[미국특허]
Anti-aging dietary composition containing polysaccharides derived from ginseng and tuber fleeceflower root
원문보기
IPC분류정보
국가/구분
United States(US) Patent
공개
국제특허분류(IPC7판)
A61K-008/97
A23L-001/30
A61Q-019/08
출원번호
US-0615441
(2015-02-06)
공개번호
US-0045428
(2016-02-18)
우선권정보
CN-201410361618.0 (2014-07-28)
발명자
/ 주소
HU, Minghua
LIANG, Ming
LI, Haifeng
MA, Fangli
출원인 / 주소
Infinitus (China) Company Ltd.
인용정보
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0
초록▼
The present invention discloses the use of a ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies, the complex polysaccharide is ginseng and tuber fleeceflower root complex polysaccharide, with ginseng and/or tuber fleeceflowe
The present invention discloses the use of a ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies, the complex polysaccharide is ginseng and tuber fleeceflower root complex polysaccharide, with ginseng and/or tuber fleeceflower root as raw material, the complex polysaccharide is obtained by water extraction, concentration and alcohol precipitation processes. The complex polysaccharide in the present invention, as proved by Caenorhabditis elegans model experiment, is able to prolong the average life span of wild-type, oxidation stress model and protein aggregation toxin model effectively, the effect pathway is closely related to improving anti-oxidation ability in C. elegans, inhibiting toxic aggregation protein stress, enhancing the activity of heat-block protein and regulating the crucial node of insulin signalling pathway, which demonstrates that it has good effect of delaying aging and preventing aging-related diseases.
대표청구항▼
1. A use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies. 2. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim
1. A use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies. 2. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 1, characterized in that, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide in the ginseng and tuber fleeceflower root complex polysaccharide is 1:4-9:1. 3. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 2, characterized in that, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide in the ginseng and tuber fleeceflower root complex polysaccharide is 2:3-2:1. 4. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claims 1, characterized in that, the ginseng and tuber fleeceflower root complex polysaccharide is prepared by the following method: with ginseng or tuber fleeceflower root as raw material, ginseng polysaccharide or tuber fleeceflower root polysaccharide is prepared by processes including water extraction, concentration and alcohol precipitation, then these two polysaccharides are mixed in a stoichiometric ratio, to prepare the ginseng and tuber fleeceflower root complex polysaccharide, or the ginseng and tuber fleeceflower root complex polysaccharide is prepared by the following method: with ginseng and tuber fleeceflower root as raw material, ginseng polysaccharide or tuber fleeceflower root polysaccharide is prepared by processes including water extraction, concentration and alcohol precipitation; the complex polysaccharide has an anti-aging effect, can be used for preparing the health-care food having anti-aging efficacies. 5. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 4, characterized in that, with ginseng or tuber fleeceflower root as raw material, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide is 1:4-9:1, with ginseng and tuber fleeceflower root as raw material, the mass ratio of ginseng and tuber fleeceflower root is 1:4-9:1. 6. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 5, characterized in that, with ginseng or tuber fleeceflower root as raw material, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide is 2:3-2:1, with ginseng and tuber fleeceflower root as raw material, the mass ratio of ginseng and tuber fleeceflower root is 2:3-2:1. 7. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 4, characterized in that, during water extraction, the mass volume ratio of ginseng and/or tuber fleeceflower root medicinal material with water is 1:2-1:20, the extraction temperature is 50-100° C., the extraction duration is 1-10 h; during concentration, the concentration temperature is 40-100° C.; during alcohol precipitation, the volume ratio of ethanol and concentrated liquid is 2:1-9:1. 8. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 4, characterized in that, ginseng refers to the medicinal root part of ginseng, tuber fleeceflower root refers to the medicinal tuber root part of tuber fleeceflower root. 9. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 1, characterized in that, the anti-aging efficacies refers to the prolongation of life span of organisms under stress factors in vivo and in vitro and the relief of symptoms induced by these stress factors. 10. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 1, characterized in that, the dosage form of health-care food is capsule, powder, granule, tablet or oral liquid. 11. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to anyone of claims 2, characterized in that, the ginseng and tuber fleeceflower root complex polysaccharide is prepared by the following method: with ginseng or tuber fleeceflower root as raw material, ginseng polysaccharide or tuber fleeceflower root polysaccharide is prepared by processes including water extraction, concentration and alcohol precipitation, then these two polysaccharides are mixed in a stoichiometric ratio, to prepare the ginseng and tuber fleeceflower root complex polysaccharide, or the ginseng and tuber fleeceflower root complex polysaccharide is prepared by the following method: with ginseng and tuber fleeceflower root as raw material, ginseng polysaccharide or tuber fleeceflower root polysaccharide is prepared by processes including water extraction, concentration and alcohol precipitation; the complex polysaccharide has an anti-aging effect, can be used for preparing the health-care food having anti-aging efficacies. 12. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to anyone of claims 3, characterized in that, the ginseng and tuber fleeceflower root complex polysaccharide is prepared by the following method: with ginseng or tuber fleeceflower root as raw material, ginseng polysaccharide or tuber fleeceflower root polysaccharide is prepared by processes including water extraction, concentration and alcohol precipitation, then these two polysaccharides are mixed in a stoichiometric ratio, to prepare the ginseng and tuber fleeceflower root complex polysaccharide, or the ginseng and tuber fleeceflower root complex polysaccharide is prepared by the following method: with ginseng and tuber fleeceflower root as raw material, ginseng polysaccharide or tuber fleeceflower root polysaccharide is prepared by processes including water extraction, concentration and alcohol precipitation; the complex polysaccharide has an anti-aging effect, can be used for preparing the health-care food having anti-aging efficacies. 13. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 11, characterized in that, with ginseng or tuber fleeceflower root as raw material, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide is 1:4-9:1, with ginseng and tuber fleeceflower root as raw material, the mass ratio of ginseng and tuber fleeceflower root is 1:4-9:1. 14. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 12, characterized in that, with ginseng or tuber fleeceflower root as raw material, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide is 1:4-9:1, with ginseng and tuber fleeceflower root as raw material, the mass ratio of ginseng and tuber fleeceflower root is 1:4-9:1. 15. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 13, characterized in that, with ginseng or tuber fleeceflower root as raw material, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide is 2:3-2:1, with ginseng and tuber fleeceflower root as raw material, the mass ratio of ginseng and tuber fleeceflower root is 2:3-2:1. 16. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 14, characterized in that, with ginseng or tuber fleeceflower root as raw material, the mass ratio of ginseng polysaccharide and tuber fleeceflower root polysaccharide is 2:3-2:1, with ginseng and tuber fleeceflower root as raw material, the mass ratio of ginseng and tuber fleeceflower root is 2:3-2:1. 17. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 11, characterized in that, during water extraction, the mass volume ratio of ginseng and/or tuber fleeceflower root medicinal material with water is 1:2-1:20, the extraction temperature is 50-100° C., the extraction duration is 1-10 h; during concentration, the concentration temperature is 40-100° C.; during alcohol precipitation, the volume ratio of ethanol and concentrated liquid is 2:1-9:1. 18. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 12, characterized in that, during water extraction, the mass volume ratio of ginseng and/or tuber fleeceflower root medicinal material with water is 1:2-1:20, the extraction temperature is 50-100° C., the extraction duration is 1-10 h; during concentration, the concentration temperature is 40-100° C.; during alcohol precipitation, the volume ratio of ethanol and concentrated liquid is 2:1-9:1. 19. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 11, characterized in that, ginseng refers to the medicinal root part of ginseng, tuber fleeceflower root refers to the medicinal tuber root part of tuber fleeceflower root. 20. The use of ginseng and tuber fleeceflower root complex polysaccharide in the preparation of health-care food having anti-aging efficacies according to claim 12, characterized in that, ginseng refers to the medicinal root part of ginseng, tuber fleeceflower root refers to the medicinal tuber root part of tuber fleeceflower root.
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