초록 ▼

Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect

Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect the physiological parameter difference, such as oxygen levels, in the left atrium. The sensor can be carried by the needle, at its tip or along its body, and can measure the physiological parameter levels contained in the blood, fluid, or tissue.

대표청구항 ▼

What is claimed is: 1. A method of locating a tissue region of interest for passage of an apparatus therethrough, comprising: advancing the probe to a tissue region of interest within a mammalian heart; after advancing the probe to the tissue region of interest, probing an area of tissue with a pro

What is claimed is: 1. A method of locating a tissue region of interest for passage of an apparatus therethrough, comprising: advancing the probe to a tissue region of interest within a mammalian heart; after advancing the probe to the tissue region of interest, probing an area of tissue with a probe comprising a needle having a sensing element disposed at a distal end thereof, said probing comprising inserting the sensing element at least partially into the tissue region; sensing a physiological parameter of the tissue while probing the area; and completely piercing the tissue with the probe upon detecting a change in the sensed physiological parameter. 2. The method of claim 1 further comprising advancing the probe into a right atrial chamber of a heart prior to probing an area. 3. The method of claim 1 wherein probing an area of tissue comprises probing the tissue in a predetermined pattern. 4. The method of claim 1 wherein probing an area of tissue comprises probing an atrial septum. 5. The method of claim 1 wherein sensing a physiological parameter comprises sensing the parameter selected from the group consisting of oxygen saturation, temperature, carbon dioxide concentration, blood pressure, blood velocity, pH, and combinations thereof. 6. The method of claim 1 wherein sensing a physiological parameter comprises transmitting a light and measuring its reflectance as being indicative of the physiological parameter. 7. The method of claim 1 wherein sensing a physiological parameter comprises comparing a measurement from the probed area to a measurement from an area proximal of the probed area. 8. The method of claim 1 wherein piercing the tissue comprises advancing the probe into a left atrial chamber. 9. The method of claim 1, wherein the needle comprises a beveled needle sized within the range of 20-27 gauge. 10. The method of claim 1, wherein the probe is robotically guided. 11. A method of locating a tissue region of interest for passage of an apparatus therethrough, comprising: probing an area of tissue with a probe comprising a needle having a sensing element disposed at a distal end thereof, said probing comprising inserting the sensing element at least partially into the tissue region; sensing a physiological parameter of the tissue while probing the area; completely piercing the tissue with the probe upon detecting a change in the sensed physiological parameter; and advancing a catheter over a guidewire towards the tissue region of interest, the guidewire being attached to a proximal end of the probe. 12. A method of locating a tissue region of interest for passage of an apparatus therethrough, comprising: probing an area of tissue with a probe comprising a needle having a sensing element disposed at a distal end thereof, said probing comprising inserting the sensing element at least partially into the tissue region; sensing a physiological parameter of the tissue while probing the area; and completely piercing the tissue with the probe upon detecting a change in the sensed physiological parameter, wherein sensing a physiological parameter comprises comparing a measurement from a left atrial chamber to a measurement from a right atrial chamber. 13. A method of locating a tissue region of interest for passage of an apparatus therethrough, comprising: probing an area of tissue with a probe comprising a needle having a sensing element disposed at a distal end thereof, said probing comprising inserting the sensing element at least partially into the tissue region; sensing a physiological parameter of the tissue while probing the area; and completely piercing the tissue with the probe upon detecting a change in the sensed physiological parameter, wherein the probe is robotically guided with a raster scan.