target. Experiments suggest the capsid must be flexible to function; however, capsid structure and dynamics have not been thoroughly characterized in the absence of icosahedral symmetry constraints. Here, all-atom molecular dynamics sim...
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