LIPOSOMAL NUTRACEUTICAL COMPOSITIONS AND METHODS OF MAKING THE SAME
원문보기
IPC분류정보
국가/구분
United States(US) Patent
공개
국제특허분류(IPC7판)
A61K-031/05
A61K-009/127
A61K-036/752
A61K-036/53
A61K-047/10
A61K-047/44
A61K-038/48
A23L-033/105
출원번호
16937545
(2020-07-23)
공개번호
20210023023
(2021-01-28)
발명자
/ 주소
Gibbs, Tracy
출원인 / 주소
Gibbs, Tracy
인용정보
피인용 횟수 :
0인용 특허 :
0
초록▼
Disclosed are liposomal supplement compositions and methods of formulating the same. A liposomal composition includes a nutraceutical compound such as cannabidiol (CBD), a proteolytic enzyme component such as papain and/or bromelain, and a phytochemical component such as piceatannol. These component
Disclosed are liposomal supplement compositions and methods of formulating the same. A liposomal composition includes a nutraceutical compound such as cannabidiol (CBD), a proteolytic enzyme component such as papain and/or bromelain, and a phytochemical component such as piceatannol. These components are encapsulated within liposomes for enhanced bioavailability and effectiveness.
대표청구항▼
1. A method of forming a liposomal composition comprising liposomes and a target compound encapsulated by the liposomes, the method comprising: mixing oil-soluble ingredients and a liposome subunit component into an oil carrier;homogenizing the oil-soluble ingredients, liposome subunit component, an
1. A method of forming a liposomal composition comprising liposomes and a target compound encapsulated by the liposomes, the method comprising: mixing oil-soluble ingredients and a liposome subunit component into an oil carrier;homogenizing the oil-soluble ingredients, liposome subunit component, and the oil carrier to form an oil-based suspension;mixing water-soluble ingredients and a surfactant into an aqueous carrier;mixing the water-soluble ingredients with the surfactant and the aqueous carrier to form an aqueous suspension;mixing the homogenized oil-based suspension with the homogenized aqueous suspension to form a dual suspension comprising a suspension of liposomal oil droplets and a suspension of droplets containing the target compound; andcooling the suspension to allow liposomes to encapsulate the target compound and form the liposomal composition. 2. The method of claim 1, wherein the method omits the addition of polyethylene glycol (PEG). 3. The method of claim 1, wherein the method omits the addition of alcohol. 4. The method of claim 1, wherein the oil carrier includes medium chain triglyceride (MCT) oil. 5. The method of claim 1, wherein the oil-soluble ingredients comprise one or more plant essential oils as a preservative. 6. The method of claim 5, wherein the preservatives include citrus oil, oregano oil, or both. 7. The method of claim 1, wherein the liposome subunit component includes phosphatidylcholine. 8. The method of claim 1, wherein the surfactant includes a polyethoxylated oil. 9. The method of claim 1, wherein cooling is carried out for about 12 to about 36 hours. 10. The method of claim 1, further comprising a step of adjusting the pH of the liposomal composition so that the pH is greater than 4.8. 11. The method of claim 1, wherein the liposomes have an average particle size of about 200 nm to about 450 nm. 12. The method of claim 1, wherein the liposomes are formed with an encapsulation efficiency of 60% or higher. 13. The method of claim 1, wherein the target compound is a cannabinoid. 14. The method of claim 13, wherein the cannabinoid is cannabidiol (CBD). 15. A liposomal composition, comprising: a nutraceutical compound;a proteolytic enzyme component;a phytochemical component; anda plurality of liposomes encapsulating the nutraceutical compound, proteolytic enzyme component, and phytochemical component. 16. The liposomal composition of claim 15, wherein the nutraceutical compound is CBD. 17. The liposomal composition of claim 15, wherein the proteolytic enzyme component includes one or both of papain or bromelain. 18. The liposomal composition of claim 15, wherein the phytochemical component includes piceatannol. 19. The liposomal composition of claim 15, further comprising one or both of citrus oil or oregano oil. 20. A liposomal composition, comprising: cannabidiol;a proteolytic enzyme component comprising one or both of papain or bromelain;a phytochemical component comprising piceatannol; anda plurality of liposomes encapsulating the cannabidiol, proteolytic enzyme component, and phytochemical component.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.