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NTIS 바로가기ACS omega, v.4 no.3, 2019년, pp.5595 - 5600
Sancho-Fornes, Gabriel (Instituto Interuniversitario de Investigació) , Peris, Ernest (n de Reconocimiento Molecular y Desarrollo Tecnoló) , Giménez-Romero, David (gico (IDM) , Universitat Politè) , Morais, Sergi (cnica de Valè) , Maquieira, Ángel (ncia, Universitat de Valè)
An enzyme inhibition-based assay for drug discovery developed by microarraing on Blu-ray disks is presented. As a proof-of-concept, the system screens a selected molecule library of potential chemical inhibitors against the glycoenzyme peroxidase, identifying the promising lead compounds with high s...
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Copeland PhD, Robert A, Harpel PhD, Mark R, Tummino PhD, Peter J. Targeting enzyme inhibitors in drug discovery. Expert opinion on therapeutic targets, vol.11, no.7, 967-978.
Supuran, Claudiu T.. Advances in structure-based drug discovery of carbonic anhydrase inhibitors. Expert opinion on drug discovery, vol.12, no.1, 61-88.
Chae, Myung-Sic, Yoo, Yong Kyoung, Kim, Jinsik, Kim, Tae Geun, Hwang, Kyo Seon. Graphene-based enzyme-modified field-effect transistor biosensor for monitoring drug effects in Alzheimer’s disease treatment. Sensors and actuators. B, Chemical, vol.272, 448-458.
Kong, Weiheng, Wu, Di, Hu, Na, Li, Ning, Dai, Chunji, Chen, Xuefeng, Suo, Yourui, Li, Guoliang, Wu, Yongning. Robust hybrid enzyme nanoreactor mediated plasmonic sensing strategy for ultrasensitive screening of anti-diabetic drug. Biosensors & bioelectronics, vol.99, 653-659.
Wang, Xing, Zhang, Yuxin, Yang, Ying, Wu, Xia, Fan, Hantian, Qiao, Yanjiang. Identification of berberine as a direct thrombin inhibitor from traditional Chinese medicine through structural, functional and binding studies. Scientific reports, vol.7, 44040-.
Akins, Nicholas S., Nielson, Tanner C., Le, Hoang V.. Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer. Current topics in medicinal chemistry, vol.18, no.6, 494-504.
Rath, Christopher M., Benton, Bret M., de Vicente, Javier, Drumm, Joseph E., Geng, Mei, Li, Cindy, Moreau, Robert J., Shen, Xiaoyu, Skepper, Colin K., Steffek, Micah, Takeoka, Kenneth, Wang, Lisha, Wei, Jun-Rong, Xu, Wenjian, Zhang, Qiong, Feng, Brian Y.. Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics. ACS infectious diseases, vol.4, no.3, 391-402.
Tan, Eu Vian, Lowe, Christopher R.. Holographic Enzyme Inhibition Assays for Drug Discovery. Analytical chemistry, vol.81, no.18, 7579-7589.
Marsh-Armstrong, Brennan, Fajnzylber, Jesse M., Korntner, Samuel, Plaman, Bailey A., Bishop, Anthony C.. The Allosteric Site on SHP2’s Protein Tyrosine Phosphatase Domain is Targetable with Druglike Small Molecules. ACS omega, vol.3, no.11, 15763-15770.
Saleem, Hafiza Nosheen, Batool, Farwa, Mansoor, Hafiz Javed, Shahzad-ul-Hussan, Syed, Saeed, Muhammad. Inhibition of Dengue Virus Protease by Eugeniin, Isobiflorin, and Biflorin Isolated from the Flower Buds of Syzygium aromaticum (Cloves). ACS omega, vol.4, no.1, 1525-1533.
Lu, Hao., Tonge, Peter J.. Inhibitors of FabI, an Enzyme Drug Target in the Bacterial Fatty Acid Biosynthesis Pathway. Accounts of chemical research, vol.41, no.1, 11-20.
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Arnandis-Chover, T., Morais, S., Gonzalez-Martinez, M.A., Puchades, R., Maquieira, A.. High density MicroArrays on Blu-ray discs for massive screening. Biosensors & bioelectronics, vol.51, 109-114.
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Pandey, Binod, Tan, Yih Horng, Fujikawa, Kohki, Demchenko, Alexei V., Stine, Keith J.. Comparative Study of the Binding of Concanavalin A to Self-Assembled Monolayers Containing a Thiolated α-Mannoside on Flat Gold and on Nanoporous Gold. Journal of carbohydrate chemistry, vol.31, no.4, 466-503.
Morais, Sergi, Puchades, Rosa, Maquieira, Ángel. Disc-based microarrays: principles and analytical applications. Analytical and bioanalytical chemistry, vol.408, no.17, 4523-4534.
Avella-Oliver, Miquel, Gimenez-Romero, David, Morais, Sergi, González-Martínez, Miguel Ángel, Bueno, Paulo Roberto, Puchades, Rosa, Maquieira, Ángel. INSEL: an in silico method for optimizing and exploring biorecognition assays. Chemical communications : Chem comm, vol.49, no.92, 10868-10870.
Rusmini, F., Zhong, Z., Feijen, J.. Protein Immobilization Strategies for Protein Biochips. Biomacromolecules, vol.8, no.6, 1775-1789.
Badran, Ahmed Ali, Morais, Sergi, Maquieira, Ángel. Simultaneous determination of four food allergens using compact disc immunoassaying technology. Analytical and bioanalytical chemistry, vol.409, no.9, 2261-2268.
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