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A pullulan copolymer obtained by reacting with a polymerizable olefinic compound a pullulan ester which is produced by reacting pullulan with an unsaturated acid to introduce a double bond of carbon thereinto. It is highly hydrophilic and is a material having a high affinity for a living body and wh

A pullulan copolymer obtained by reacting with a polymerizable olefinic compound a pullulan ester which is produced by reacting pullulan with an unsaturated acid to introduce a double bond of carbon thereinto. It is highly hydrophilic and is a material having a high affinity for a living body and which is, therefore, useful for making contact lenses, intraocular lenses, artificial bones and blood vessels, etc.

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A pullulan copolymer obtained by reacting pullulan with an unsaturated acid of the formula HOOCR10 or the anhydride thereof in which R10 is an unsaturated hydrocarbon group having a carbon-carbon double bond and 2 to 16 carbon atoms, in the presence of a saturated acid of the formula HOOCR11 in whic

A pullulan copolymer obtained by reacting pullulan with an unsaturated acid of the formula HOOCR10 or the anhydride thereof in which R10 is an unsaturated hydrocarbon group having a carbon-carbon double bond and 2 to 16 carbon atoms, in the presence of a saturated acid of the formula HOOCR11 in which R11 is an alkyl group having 2 to 16 carbon atoms and an acid catalyst to produce a pullulan olefin ester of formula (A): [C6H7O2(OH)3-a-b(OX)a(OY)b]mH2O (A) where X is －C(〓O)R1 and R1 is an unsaturated hydrocarbon group derived from an unsaturated acid and having a carbon-carbon double bond and 2 to 16 carbon atoms, Y is －C(〓O)R2 and R2 is an alkyl group having 1 to 14 carbon atoms, m is a natural number of at least 5, and a and b each is a natural number defined by a+b≤3 and copolymerizing said pullulan olefinic ester with an olefinic compound polymerizable to form a recurring unit of formula (B): [C(R3)R4－C(R5)R6]n(B) where R3, R4 and R5 are each selected from hydrogen and CH3; R6 is selected from －C(〓O)OR7, －C(〓O)CN, －OH, acyloxy, phenyl, pyridine, tolyl, pyrrolidone, lower alkyl and substituted pyrrolidone groups, R7 being selected from an alkyl group having 1 to 12 carbon atoms, a cyclohexyl group, a hydroxyalkyl group having 1 to 4 carbon atoms, an aminoalkyl group having 1 to 8 carbon atoms, a dialkyl aminoalkyl group having 1 to 8 carbon atoms, a glycidyl group, a tetrahydrofuran group, a lower alkyl substituted tetrahydrofuran group having 1 to 4 carbon atoms, a benzyl group, a polyethylene oxide group having a polymerization degree of 2 to 11 and an imino group; and n is a natural number of 20 to 300,000.