초록 ▼

The present invention relates to an automated solution preparation apparatus having containers for holding solid reagents, a dispensing mechanism for dispensing the reagents to a balance, a supply for providing liquid to rinse the reagents from the balance into a chamber where additional liquids can

The present invention relates to an automated solution preparation apparatus having containers for holding solid reagents, a dispensing mechanism for dispensing the reagents to a balance, a supply for providing liquid to rinse the reagents from the balance into a chamber where additional liquids can be added, and a manifold connected to the chamber for dispensing the solution into receptacles. The chamber can have probes for monitoring properties of the solution, and heating and cooling jackets for adjusting the solution temperature. The present invention also relates to a method for using the automated solution preparation apparatus to prepare solutions of different concentrations and properties by dispensing reagents from containers into a weighing zone, where each reagent is separately weighed and rinsed from the weighing zone into a chamber, diluting the reagents with additional liquid solvent to prepare the solution and discharging the solution from the chamber into receptacles.

대표청구항 ▼

1. A solution preparation apparatus, the apparatus comprising: a plurality of containers for holding reagents;a dispensing mechanism in flow communication and operatively associated with each container that selectively and sequentially dispenses an amount of one or more reagents;a balance that seque

1. A solution preparation apparatus, the apparatus comprising: a plurality of containers for holding reagents;a dispensing mechanism in flow communication and operatively associated with each container that selectively and sequentially dispenses an amount of one or more reagents;a balance that sequentially receives the dispensed reagent(s) and weighs in a cumulative way each received reagent;a mixing chamber that receives the concentrated solution and additional liquids to adjust and prepare a liquid mixture of a predetermined concentration, wherein the mixing chamber has a chamber wall; anda supply that provides liquid to the balance for removing the reagents from the balance and forms a concentrated solution. 2. The apparatus of claim 1, which further comprises: a solution distributor in fluid communication with the chamber that conveys the discharged solution into receptacles. 3. The apparatus of claim 2, which further comprises: a processor for controlling the dispensing, weighing, mixing, adjusting and discharging processes. 4. The apparatus of claim 1, which further comprises: one or more liquid reagent dispensers that can provide one or more liquid reagents to the chamber. 5. The apparatus of claim 4, wherein the liquid reagents can be acids, bases, buffers or detergents or solutions of acids, bases, buffers or detergents. 6. The apparatus of claim 1, which further comprises: a volume detector in operative association with the chamber for determining the volume of solution within the chamber. 7. The apparatus of claim 6, wherein the volume detector comprises: an infrared light source;a floating disc; anda detector in operative association with the light source and floating disc, that measures the liquid level in the chamber. 8. The apparatus of claim 1, wherein chamber wall is insulated for maintaining the chamber at a consistent temperature. 9. The apparatus of claim 8, which further comprises: heating and cooling jackets within the chamber wall that facilitates adjusting the temperature of the chamber and solution. 10. The apparatus of claim 2, wherein the solution distributor further comprises: a sterilizer tank for eliminating biological organisms and contaminants and a manifold, wherein the sterilization tank is located in between and in liquid communication with the chamber and the manifold. 11. The apparatus of claim 2, which further comprises: filters for removing particulates from the solution before dispensing the solution into receptacles, wherein the filters are located in and in fluid communication with the solution distributor. 12. The apparatus of claim 1, wherein the reagents are solid reagents. 13. A solution preparation apparatus, the apparatus comprising: a plurality of containers for holding reagents;a dispensing mechanism in flow communication and operatively associated with each container that selectively and sequentially in a cumulative way dispenses an amount of one or more reagents;a balance, wherein the balance has a balance plate suitably dimensioned for receiving and suitably dimensioned for weighing in a cumulative way a plurality of sequentially dispensed reagents at the same time without loss of any reagent from the balance plate;a mixing chamber that receives the concentrated solution and additional liquids to adjust and prepare a liquid mixture of a predetermined concentration, wherein the mixing chamber has a chamber wall; anda supply that provides liquid to the balance for removing the reagents from the balance and forms a concentrated solution. 14. The apparatus of claim 1, further comprising probes associated with the mixing chamber for monitoring chemical and physical properties of the solution. 15. The apparatus of claim 1, which further comprises: a plurality of separate compartments, wherein each separate compartment houses a different section of the apparatus, and wherein the compartments can be scaled from the outside atmosphere by one or more airtight doors. 