초록 ▼

Ⅳ. 연구개발결과
레스베라트롤 생산벼 익산 526의 안전성을 확인하고 이벤트 Agb0102로 명명하였다. 비의도적 혼입 염기서열 확인 및 복수세대의 유전분석 등 재료평가와 잡초화 가능성,토양 및 타생물에 대한 영향 등 환경위해성평가, 영양성분, 알레지 및 독성 등 식품안전성평가 결과 Agb0102의 안전성을 확인하였다. 레스베라트롤 벼 실용화를 위한 Agb0102 안전성 심사자료 작성하고, 안전성평가 항목별로 study reports 33건을 작성하였다. 레스베라트롤 생산벼 익산 526의 조직배양을 통한 산업화를 위해 기내배양

Ⅳ. 연구개발결과
레스베라트롤 생산벼 익산 526의 안전성을 확인하고 이벤트 Agb0102로 명명하였다. 비의도적 혼입 염기서열 확인 및 복수세대의 유전분석 등 재료평가와 잡초화 가능성,토양 및 타생물에 대한 영향 등 환경위해성평가, 영양성분, 알레지 및 독성 등 식품안전성평가 결과 Agb0102의 안전성을 확인하였다. 레스베라트롤 벼 실용화를 위한 Agb0102 안전성 심사자료 작성하고, 안전성평가 항목별로 study reports 33건을 작성하였다. 레스베라트롤 생산벼 익산 526의 조직배양을 통한 산업화를 위해 기내배양 줄기세포의 항산화효과, 주름개선효과 등 기능성도 확인하고 대량생산체계를 확립하였다

Abstract ▼

The transgenic resveratrol rice line of Iksan526, which developed by NICS, RDA, was generated by expressing resveratrol synthase(RS) gene and selectable marker basta gene into commercial variety ‘Dongjin’ under control of maize ubiquitin promoter. This study was conducted to assess the otential ris

The transgenic resveratrol rice line of Iksan526, which developed by NICS, RDA, was generated by expressing resveratrol synthase(RS) gene and selectable marker basta gene into commercial variety ‘Dongjin’ under control of maize ubiquitin promoter. This study was conducted to assess the otential risks of resveratrol rice Iksan526 on human health including the molecular characterization of Resveratrol synthase(RS) protein and the nutrients such as proximates, amino acids, fatty acids, minerals, and vitamins, and also to assess the possible impact on environment such as insects, pathogens, bioindicators, the soil microbial community and the out-crossing rate to cultivated rice. From these results, resveratrol rice Iksan526 was designated of Event Agb0102. The documentation of biosafety assessment including 33th of study reports was draw up, and should be compensated and submitted to KFDA(The Korea Food and Drug Administration.
Resveratrol is a polyphenolic compound found in various natural products such as grapes and berries and possesses anti-cancer, anti-hyperlipidemia, and anti-aging properties. To commercialize the approving Event Agb0102, callus were induced from resveratrol-enriched rice to test effectiveness as nutraceutical and cosmeceutical materials. In vitro tests show that the callus have antioxidant, anti-melanogenic, anti-wrinkle activities. This study suggests that the callus from resveratrol-enriched rice may be a promising candidate highly functional materials for cosmeceutics.