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Scientific reports, v.8, 2018년, pp.14672 -
Mulholland, Theresa (Centre for Microsystems and Photonics, Electronic and Electrical Engineering, University of Strathclyde, Glasgow, G1 1XW UK) , McAllister, Milly (Institute of Cancer Science, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH UK) , Patek, Samantha (Institute of Cancer Science, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH UK) , Flint, David (Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE UK) , Underwood, Mark (Department of Urology, Queen Elizabeth University Hospital, Glasgow, G51 4TF UK) , Sim, Alexander (AMS Biotechnology (Europe) Ltd, Milton Park, Abingdon, OX14 4SE UK) , Edwards, Joanne (Institute of Cancer Science, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G61 1QH UK) , Zagnoni, Michele (Centre for Microsystems and Photonics, Electronic and Electrical Engineering, University of Strathclyde, Glasgow, G1 1XW UK)
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Performing drug screening of tissue derived from cancer patient biopsies using physiologically relevant 3D tumour models presents challenges due to the limited amount of available cell material. Here, we present a microfluidic platform that enables drug screening of cancer cell-enriched multicellula...
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