16. A solution preparation apparatus, the apparatus comprising: a plurality of containers for holding canisters;a plurality of conduits, wherein a single conduit is connected to and in flow communication with an egress end of one of the plurality of containers;one or more canisters containing solid reagents placed within a respective container, and connected to the egress end of the container so as to form an airtight seal between the canister and the conduit;a dispensing mechanism comprising: a plurality of valves connected to and in flow communication with the plurality of conduits; anda dispenser block supporting the valves and conduits, such that the dispensing mechanism is operatively associated with each container that selectively and sequentially dispenses an amount of one or more reagents;a balance comprising: one or more balance plate(s) that sequentially receives the dispensed reagent(s) from an egress end of each of the plurality of conduits, and weighs each received reagent;a supply that provides liquid to the balance for removing the reagents from the balance and forms a concentrated solution;a chamber that receives the solution of solid reagents and liquid from the balance;a volume setting system that determines the volume of solution within the chamber;a pump that delivers liquid to the chamber until the volume setting system indicates the solution has reached a predetermined amount; anda valve that releases the solution from the solution into a manifold that dispenses the released solution into one or more receptacles. 17. A method of preparing solutions which comprises: providing a plurality of reagents;selectively and sequentially dispensing reagent(s) from reagent containers into a weighing zone, wherein the amounts of the one or more reagents dispensed into the weighing zone are each individually controlled by a computer actuated valve;receiving the reagents selectively and sequentially in the weighing zone, wherein each dispensed reagent is separately weighed;providing a liquid solvent;spraying the liquid solvent into the weighing zone for rinsing the dispensed reagents from the weighing zone;rinsing the one or more dispensed reagents from the weighing zone into a chamber with the spray of liquid solvent and forming a concentrated solution;receiving the concentrated solution from the weighing zone in the chamber;providing a liquid solvent to the chamber to dilute the concentrated solution;diluting the concentrated solution from the weighing zone with additional liquid solvent to prepare a solution of predetermined concentration; anddischarging the solution of predetermined concentration from the chamber to one or more solution receptacles. 18. The method of claim 17, further comprising: providing one or more liquid reagents;injecting one or more of the liquid reagents into the concentrated solution received in the chamber, wherein the liquid reagents adjust one or more properties of the concentrated solution; andrecording the chemical and physical properties of the solution. 19. The method of claim 18, wherein the properties adjusted by injection of a liquid reagent includes pH. 20. A non-transitory computer-readable medium that stores computer-readable instructions for execution by a processing system, the computer readable instructions for preparing solutions comprising: instructions to activate a valve for selectively and sequentially dispense reagent(s) from reagent containers into a weighing zone;instructions to separately weigh each of the selectively and sequentially dispense reagent(s);instructions to activate a pump for providing one or more liquid reagents for rinsing the one or more dispensed reagents from the weighing zone into a chamber;instructions to activate a pump for providing a liquid solvent to the chamber to dilute the concentrated solution; andinstructions to open a valve for discharging the solution of predetermined concentration from the chamber to one or more solution receptacles. 21. A solution preparation apparatus, the apparatus comprising: a plurality of containers for holding reagents;a dispensing mechanism in flow communication and operatively associated with each container that selectively and sequentially dispenses an amount of one or more reagents, wherein the reagents can be acids, bases, buffers or detergents or solutions of acids, bases, buffers or detergents or solid reagents;a balance, wherein the balance has a balance plate suitably dimensioned for receiving and suitably dimensioned for weighing in a cumulative way a plurality of sequentially dispensed reagents at the same time without loss of any reagent from the balance plate;a mixing chamber that receives the concentrated solution and additional liquids from the balance to adjust and prepare a liquid mixture of a predetermined concentration, wherein the mixing chamber has a chamber wall;a probe associated with the mixing chamber for monitoring the chemical and physical properties of the solution;a pump that delivers liquid to the chamber until the volume setting system indicates the solution has reached a predetermined amount;a valve that releases the solution from the solution into a manifold that dispenses the released solution into one or more receptacles; anda plurality of filters for removing particulates from the solution before discharging the solution into one or more receptacles, wherein the filters are located in and in fluid communication with a solution distributor. 22. The apparatus of claim 21, wherein the solid reagent comprises a powder, crystal, pellet, grain, flake, filing, shaving or dust or any combination thereof. 23. The apparatus of claim 21, wherein the solid reagent comprises a pharmaceutical preparation. 24. The apparatus of claim 21, which further comprises: heating and cooling jackets within the chamber wall that facilitates adjusting the temperature of the chamber and solution.