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[미국특허] Human hyaluronidase 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-009/26
  • C12N-015/11
  • C12N-015/63
  • C12N-015/85
출원번호 US-0675507 (1996-07-03)
발명자 / 주소
  • Au-Young Janice
  • Hawkins Phillip R.
  • Hillman Jennifer L.
출원인 / 주소
  • Inctye Pharmaceuticals, Inc.
대리인 / 주소
    Incyte PharmaceuticalsBillings
인용정보 피인용 횟수 : 24  인용 특허 : 0

초록

The present invention provides a polynucleotide (hhp) which identifies and encodes a novel human hyaluronidase (HHP). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding HHP, and a method for making HHP with the host cells

대표청구항

[ We claim:] [5.] A method of producing a polypeptide consisting of the amino acid sequence shown in SEQ ID NO: 1, the method comprising the steps of:a) culturing the host cell of claim 4 to allow the expression of the polypeptide; andb) recovering the polypeptide from the host cell culture.

이 특허를 인용한 특허 (24)

  1. Wei, Ge; Selvam, Krishnasamy Panneer; Bookbinder, Louis; Frost, Gregory I., Extended soluble PH20 polypeptides and uses thereof.
  2. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Hyaluronidase and factor VIII compositions.
  3. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Methods for reducing intraocular pressure by administering a soluble hyaluronidase glycoprotein (sHASEGP).
  4. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Methods for treating a disease characterized by an excess of hyaluronan by administering a soluble hyaluronidase glycoprotein (sHASEGP).
  5. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Methods for treating edema by administering a Soluble Hyaluronidase Glycoprotein (sHASEGP).
  6. Wei, Ge; Selvam, Krishnasamy Panneer; Bookbinder, Louis; Frost, Gregory I., Neutral active soluble truncated PH20 polypeptides and uses thereof.
  7. Wei, Ge; Shepard, H. Michael; Zhao, Qiping; Connor, Robert James, PH20 polypeptide variants, formulations and uses thereof.
  8. Claudine Bruck BE; Teresa Cabezon Silva BE; Anne-Marie Eva Fernande Delisse BE; Catherine Marie Ghislaine Gerard BE; Angela Lombardo-Bencheikh BE, Recombinant papillomavirus vaccine and method for production and treatment.
  9. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  10. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  11. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  12. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  13. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  14. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  15. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  16. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases.
  17. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  18. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  19. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  20. Bookbinder, Louis H.; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  21. Bookbinder, Louis H.; Kundu, Anirbau; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  22. Bookbinder, Louis; Kundu, Anirban; Frost, Gregory I., Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof.
  23. Teschner, Wolfgang; Svatos, Sonja; Bruckschwaiger, Leopold; Weber, Alfred; Schwarz, Hans-Peter; Lei, Laura, Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof.
  24. Frost, Gregory I.; Bilinsky, Igor; Vaughn, Daniel; Sugarman, Barry, Super fast-acting insulin compositions.
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