초록 ▼

본 연구는 유치와 영구치의 치수절단술 치료가 필요한 치아를 가진 환자를 대상으로 외국산 대조군(ProrootMTA) 과 국산 시험군(OrthoMTA, RetroMTA)를 무작위 배정하여 치료하고 6-12개월 동안 방사선 및 임상관찰을 시행하여 동등성을 통계적 방법으로 비교 검증하고자 하였음.
총 임상참여 치아는 255개 [151개 (유치)+ 104개 (영구치)]였으며 유치의 경우 연구에 참여한 총 151개 치아 중 109개 치아가 12개월 까지 추적 관찰되었으며 ProRootMTA?, OrthoMTA? RetroMTA?그룹의

본 연구는 유치와 영구치의 치수절단술 치료가 필요한 치아를 가진 환자를 대상으로 외국산 대조군(ProrootMTA) 과 국산 시험군(OrthoMTA, RetroMTA)를 무작위 배정하여 치료하고 6-12개월 동안 방사선 및 임상관찰을 시행하여 동등성을 통계적 방법으로 비교 검증하고자 하였음.
총 임상참여 치아는 255개 [151개 (유치)+ 104개 (영구치)]였으며 유치의 경우 연구에 참여한 총 151개 치아 중 109개 치아가 12개월 까지 추적 관찰되었으며 ProRootMTA?, OrthoMTA? RetroMTA?그룹의 방사선학적 성공률은 각각 100%, 94.7%, 94.7% 였으며 임상적인 성공률은 100%, 97.4%, 100% 였음. 영구치의 경우도 연구에 참여한 104개의 치아 중 76개 치아가 12개월까지 추적 관찰되었으며 ProRootMTA?, OrthoMTA? RetroMTA?그룹에서 각각 96, 92.3, 96%의 임상적 성공을 보임. 세 가지 재료에 따른 유치와 영구치의 치수절단술의 성공률은 유의한 차이를 보이지 않았음.
상기 연구결과는 SCI 논문에 1편 게재 및 1편 투고중에 있음.

Abstract ▼

Ⅰ. The Purpose
The MTA a spotlighted material for pulpotomy treatment in primary and permanent teeth, has been widely used after the US Company Dentsply crafted the ProRootMTA. Recently, the Korean Company BioMTA produced the OrthoMTA and RetroMTA which have complemented drawback of the ProRootMT

Ⅰ. The Purpose
The MTA a spotlighted material for pulpotomy treatment in primary and permanent teeth, has been widely used after the US Company Dentsply crafted the ProRootMTA. Recently, the Korean Company BioMTA produced the OrthoMTA and RetroMTA which have complemented drawback of the ProRootMTA. We would like to compare the safety and the efficacy of the new coming MTA with the ProRootMTA in primary and permanent teeth
Ⅱ. The Contents and Ranges of this research
This research was exercised based upon patients who visited the Yonsei University Dental Hospital for pulpotomy treatment and randomly applied the ProrootMTA, OrthoMTA and RetroMTA. Due to clinical and radiographic follow-up examinations after 6~12months postoperation equivalence was compared through statistical methodology.
1. Target disease & number of patients
- Pulpotomy required primary and permanent teeth
- Total amount of teeth involved clinical trial 255 : 151(primary teeth) +104(permanent teeth)
2. Composition of Participants
- Foreign control group ProRootMTA from Densply
- Domestic test group OrthoMTA and RetroMTA from BioMTA
3. Methodology
- Regular clinical and radiographic follow-up examinations for 6 months (permanent teeth) or 12months (primary teeth)
Ⅲ. Result
1. The result of pulpotomy in primary teeth
Out of 151 teeth in the study, 109 teeth were followed-up at 12 months after the treatment. The radiographic success rate of the ProRootMTA? ,the OrthoMTA? and the RetroMTA? was 96, 92.3, 96% respectively and the corresponding clinical success rate was individually 100% 97.4%, 100%. In addition, there were no statistical differences among the three different partial pulpotomy materials in primary teeth.
2. The result of pulpotomy in permanent teeth
Out of 104 teeth in the study, 76 teeth were followed-up at 12 months after the treatment, The clinical success rate of the ProRootMTA? ,the OrthoMTA? and, the RetroMTA? was 96, 92.3, 96% respectively. There were no statistical differences among the three different partial pulpotomy materials in permanent teeth .
Ⅳ. Future Plan
- This research verified the validity of the domestic MTA. Based upon this research, we expect the generalization of the
pulpotomy which is a conservative therapeutic treatment due to the relative lower cost. Moreover, our research will contribute to the public health improvements and the cost savings.
- The domestic MTA will replace the imported MTA and also will be used as evidence backing up the effect of export.
(especially Japan)