3D PRINTING SYSTEM FOR MANUFACTURING ARTIFICIAL BLOOD VESSEL AND METHOD FOR MANUFACTURING ARTIFICIAL BLOOD VESSEL USING SAME
원문보기
IPC분류정보
국가/구분
United States(US) Patent
공개
국제특허분류(IPC7판)
B29C-064/40
A61F-002/06
B29C-064/209
B29C-064/106
B33Y-010/00
B33Y-030/00
B33Y-070/00
B33Y-080/00
출원번호
17059401
(2019-12-17)
공개번호
20210379835
(2021-12-09)
우선권정보
KR-10-2019-0153497 (2019-11-26)
국제출원번호
PCT/KR2019/017877
(2019-12-17)
발명자
/ 주소
AHN, Geun Seon
KIM, Min Kyung
MIN, Kyung Hyun
LEE, In Gyu
출원인 / 주소
AHN, Geun Seon
인용정보
피인용 횟수 :
0인용 특허 :
0
초록▼
The present invention relates to a three-dimensional (3D) printing system for manufacturing an artificial blood vessel and a method for manufacturing an artificial blood vessel using the same, wherein a cylindrical support having a hollow 3D porous structure including a thermoplastic polymer is manu
The present invention relates to a three-dimensional (3D) printing system for manufacturing an artificial blood vessel and a method for manufacturing an artificial blood vessel using the same, wherein a cylindrical support having a hollow 3D porous structure including a thermoplastic polymer is manufactured and vertically fixed, and a hydrogel divided into at least two sections is discharged into the support, thereby maintaining the structure and shape constantly even after printing and manufacturing an artificial blood vessel having a hollow multilayered structure. The 3D printing system for manufacturing an artificial blood vessel comprises: a rotatable support manufacturing unit which forms a hollow cylindrical support having a 3D porous structure by discharging a polymer to the outer circumference thereof through a first head; a first head which forms a hollow cylindrical support having a 3D porous structure by discharging a polymer to the support manufacturing unit; a support vertically holding the hollow cylindrical support manufactured through the first head; and a second head which discharges a hydrogel, divided into at least two sections, into the cylindrical support vertically held and fixed to the support.
대표청구항▼
1. A 3D printing system for manufacturing an artificial blood vessel comprising: a support manufacturing unit which is rotatable and forms a hollow cylindrical support of a 3D porous structure when polymer is discharged to the outer circumferential surface through a first head;a first head forming t
1. A 3D printing system for manufacturing an artificial blood vessel comprising: a support manufacturing unit which is rotatable and forms a hollow cylindrical support of a 3D porous structure when polymer is discharged to the outer circumferential surface through a first head;a first head forming the hollow cylindrical support of the 3D porous structure by discharging polymer to a support manufacturing unit;a holder for vertically holding the cylindrical support manufactured through the first head; anda second head for discharging hydrogel, which is divided into at least two sections, into the cylindrical support vertically held and fixed on the holder. 2. The 3D printing system according to claim 1, wherein the first head comprises: a first pneumatic cylinder ascending and descending to discharge the polymer; a first discharge unit for discharging the polymer by lowering of the first pneumatic cylinder; and a temperature control unit for controlling temperature of the discharged polymer. 3. The 3D printing system according to claim 1, wherein the second head comprises: a second pneumatic cylinder ascending and descending to discharge the polymer; a second discharge unit for discharging the hydrogel divided into at least two sections by lowering of the second pneumatic cylinder; and a temperature control unit for controlling temperature of the discharged hydrogel divided into at least two sections. 4. The 3D printing system according to claim 1, wherein the support manufacturing unit comprises: a rotary shaft which is rotatable when the polymer is discharged; a motor connected to the one side of the rotary shaft to rotate the rotary shaft; and a bearing connected to the other side of the rotary shaft to support the rotary shaft. 5. The 3D printing system according to claim 1, wherein the second head discharges the hydrogel divided into at least two sections into the cylindrical support vertically fixed on the holder. 6. The 3D printing system according to claim 1, wherein the holder is movable in a vertical direction while the fixed second head discharges the hydrogel divided into at least two sections. 7. The 3D printing system according to claim 1, wherein the polymer is thermoplastic polymer. 8. The 3D printing system according to claim 7, wherein the thermoplastic polymer is at least one selected from groups including lactide, caprolactone, glycolide, dioxanone, propylene, ethylene, vinylchloride, butadiene, methyl methacrylate, acrylic acid, 2-hydroxyethylmethacrylate, carbonate, and polyethylene terephalate. 9. The 3D printing system according to claim 1, wherein the hydrogel divided into at least two sections contains at least one selected from groups including polymer gels, cells, growth factors, and extracellular matrix, and a cross section of the hydrogel divided into the at least two sections discharged into the support and a cross section of the hydrogel divided into the at least two sections charged in the second pneumatic cylinder have the same pattern. 10. A method for manufacturing an artificial blood vessel comprising the steps of: forming a hollow cylindrical support of a 3D porous structure by discharging polymer to the outer circumferential surface of a support manufacturing unit through a first head;vertically fixing the cylindrical support; anddischarging hydrogel, which is divided into at least two sections, into the support while vertically moving a second head. 11. The method according to claim 10, wherein the step of forming the support comprises the steps of: moving the first head above the support manufacturing unit; rotating the support manufacturing unit after locating the first head above the support manufacturing unit; and discharging the polymer to the outer circumferential surface of the support manufacturing unit while moving the first head in a longitudinal direction of the support manufacturing unit. 12. The method according to claim 11, wherein the rotating step and the discharging step are performed at the same time or performed in consecutive order. 13. The method according to claim 10, further comprising the step of removing a part of the hydrogel divided into at least two sections discharged into the support after the discharging step. 14. A support fixing device for 3D printing comprising: a support plate on which a hollow cylindrical support is located; andan internal fixing part formed in the middle of the support plate,wherein the internal fixing part gets in contact with the inner circumferential surface of the support vertically located on the support plate in order to fix the support on the support plate. 15. The support fixing device according to claim 14, wherein the internal fixing part comprises: a tap hole disposed in the middle of the support plate; a bolt coupled with the tap hole; and an elastic tube disposed on the outer circumferential surface of the bolt. 16. The support fixing device according to claim 15, wherein the diameter of the bolt is smaller than the inner diameter of the support. 17. The support fixing device according to claim 15, wherein the elastic tube is an elastic body which is expandable in a radial direction when pressure is vertically applied by the bolt. 18. The support fixing device according to claim 14, further comprising an external fixing part formed on the upper surface of the support plate,wherein the external fixing part gets in contact with the outer circumferential surface of the support to fix the support. 19. The support fixing device according to claim 18, wherein the external fixing part comprises:a first fixing plate formed at one end of the upper surface of the support plate;a second fixing plate formed at the other end of the upper surface of the support plate;a guide for connecting the first fixing plate and the second fixing plate with each other; anda contact part which is movable along the guide. 20. The support fixing device according to claim 19, wherein the contact part includes a contact groove formed in the surface coming into contact with the outer circumferential surface of the support. 21. (canceled)
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